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arXiv · 0804.3826

Radiotherapy using a laser proton accelerator

Masao Murakami·Yoshio Hishikawa·Satoshi Miyajima·Yoshiko Okazaki·Kenneth L. Sutherland·Mitsuyuki Abe·Sergei V. Bulanov·Hiroyuki Daido·Timur Zh. Esirkepov·James Koga·Mitsuru Yamagiwa·Toshiki Tajima
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Abstract

Laser acceleration promises innovation in particle beam therapy of cancer where an ultra-compact accelerator system for cancer beam therapy can become affordable to a broad range of patients. This is not feasible without the introduction of a technology that is radically different from the conventional accelerator-based approach. The laser acceleration method provides many enhanced capabilities for the radiation oncologist. It reduces the overall system size and weight by more than one order of magnitude. The characteristics of the particle beams (protons) make them suitable for a class of therapy that might not be possible with the conventional accelerator, such as the ease for changing pulse intensity, the focus spread, the pinpointedness, and the dose delivery in general. A compact, uncluttered system allows a PET device to be located in the vicinity of the patient in concert with the compact gantry. The radiation oncologist may be able to irradiate a localized tumor by scanning with a pencil-like particle beam while ascertaining the actual dosage in the patient with an improved in-beam PET verification of auto-radioactivation induced by the beam therapy. This should yield an unprecedented flexibility in the feedback radiotherapy by the radiation oncologist. Laser accelerated radiotherapy has a unique niche in a current world of high energy accelerator using synchrotron or cyclotron.

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Masao Murakami, Yoshio Hishikawa, Satoshi Miyajima, Yoshiko Okazaki, Kenneth L. Sutherland, Mitsuyuki Abe, Sergei V. Bulanov, Hiroyuki Daido, Timur Zh. Esirkepov, James Koga, Mitsuru Yamagiwa, Toshiki Tajima. 2008-04-24. Radiotherapy using a laser proton accelerator. https://doi.org/10.1063/1.2958203

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