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arXiv · 0809.4602

Dynamics of a bubble formed in double stranded DNA

Shikha Srivastava·Yashwant Singh
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Abstract

We study the fluctuational dynamics of a tagged base-pair in double stranded DNA. We calculate the drift force which acts on the tagged base-pair using a potential model that describes interactions at base pairs level and use it to construct a Fokker-Planck equation.The calculated displacement autocorrelation function is found to be in very good agreement with the experimental result of Altan-Bonnet {\it et. al.} Phys. Rev. Lett. {\bf 90}, 138101 (2003) over the entire time range of measurement. We calculate the most probable displacements which predominately contribute to the autocorrelation function and the half-time history of these displacements.

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Shikha Srivastava, Yashwant Singh. 2008-09-26. Dynamics of a bubble formed in double stranded DNA. https://doi.org/10.1209/0295-5075/85/38001

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