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arXiv · 1004.4394

Ion irradiation and biomolecular radiation damage II. Indirect effect

Wei Wang·Zengliang Yu·Wenhui Su
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Abstract

It has been reported that damage of genome in a living cell by ionizing radiation is about one-third direct and two-thirds indirect. The former which has been introduced in our last paper, concerns direct energy deposition and ionizing reactions in the biomolecules; the latter results from radiation induced reactive species (mainly radicals) in the medium (mainly water) surrounding the biomolecules. In this review, a short description of ion implantation induced radical formation in water is presented. Then we summarize the aqueous radical reaction chemistry of DNA, protein and their components, followed by a brief introduction of biomolecular damage induced by secondary particles (ions and electron). Some downstream biological effects are also discussed.

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Wei Wang, Zengliang Yu, Wenhui Su. 2010-04-26. Ion irradiation and biomolecular radiation damage II. Indirect effect. https://arxiv.org/abs/1004.4394

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