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arXiv · 1309.2087

Baa.pl: A tool to evaluate de novo genome assemblies with RNA transcripts

Joseph F. Ryan
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Abstract

Assessing the correctness of genome assemblies is an important step in any genome project. Several methods exist, but most are computationally intensive and, in some cases, inappropriate. Here I present baa.pl, a fast and easy-to-use program that uses transcript data to evaluate genomic assemblies. Through simulations using human chromosome 22, I show that baa.pl excels at detecting levels of missing sequence and contiguity. The program is freely available at: https://github.com/josephryan/baa.pl

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Joseph F. Ryan. 2014-02-07. Baa.pl: A tool to evaluate de novo genome assemblies with RNA transcripts. https://arxiv.org/abs/1309.2087

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