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arXiv · 1503.02117

Differential Evolution Approach to Detect Recent Admixture

Konstantin Kozlov·Dmitry Chebotarov·Mehedi Hassan·Martin Triska·Petr Triska·Pavel Flegontov·Tatiana Tatarinova
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Abstract

The genetic structure of human populations is extraordinarily complex and of fundamental importance to studies of anthropology, evolution, and medicine. As increasingly many individuals are of mixed origin, there is an unmet need for tools that can infer multiple origins. Misclassification of such individuals can lead to incorrect and costly misinterpretations of genomic data, primarily in disease studies and drug trials. We present an advanced tool to infer ancestry that can identify the biogeographic origins of highly mixed individuals. reAdmix is an online tool available at http://chcb.saban-chla.usc.edu/reAdmix/.

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Konstantin Kozlov, Dmitry Chebotarov, Mehedi Hassan, Martin Triska, Petr Triska, Pavel Flegontov, Tatiana Tatarinova. 2015-03-07. Differential Evolution Approach to Detect Recent Admixture. https://doi.org/10.1186/1471-2164-16-s8-s9

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