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arXiv · 1807.08994

Forced- and Self-Rotation of Magnetic Nanorods Assembly at the Cell Membrane: A Biomagnetic Torsion Pendulum

François Mazuel·Samuel Mathieu·Riccardo Di Corato·Jean-Claude Bacri·Thierry Meylheuc·Teresa Pellegrino·Myriam Reffay·Claire Wilhelm
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Abstract

In order to give insights into how anisotropic nano-objects interact with living cell membranes, and possibly self-assemble, we designed magnetic nanorods with average size around 100 nm x 1$\mu$m by assembling iron oxide nanocubes within a polymeric matrix under a magnetic field. We then explored the nano-bio interface at the cell membrane under the influence of a rotating magnetic field. We observed a complex structuration of the nanorods intertwined with the membranes. Unexpectedly, after a magnetic rotating stimulation, the resulting macrorods were able to rotate freely for multiple rotations, revealing the creation of a bio-magnetic torsion pendulum.

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François Mazuel, Samuel Mathieu, Riccardo Di Corato, Jean-Claude Bacri, Thierry Meylheuc, Teresa Pellegrino, Myriam Reffay, Claire Wilhelm. 2018-07-24. Forced- and Self-Rotation of Magnetic Nanorods Assembly at the Cell Membrane: A Biomagnetic Torsion Pendulum. https://doi.org/10.1002/smll.201701274

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