Search arXiv⌕ Search
Home/Archive/arXiv

arXiv · 1811.06699

On a Cahn-Hilliard-Brinkman model for tumour growth and its singular limits

Matthias Ebenbeck·Harald Garcke
View original source ↗Read source document ↗Export metadata ↓

Abstract

In this work, we study a model consisting of a Cahn-Hilliard-type equation for the concentration of tumour cells coupled to a reaction-diffusion type equation for the nutrient density and a Brinkman-type equation for the velocity. We equip the system with Neumann boundary for the tumour cell variable and the chemical potential, Robin-type boundary conditions for the nutrient and a "no-friction" boundary condition for the velocity, which allows us to consider solution dependent source terms. Well-posedness of the model as well as existence of strong solutions will be established for a broad class of potentials. We will show that in the singular limit of vanishing viscosity we recover a Darcy-type system related to Cahn-Hilliard-Darcy type models for tumour growth which have been studied earlier. An asymptotic limit will show that the results are also valid in the case of Dirichlet boundary conditions for the nutrient.

Explore related subjects

math.AP

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

Matthias Ebenbeck, Harald Garcke. 2018-11-16. On a Cahn-Hilliard-Brinkman model for tumour growth and its singular limits. https://arxiv.org/abs/1811.06699

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related papers

arXiv2026

Multilayered fluid-structure interactions: existence of weak solutions for time-periodic and initial-value problems

We establish the existence of weak solutions for a class of fully coupled multilayered fluid-structure interaction systems in a three-dimensional spatial setting. The model consists of an incompressible viscous fluid interacting with a thin elastic shell, which is in turn coupled to a three-dimensional elastic solid, yielding a nonstandard $3D/2D/3D$ coupling configuration. The system is driven by time-periodic boundary forcing through Bernoulli-type pressure conditions. For sufficiently small forcing in $L^2$, we prove the existence of at least one time-periodic weak solution. A central analytical difficulty stems from the strong nonlinear coupling across interfaces of different dimensionality and the absence of classical compactness mechanisms. This challenge is overcome through a carefully designed energy framework combined with and new $L^{2}$ compactness arguments adapted to the multilayered geometry. A key structural assumption is the viscoelasticity of the three-dimensional solid, which yields additional diffusion estimates and ensures energy stability. In the purely elastic case, we establish the global-in-time existence of weak solutions to the corresponding initial-value problem, provided that no degeneration (self-contact) of the fluid domain occurs. These results extend existing theories for two-dimensional and reduced-dimensional configurations to a genuinely three-dimensional multilayered setting, providing new analytical insight into complex coupled PDE systems arising in fluid-structure interaction.

math.AP↗
arXiv2026

A linear test approach to global controllability of third- and fifth-order nonlinear dispersive equations

We investigate third- and fifth-order nonlinear dispersive equations of KdV type on the torus and establishes approximate controllability by a fixed four-dimensional control; rather than relying solely on the saturation machinery, the analysis exploits the finite-dimensional controllability of the inviscid Burgers equation linearized around a carefully constructed return trajectory, with the trajectory itself obtained from an observable family. This ``linear test" strategy, yields more information about the structure of the control than the standard approach. In particular, the constructed control is shown to depend continuously on the initial and target states, a property that is by no means automatic in nonlinear control problems, and to decompose as a bounded linear operator applied to the data plus a fixed remainder, with the operator part interestingly independent of the order of dispersion.

math.AP↗
arXiv2026

Global in-time rough large data solution to complex-valued semilinear damped evolution equations

We study the semilinear Cauchy problem for complex-valued damped evolution equations \begin{align*} \partial_t^2u+(-Δ)^σu+(-Δ)^δ\partial_tu=u^p,\ \ u(0,x)=u_0(x),\ \partial_tu(0,x)=u_1(x), \end{align*} with $δ\in[0,σ]$, $σ\in\mathbb{R}_+$ and $p\in\mathbb{N}_+\backslash\{1\}$, where the initial data belong to the rough space $E^α_s$ endowed with the norm \begin{align*} \|f\|_{E^α_s}=\big\|\langleξ\rangle^s\,2^{α|ξ|}\widehat{f}(ξ)\big\|_{L^2}\ \ \mbox{with}\ \ α<0, \ s\in\mathbb{R}. \end{align*} Concerning $(u_0,u_1)\in E^α_{s+\barκ}\times E^α_s$ when $s\geqslant\frac{n}{2}-\frac{2κ+\barκ-2δ}{p-1}-\barκ$ with $κ=\min\{2δ,σ\}$ and $\barκ=\max\{2δ,σ\}$ whose Fourier transforms are supported in a suitable subset of first octant, we prove a global in-time existence result without requiring the smallness of rough initial data.

math.AP↗