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arXiv · 1911.11471

Random Forest as a Tumour Genetic Marker Extractor

Raquel Pérez-Arnal·Dario Garcia-Gasulla·David Torrents·Ferran Parés·Ulises Cortés·Jesús Labarta·Eduard Ayguadé
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Abstract

Finding tumour genetic markers is essential to biomedicine due to their relevance for cancer detection and therapy development. In this paper, we explore a recently released dataset of chromosome rearrangements in 2,586 cancer patients, where different sorts of alterations have been detected. Using a Random Forest classifier, we evaluate the relevance of several features (some directly available in the original data, some engineered by us) related to chromosome rearrangements. This evaluation results in a set of potential tumour genetic markers, some of which are validated in the bibliography, while others are potentially novel.

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Raquel Pérez-Arnal, Dario Garcia-Gasulla, David Torrents, Ferran Parés, Ulises Cortés, Jesús Labarta, Eduard Ayguadé. 2019-11-26. Random Forest as a Tumour Genetic Marker Extractor. https://arxiv.org/abs/1911.11471

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