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arXiv · 2004.01011

Microbial populations under selection

Ellen Baake·Anton Wakolbinger
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Abstract

This chapter gives a synopsis of recent approaches to model and analyse the evolution of microbial populations under selection. The first part reviews two population genetic models of Lenski's long-term evolution experiment with Escherichia coli, where models aim at explaining the observed curve of the evolution of the mean fitness. The second part describes a model of a host-pathogen system where the population of pathogenes experiences balancing selection, migration, and mutation, as motivated by observations of the genetic diversity of HCMV (the human cytomegalovirus) across hosts.

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Ellen Baake, Anton Wakolbinger. 2020-04-02. Microbial populations under selection. https://arxiv.org/abs/2004.01011

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