Search arXivSearch

arXiv · 2005.01577

COVID-DA: Deep Domain Adaptation from Typical Pneumonia to COVID-19

Abstract

The outbreak of novel coronavirus disease 2019 (COVID-19) has already infected millions of people and is still rapidly spreading all over the globe. Most COVID-19 patients suffer from lung infection, so one important diagnostic method is to screen chest radiography images, e.g., X-Ray or CT images. However, such examinations are time-consuming and labor-intensive, leading to limited diagnostic efficiency. To solve this issue, AI-based technologies, such as deep learning, have been used recently as effective computer-aided means to improve diagnostic efficiency. However, one practical and critical difficulty is the limited availability of annotated COVID-19 data, due to the prohibitive annotation costs and urgent work of doctors to fight against the pandemic. This makes the learning of deep diagnosis models very challenging. To address this, motivated by that typical pneumonia has similar characteristics with COVID-19 and many pneumonia datasets are publicly available, we propose to conduct domain knowledge adaptation from typical pneumonia to COVID-19. There are two main challenges: 1) the discrepancy of data distributions between domains; 2) the task difference between the diagnosis of typical pneumonia and COVID-19. To address them, we propose a new deep domain adaptation method for COVID-19 diagnosis, namely COVID-DA. Specifically, we alleviate the domain discrepancy via feature adversarial adaptation and handle the task difference issue via a novel classifier separation scheme. In this way, COVID-DA is able to diagnose COVID-19 effectively with only a small number of COVID-19 annotations. Extensive experiments verify the effectiveness of COVID-DA and its great potential for real-world applications.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

Yifan Zhang, Shuaicheng Niu, Zhen Qiu, Ying Wei, Peilin Zhao, Jianhua Yao, Junzhou Huang, Qingyao Wu, Mingkui Tan. 2020-04-30. COVID-DA: Deep Domain Adaptation from Typical Pneumonia to COVID-19. https://arxiv.org/abs/2005.01577

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related papers

IViT: A Novel Interpretable Visual Transformer for Skin Disease Detection

The clinical diagnosis of skin diseases is susceptible to interference from inter-class similarity of skin lesions, and over-reliance on clinicians'experience easily leads to subjective bias. Although existing deep learning aided diagnosis methods achieve competitive accuracy, they suffer from the black-box opacity of Vision Transformer (ViT) and poor adaptability to medical few-shot scenarios. Moreover, mainstream explainable algorithms generally face the bottleneck of significant accuracy degradation when improving interpretability. This paper proposes an interpretable ViT (IViT) constrained by Quadratic Programming (QP). The introduced pre-trained transfer learning adapts to few-shot feature extraction. A discrete QP feature selection framework is constructed to screen generic and discriminative features consistent with clinical diagnostic logic. A multi-objective loss function is designed to reduce feature redundancy and optimize activation distribution while preserving classification performance. Experimental results on six standard skin disease datasets show that IViT achieves an accuracy of 93.80%, only 0.21% lower than the baseline, with feature redundancy reduced by 29.5%. Its core activation regions are consistent with clinically concerned lesion areas. The proposed model balances accuracy and interpretability, providing a reliable solution for the clinical deployment of few-shot intelligent skin disease diagnosis.

eess.IV

Automated Distinction of Intimal and Medial Intracranial Arterial Calcification from CT Head

Intracranial arterial calcifications (IACs) are a common finding on clinical non-contrast enhanced head CT scans and are associated with neurovascular disease. Calcifications can occur in the intimal or medial layer of the arterial wall, subtypes that differ in aetiology and may have distinct clinical relevance. These subtypes can be visually distinguished by radiologists based on the shape of the calcifications. We investigate three automated approaches for subtype classification of IAC from head CT-derived segmentation masks: (1) an automated adaptation of the established radiological visual score, (2) a sphericity-based method, and (3) a method based on shape embeddings extracted by a medical shape foundation model. All approaches use the same lightweight classification pipeline on top of the features they compute and are evaluated using 5-fold cross-validation. The three methods achieved comparable performance, with the embedding-based approach yielding the best overall results with a weighted F1 (mean $\pm$ SD) of up to 71.5 $\pm$ 3.7 for a single artery and 59.8 $\pm$ 1.7 for the joint artery classification. Performance was largely preserved when using automated instead of manual IAC segmentation masks, and we found the difference in weighted F1 not significant. Our results show that fully automated IAC subtype quantification from head CT is feasible and remains robust to the use of manual and automated IAC segmentation masks. Code at https://github.com/bjin96/iac-subtyping.

eess.IV

Recasting the Destroy Step of Large Neighborhood Search as Dense Segmentation

Large neighborhood search improves an incumbent by releasing selected variables and repairing the resulting subproblem under a time limit. FOVEA casts variable selection as dense semantic segmentation on a fixed $128\times128$ canvas. A small U-Net reads twelve semantic channels and predicts cell scores, which are decoded into a variable set subject to a fixed variable budget. Family-specific layouts connect the search state to the canvas, while one set of network weights serves four problem families. The FP32 network input occupies $786$\,kB across instance sizes. Our analysis bounds constraint coupling for spatially coherent regions, gives a rank certificate for rounds with zero possible improvement, and bounds the coupling advantage attainable on an expander family. On the tested families and hardware, FOVEA trails the strongest graph encoder at $10^{4}$ variables and overtakes it near $1.5\times10^{4}$; the cost model provides an approximate crossover estimate. At larger sizes, where the graph-encoder baselines exceed device memory, FOVEA reduces the primal integral by $12$ to $16\%$ relative to the best runnable baselines. On the expander family, FOVEA performs comparably to random selection, with a coupling advantage close to one.

eess.IV