Dampening effect of logistic source in a two-dimensional haptotaxis system with nonlinear zero-order interaction

Abstract

This paper deals with the oncolytic virotherapy model \begin{equation}\begin{split} \begin{cases} &u_t = Δu - \nabla \cdot (u\nabla v)-uz +μu(1-u),& \\[2ex] &v_t = - (u+w)v,& \\[2ex] &w_t = D_w Δw - w + uz,& \\[2ex] &z_t = D_z Δz - z - uz + βw,& \end{cases} \end{split}\end{equation} in a bounded domain $Ω$ $\subset$ $\Bbb{R}^2$ with smooth boundary, where $μ$, $D_w$, $D_z$ and $β$ are prescribed positive parameters. For any given suitably regular initial data, the global existence of classical solution to the corresponding homogeneous Neumann initial-boundary problem for a more general model allowing $μ=0$ was previously verified in $[$Y. Tao $\&$ M. Winkler, J. Differential Equations $\mathbf{268}$ (2020), 4973-4997$]$. This work further shows that whenever $μ>0$, the above-mentioned global classical solution to the above equation is uniformly bounded; and moreover, if $β<1$, then the solution $(u, v, w, z)$ stabilizes to the constant equilibrium $(1, 0, 0, 0)$ in the topology $L^p(Ω)\times (L^\infty(Ω))^3$ with any $p>1$ in a large time limit.