Dengue Seasonality and Non-Monotonic Response to Moisture: A Model-Data Analysis of Sri Lanka Incidence from 2011 to 2016

Milad Hooshyar; Caroline E. Wagner; Rachel E. Baker; Wenchang Yang; Gabriel A. Vecchi; C. Jessica E. Metcalf; Bryan T. Grenfell; Amilcare Porporato

arXiv · 2009.02847

Dengue Seasonality and Non-Monotonic Response to Moisture: A Model-Data Analysis of Sri Lanka Incidence from 2011 to 2016

Milad Hooshyar·Caroline E. Wagner·Rachel E. Baker·Wenchang Yang·Gabriel A. Vecchi·C. Jessica E. Metcalf·Bryan T. Grenfell·Amilcare Porporato

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Abstract

Dengue fever impacts populations across the tropics. Dengue is caused by a mosquito transmitted flavivirus and its burden is projected to increase under future climate and development scenarios. The transmission process of dengue virus is strongly moderated by hydro-climatic conditions that impact the vector's life cycle and behavior. Here, we study the impact of rainfall seasonality and moisture availability on the monthly distribution of reported dengue cases in Sri Lanka. Through cluster analysis, we find an association between seasonal peaks of rainfall and dengue incidence with a two-month lag. We show that a hydrologically driven epidemiological model (HYSIR), which takes into account hydrologic memory in addition to the nonlinear dynamics of the transmission process, captures the two-month lag between rainfall and dengue cases seasonal peaks. Our analysis reveals a non-monotonic dependence of dengue cases on moisture, whereby an increase of cases with increasing moisture is followed by a reduction for very high levels of water availability. Improvement in prediction of the seasonal peaks in dengue incidence results from a seasonally varying dependence of transmission rate on water availability.

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Milad Hooshyar, Caroline E. Wagner, Rachel E. Baker, Wenchang Yang, Gabriel A. Vecchi, C. Jessica E. Metcalf, Bryan T. Grenfell, Amilcare Porporato. 2020-09-07. Dengue Seasonality and Non-Monotonic Response to Moisture: A Model-Data Analysis of Sri Lanka Incidence from 2011 to 2016. https://arxiv.org/abs/2009.02847

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