Search arXivSearch

arXiv · 2105.05874

The Federated Tumor Segmentation (FeTS) Challenge

Abstract

This manuscript describes the first challenge on Federated Learning, namely the Federated Tumor Segmentation (FeTS) challenge 2021. International challenges have become the standard for validation of biomedical image analysis methods. However, the actual performance of participating (even the winning) algorithms on "real-world" clinical data often remains unclear, as the data included in challenges are usually acquired in very controlled settings at few institutions. The seemingly obvious solution of just collecting increasingly more data from more institutions in such challenges does not scale well due to privacy and ownership hurdles. Towards alleviating these concerns, we are proposing the FeTS challenge 2021 to cater towards both the development and the evaluation of models for the segmentation of intrinsically heterogeneous (in appearance, shape, and histology) brain tumors, namely gliomas. Specifically, the FeTS 2021 challenge uses clinically acquired, multi-institutional magnetic resonance imaging (MRI) scans from the BraTS 2020 challenge, as well as from various remote independent institutions included in the collaborative network of a real-world federation (https://www.fets.ai/). The goals of the FeTS challenge are directly represented by the two included tasks: 1) the identification of the optimal weight aggregation approach towards the training of a consensus model that has gained knowledge via federated learning from multiple geographically distinct institutions, while their data are always retained within each institution, and 2) the federated evaluation of the generalizability of brain tumor segmentation models "in the wild", i.e. on data from institutional distributions that were not part of the training datasets.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

Sarthak Pati, Ujjwal Baid, Maximilian Zenk, Brandon Edwards, Micah Sheller, G. Anthony Reina, Patrick Foley, Alexey Gruzdev, Jason Martin, Shadi Albarqouni, Yong Chen, Russell Taki Shinohara, Annika Reinke, David Zimmerer, John B. Freymann, Justin S. Kirby, Christos Davatzikos, Rivka R. Colen, Aikaterini Kotrotsou, Daniel Marcus, Mikhail Milchenko, Arash Nazeri, Hassan Fathallah-Shaykh, Roland Wiest, Andras Jakab, Marc-Andre Weber, Abhishek Mahajan, Lena Maier-Hein, Jens Kleesiek, Bjoern Menze, Klaus Maier-Hein, Spyridon Bakas. 2021-05-14. The Federated Tumor Segmentation (FeTS) Challenge. https://doi.org/10.1038/s41467-025-60466-1

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related papers

LaminoDiff: Generative Computed Laminography via Near-Isotropic Spectral Supervision and Anisotropic Geometry

Computed Laminography (CL) is widely used for nondestructive inspection of extended planar objects, but its restricted angular coverage produces an anisotropic point spread function, missing-cone spectral incompleteness, and severe aliasing with interlayer leakage. This paper presents LaminoDiff, a physics-constrained diffusion framework for CL reconstruction. During training, a CT-derived near-isotropic supervision target is reconstructed from full-angle Computed Tomography (CT) projections physically degraded to match CL detector noise and focal-spot blur while retaining full angular coverage; it is withheld from inference. At inference, the reverse process uses only the CL observation. An Anisotropic Representation (AR) constructs depth-aware channels from three adjacent slices: a neighbor average, a center-neighbor residual, and the retained current slice, followed by directional in-plane feature extraction. Experiments on simulated and real multilayer printed circuit board data, including ball grid array and high-frequency stub samples, show that LaminoDiff improves artifact suppression, edge preservation, and depth stratification over analytic Feldkamp--Davis--Kress and representative learning-based baselines.

eess.IV

IViT: A Novel Interpretable Visual Transformer for Skin Disease Detection

The clinical diagnosis of skin diseases is susceptible to interference from inter-class similarity of skin lesions, and over-reliance on clinicians'experience easily leads to subjective bias. Although existing deep learning aided diagnosis methods achieve competitive accuracy, they suffer from the black-box opacity of Vision Transformer (ViT) and poor adaptability to medical few-shot scenarios. Moreover, mainstream explainable algorithms generally face the bottleneck of significant accuracy degradation when improving interpretability. This paper proposes an interpretable ViT (IViT) constrained by Quadratic Programming (QP). The introduced pre-trained transfer learning adapts to few-shot feature extraction. A discrete QP feature selection framework is constructed to screen generic and discriminative features consistent with clinical diagnostic logic. A multi-objective loss function is designed to reduce feature redundancy and optimize activation distribution while preserving classification performance. Experimental results on six standard skin disease datasets show that IViT achieves an accuracy of 93.80%, only 0.21% lower than the baseline, with feature redundancy reduced by 29.5%. Its core activation regions are consistent with clinically concerned lesion areas. The proposed model balances accuracy and interpretability, providing a reliable solution for the clinical deployment of few-shot intelligent skin disease diagnosis.

eess.IV

Automated Distinction of Intimal and Medial Intracranial Arterial Calcification from CT Head

Intracranial arterial calcifications (IACs) are a common finding on clinical non-contrast enhanced head CT scans and are associated with neurovascular disease. Calcifications can occur in the intimal or medial layer of the arterial wall, subtypes that differ in aetiology and may have distinct clinical relevance. These subtypes can be visually distinguished by radiologists based on the shape of the calcifications. We investigate three automated approaches for subtype classification of IAC from head CT-derived segmentation masks: (1) an automated adaptation of the established radiological visual score, (2) a sphericity-based method, and (3) a method based on shape embeddings extracted by a medical shape foundation model. All approaches use the same lightweight classification pipeline on top of the features they compute and are evaluated using 5-fold cross-validation. The three methods achieved comparable performance, with the embedding-based approach yielding the best overall results with a weighted F1 (mean $\pm$ SD) of up to 71.5 $\pm$ 3.7 for a single artery and 59.8 $\pm$ 1.7 for the joint artery classification. Performance was largely preserved when using automated instead of manual IAC segmentation masks, and we found the difference in weighted F1 not significant. Our results show that fully automated IAC subtype quantification from head CT is feasible and remains robust to the use of manual and automated IAC segmentation masks. Code at https://github.com/bjin96/iac-subtyping.

eess.IV