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arXiv · 2112.12874

ATP Synthase: A Moonlighting Enzyme with Unprecedented Functions

Jean-Nicolas Vigneau·Peyman Fahimi·Maximilian Ebert·Youji Cheng·Connor Tannahill·Paul Muir·Thanh-Tung Nguyen-Dang·Cherif F. Matta
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Abstract

ATP synthase's intrinsic molecular electrostatic potential (MESP) adds constructively to, and hence reinforces, the chemiosmotic voltage. This ATP synthase voltage represents a new free energy term that appears to have been overlooked. This term is at least roughly equal in order of magnitude and opposite in sign to the energy needed to be dissipated as a Maxwell's demon (Landauer principle).

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Jean-Nicolas Vigneau, Peyman Fahimi, Maximilian Ebert, Youji Cheng, Connor Tannahill, Paul Muir, Thanh-Tung Nguyen-Dang, Cherif F. Matta. 2021-12-23. ATP Synthase: A Moonlighting Enzyme with Unprecedented Functions. https://doi.org/10.1039/d1cc06793a

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