Search arXivSearch

arXiv · 2204.10882

Cluster Detection Capabilities of the Average Nearest Neighbor Ratio and Ripley's K Function on Areal Data: an Empirical Assessment

Abstract

Spatial clustering detection methods are widely used in many fields including epidemiology, ecology, biology, physics, and sociology. In these fields, areal data is often of interest; such data may result from spatial aggregation (e.g. the number disease cases in a county) or may be inherent attributes of the areal unit as a whole (e.g. the habitat suitability of conserved land parcel). This study aims to assess the performance of two spatial clustering detection methods on areal data: the average nearest neighbor (ANN) ratio and Ripley's K function. These methods are designed for point process data, but their ease of implementation in GIS software (e.g., in ESRI ArcGIS) and the lack of analogous methods for areal data have contributed to their use for areal data. Despite the popularity of applying these methods to areal data, little research has explored their properties in the areal data context. In this paper we conduct a simulation study to evaluate the performance of each method for areal data under various areal structures and types of spatial dependence. These studies find that traditional approach to hypothesis testing using the ANN ratio or Ripley's K function results in inflated empirical type I rates when applied to areal data. We demonstrate that this issue can be remedied for both approaches by using Monte Carlo methods which acknowledge the areal nature of the data to estimate the distribution of the test statistic under the null hypothesis. While such an approach is not currently implemented in ArcGIS, it can be easily done in R using code provided by the authors.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

Nadeesha Vidanapathirana, Yuan Wang, Alexander C. McLain, Stella Self. 2022-07-13. Cluster Detection Capabilities of the Average Nearest Neighbor Ratio and Ripley's K Function on Areal Data: an Empirical Assessment. https://arxiv.org/abs/2204.10882

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related papers

Geospatial Foundation Models Capture Health-Relevant Dimensions of Place Beyond Conventional Social Risk Indices

Area-based social risk indices summarize residents' socioeconomic conditions but incompletely capture physical features of place that may affect health. We evaluated whether numerical representations of physical place produced by four geospatial foundation model families from 2022 satellite data explained residual variance in tract-level associations between the Area Deprivation Index, Social Deprivation Index, and Social Vulnerability Index with health outcomes. We used LightGBM to predict variables from the American Community Survey and 40 chronic disease and health-behavior outcomes from CDC PLACES across 82,646 census tracts in the contiguous United States, evaluating performance across 10 held-out states. Among survey variables, models were moderately predictive of some variables including housing type (R-squared up to 0.54) but weak for disability, unemployment, and income disparity. For health outcomes, models explained up to 54% of variance left unexplained by social risk indices, with the largest gains for annual checkups, arthritis, and high blood pressure. Mean total variance explained by geospatial foundation models across the 40 health-related outcomes increased from 0.31 in the smallest tract-size decile to 0.39 in the largest. Geospatial foundation models capture health-relevant features of place not represented by conventional social risk indices and may usefully augment them in epidemiological analyses.

stat.AP

Transporting summary measures of relative effects from randomised trials to the treated patient population: an application to breast cancer endocrine therapy

Randomised trials often report relative treatment effects, such as risk ratios and hazard ratios, for trial populations. Clinical decision-making, however, often benefits from estimates of absolute treatment effects in the population eligible for treatment. Trial participants may not represent this target population well, and restrictions on access to individual participant trial data can further complicate absolute effect estimation. Routine care data are often representative of the target population but may be subject to uncontrolled confounding. We consider estimation of the average treatment effect on the treated (ATT), an absolute measure, by combining a representative sample of treated routine care patients with summary measures (i.e., estimated risk or hazard ratios) from either a randomised trial or a meta-analysis of trials. Under marginal or conditional transportability assumptions, the ATT is shown to be identifiable. The implications of collapsibility of the effect measure on transportability are discussed, and plug-in estimators of the ATT are presented. Simulation studies are used to assess finite sample performance of the estimators in a range of settings. The proposed methods are applied to estimate the ATT of endocrine therapy on 15-year breast cancer mortality using results from a meta-analysis of randomised trials and England's National Disease Registration Service.

stat.AP

Overcoming Model Misspecification in Bayesian Inference of Molecular Signalling Networks

Bayesian inference of molecular signalling networks usually relies on tractability of the marginal likelihood, enabling the set of possible networks to be efficiently explored. As such, linear models with independent errors and conjugate priors are routinely used. However, the dynamics of molecular signalling are nonlinear, and relevant confounders are often unobserved; failure to account for these complexities will almost certainly lead to over-confident inferences in the standard Bayesian framework. To confront this reality, we develop a post-Bayesian approach to inference of molecular signalling networks, guided by the principle that uncertainty should not vanish when the statistical model is misspecified, even in the infinite-data limit. Technically, we extend the predictively-oriented (PrO) posterior of McLatchie et al. (2025) to the setting of latent variable models, empirically investigating the properties of PrO posteriors in the challenging network inference context.

stat.AP