IL-MCAM: An interactive learning and multi-channel attention mechanism-based weakly supervised colorectal histopathology image classification approach

Haoyuan Chen; Chen Li; Xiaoyan Li; Md Mamunur Rahaman; Weiming Hu; Yixin Li; Wanli Liu; Changhao Sun; Hongzan Sun; Xinyu Huang; Marcin Grzegorzek

doi:10.1016/j.compbiomed.2022.105265

arXiv · 2206.03368

IL-MCAM: An interactive learning and multi-channel attention mechanism-based weakly supervised colorectal histopathology image classification approach

Haoyuan Chen·Chen Li·Xiaoyan Li·Md Mamunur Rahaman·Weiming Hu·Yixin Li·Wanli Liu·Changhao Sun·Hongzan Sun·Xinyu Huang·Marcin Grzegorzek

View original source ↗Read source document ↗Export metadata ↓

Abstract

In recent years, colorectal cancer has become one of the most significant diseases that endanger human health. Deep learning methods are increasingly important for the classification of colorectal histopathology images. However, existing approaches focus more on end-to-end automatic classification using computers rather than human-computer interaction. In this paper, we propose an IL-MCAM framework. It is based on attention mechanisms and interactive learning. The proposed IL-MCAM framework includes two stages: automatic learning (AL) and interactivity learning (IL). In the AL stage, a multi-channel attention mechanism model containing three different attention mechanism channels and convolutional neural networks is used to extract multi-channel features for classification. In the IL stage, the proposed IL-MCAM framework continuously adds misclassified images to the training set in an interactive approach, which improves the classification ability of the MCAM model. We carried out a comparison experiment on our dataset and an extended experiment on the HE-NCT-CRC-100K dataset to verify the performance of the proposed IL-MCAM framework, achieving classification accuracies of 98.98% and 99.77%, respectively. In addition, we conducted an ablation experiment and an interchangeability experiment to verify the ability and interchangeability of the three channels. The experimental results show that the proposed IL-MCAM framework has excellent performance in the colorectal histopathological image classification tasks.

Explore related subjects

cs.CV

Keep this discovery

Explore connections, maps & timelines

BibTeX RIS

Haoyuan Chen, Chen Li, Xiaoyan Li, Md Mamunur Rahaman, Weiming Hu, Yixin Li, Wanli Liu, Changhao Sun, Hongzan Sun, Xinyu Huang, Marcin Grzegorzek. 2022-06-07. IL-MCAM: An interactive learning and multi-channel attention mechanism-based weakly supervised colorectal histopathology image classification approach. https://doi.org/10.1016/j.compbiomed.2022.105265

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related papers

arXiv2026

SAMReg: SAM-enabled Image Registration with ROI-based Correspondence

This paper describes a new spatial correspondence representation based on paired regions-of-interest (ROIs), for medical image registration. The distinct properties of the proposed ROI-based correspondence are discussed, in the context of potential benefits in clinical applications following image registration, compared with alternative correspondence-representing approaches, such as those based on sampled displacements and spatial transformation functions. These benefits include a clear connection between learning-based image registration and segmentation, which in turn motivates two cases of image registration approaches using (pre-)trained segmentation networks. Based on the segment anything model (SAM), a vision foundation model for segmentation, we develop a new registration algorithm SAMReg, which does not require any training (or training data), gradient-based fine-tuning or prompt engineering. The proposed SAMReg models are evaluated across five real-world applications, including intra-subject registration tasks with cardiac MR and lung CT, challenging inter-subject registration scenarios with prostate MR and retinal imaging, and an additional evaluation with a non-clinical example with aerial image registration. The proposed methods outperform both intensity-based iterative algorithms and DDF-predicting learning-based networks across tested metrics including Dice and target registration errors on anatomical structures, and further demonstrates competitive performance compared to weakly-supervised registration approaches that rely on fully-segmented training data. Open source code and examples are available at: https://github.com/sqhuang0103/SAMReg.git.

cs.CV↗

arXiv2026

Q-SiT: Teaching LMMs for Image Quality Scoring and Interpreting

Image quality scoring and interpreting are two fundamental components of Image Quality Assessment (IQA). The former quantifies image quality, while the latter enables descriptive question answering about image quality. Traditionally, these two tasks have been addressed independently. However, image-quality-specific psychophysical studies suggest that these two tasks are conceptually interconnected: interpreting explicitly represents perceived quality attributes whereas scoring summarizes such evidence into an overall quality judgment. Thus, unifying these capabilities within a single model is both intuitive and logically coherent. In this paper, we propose Q-SiT (Quality Scoring and Interpreting joint Teaching), a unified framework that enables large multimodal models (LMMs) to learn both image quality scoring and interpreting simultaneously. We achieve this by transforming conventional IQA datasets into learnable question-answering datasets and incorporating human-annotated quality interpreting data for training. Furthermore, we introduce an efficient scoring \& interpreting balance strategy, which first determines the optimal data mix ratio on lightweight LMMs and then maps this ratio to primary LMMs for fine-tuning adjustment. This strategy not only mitigates task interference and enhances cross-task knowledge transfer but also significantly reduces computational costs compared to direct optimization on full-scale LMMs. With this joint learning framework and corresponding training strategy, we develop Q-SiT, the first model capable of simultaneously performing image quality scoring and interpreting tasks, along with its lightweight variant, Q-SiT-mini. Experimental results demonstrate that Q-SiT achieves strong performance in both tasks with superior generalization IQA abilities, while Q-SiT-mini significantly reduces computational overhead while maintaining competitive performance.

cs.CV↗

arXiv2026

Preserving Guidance in Cost-Volume Retrieval under Extreme LiDAR Sparsity in Iterative Stereo

While accurate LiDAR depth has been shown to improve stereo matching, high-end LiDAR remains costly and difficult to deploy at scale, motivating guidance from sparse LiDAR measurements. In this paper, we revisit how extremely sparse LiDAR can guide iterative stereo by examining its cost-volume retrieval mechanism. Our analysis shows that LiDAR guidance degrades sharply when only a few hundred points are available, and we provide a signal-processing explanation for why iterative stereo fails to fully exploit such sparse input. This insight leads to a simple yet highly effective remedy: pre-filling the initial disparity map so that cost-volume retrieval becomes more reliable under extremely sparse LiDAR. We find that pre-filling is also effective when injecting LiDAR depth into image features via early fusion, but for a fundamentally different reason, necessitating a distinct pre-filling approach. Combining both forms of guidance, our proposed Guided RAFT-Stereo (GRAFT-Stereo) achieves substantial improvements over existing LiDAR-guided stereo methods across multiple datasets.

cs.CV↗