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arXiv · 2306.02183

brainlife.io: A decentralized and open source cloud platform to support neuroscience research

Soichi Hayashi·Bradley A. Caron·Anibal Sólon Heinsfeld·Sophia Vinci-Booher·Brent McPherson·Daniel N. Bullock·Giulia Bertò·Guiomar Niso·Sandra Hanekamp·Daniel Levitas·Kimberly Ray·Anne MacKenzie·Lindsey Kitchell·Josiah K. Leong·Filipi Nascimento-Silva·Serge Koudoro·Hanna Willis·Jasleen K. Jolly·Derek Pisner·Taylor R. Zuidema·Jan W. Kurzawski·Kyriaki Mikellidou·Aurore Bussalb·Christopher Rorden·Conner Victory·Dheeraj Bhatia·Dogu Baran Aydogan·Fang-Cheng F. Yeh·Franco Delogu·Javier Guaje·Jelle Veraart·Steffen Bollman·Ashley Stewart·Jeremy Fischer·Joshua Faskowitz·Maximilien Chaumon·Ricardo Fabrega·David Hunt·Shawn McKee·Shawn T. Brown·Stephanie Heyman·Vittorio Iacovella·Amanda F. Mejia·Daniele Marinazzo·R. Cameron Craddock·Emanuele Olivetti·Jamie L. Hanson·Paolo Avesani·Eleftherios Garyfallidis·Dan Stanzione·James Carson·Robert Henschel·David Y. Hancock·Craig A. Stewart·David Schnyer·Damian O. Eke·Russell A. Poldrack·Nathalie George·Holly Bridge·Ilaria Sani·Winrich A. Freiwald·Aina Puce·Nicholas L. Port·Franco Pestilli
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Abstract

Neuroscience research has expanded dramatically over the past 30 years by advancing standardization and tool development to support rigor and transparency. Consequently, the complexity of the data pipeline has also increased, hindering access to FAIR (Findable, Accessible, Interoperabile, and Reusable) data analysis to portions of the worldwide research community. brainlife.io was developed to reduce these burdens and democratize modern neuroscience research across institutions and career levels. Using community software and hardware infrastructure, the platform provides open-source data standardization, management, visualization, and processing and simplifies the data pipeline. brainlife.io automatically tracks the provenance history of thousands of data objects, supporting simplicity, efficiency, and transparency in neuroscience research. Here brainlife.io's technology and data services are described and evaluated for validity, reliability, reproducibility, replicability, and scientific utility. Using data from 4 modalities and 3,200 participants, we demonstrate that brainlife.io's services produce outputs that adhere to best practices in modern neuroscience research.

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Soichi Hayashi, Bradley A. Caron, Anibal Sólon Heinsfeld, Sophia Vinci-Booher, Brent McPherson, Daniel N. Bullock, Giulia Bertò, Guiomar Niso, Sandra Hanekamp, Daniel Levitas, Kimberly Ray, Anne MacKenzie, Lindsey Kitchell, Josiah K. Leong, Filipi Nascimento-Silva, Serge Koudoro, Hanna Willis, Jasleen K. Jolly, Derek Pisner, Taylor R. Zuidema, Jan W. Kurzawski, Kyriaki Mikellidou, Aurore Bussalb, Christopher Rorden, Conner Victory, Dheeraj Bhatia, Dogu Baran Aydogan, Fang-Cheng F. Yeh, Franco Delogu, Javier Guaje, Jelle Veraart, Steffen Bollman, Ashley Stewart, Jeremy Fischer, Joshua Faskowitz, Maximilien Chaumon, Ricardo Fabrega, David Hunt, Shawn McKee, Shawn T. Brown, Stephanie Heyman, Vittorio Iacovella, Amanda F. Mejia, Daniele Marinazzo, R. Cameron Craddock, Emanuele Olivetti, Jamie L. Hanson, Paolo Avesani, Eleftherios Garyfallidis, Dan Stanzione, James Carson, Robert Henschel, David Y. Hancock, Craig A. Stewart, David Schnyer, Damian O. Eke, Russell A. Poldrack, Nathalie George, Holly Bridge, Ilaria Sani, Winrich A. Freiwald, Aina Puce, Nicholas L. Port, Franco Pestilli. 2023-08-11. brainlife.io: A decentralized and open source cloud platform to support neuroscience research. https://doi.org/10.1038/s41592-024-02237-2

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