Search arXiv⌕ Search

arXiv · 2307.10048

SIR Epidemics in Interconnected Networks: threshold curve and phase transition

Abstract

To simplify mathematical models of disease spread, we often assume equal contact rates among hosts, but real-world scenarios differ. Network-based frameworks help capture these complexities and structural variations in actual systems. We explore two scenarios involving Susceptible-Infected-Recovered (SIR) dynamics in interconnected networks. First, we study how the epidemic threshold of a contact network changes when coupled with another network, holding infection strength constant. Our model treats both contact networks and interconnections generically. We depict the epidemic threshold curve for interconnected networks, accounting for initial infection in either or both networks. If normalized infection strengths surpass this threshold curve, the disease spreads; below it, it does not, regardless of interconnection level. In the second scenario, we investigate disease spillover, where a novel host population network is affected by a reservoir network. A clear phase transition occurs when the number of links or inter-network infection rate exceeds a threshold while other parameters remain fixed. Spillover exhibits two regimes: major and minor, based on interpopulation links and inter-network infection strength. High spillover probability occurs in the major region and low in the minor. The threshold link count varies with network topology for similar infected numbers in the reservoir network. In sum, our work enhances understanding of SIR dynamics in interconnected networks, offering insights into epidemic behavior in complex systems.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

Saswata Das, Mohammad Hossein Samaei, Caterina Scoglio. 2024-07-02. SIR Epidemics in Interconnected Networks: threshold curve and phase transition. https://arxiv.org/abs/2307.10048

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related papers

Measures of maximal entropy for $C^\infty$ three-dimensional flows

We prove that every $C^\infty$ non-singular flow with positive entropy on a compact three-dimensional manifold without boundary admits finitely many ergodic measures of maximal entropy. This result extends the notable work of Buzzi-Crovisier-Sarig (\emph{Ann. of Math.}, 2022) on surface diffeomorphisms. Our approach differs by addressing the continuity of Lyapunov exponents and the uniform largeness of Pesin sets for measures of maximal entropy. Furthermore, it provides an alternative proof for the case of surface diffeomorphisms.

math.DS↗

Multistationarity in semi-open Phosphorylation-Dephosphorylation Cycles

Multistationarity underlies biochemical switching and cellular decision-making. We study how multistationarity in the sequential $n$-site phosphorylation-dephosphorylation cycle is affected when only some species are open, meaning allowed to exchange with the environment (so-called semi-open networks). Working under mass action kinetics, we obtain two complementary structural results for $n\geq$2. First, opening any nonempty subset of the substrate species preserves the network's capacity for nondegenerate multistationarity. Second, opening the enzyme species (both kinase and phosphatase), possibly together with any subset of substrates, always destroys multistationarity. The latter result is proved by a general reduction framework combining the detection of absolute concentration robustness (ACR) with projection onto the remaining species; when the projection produces a monostationary network, the full semi-open system is monostationary. We also illustrate the general method on multi-layer cascade variants and discuss biological implications.

math.DS↗

Propagation of regularity along unstable manifolds

Let $φ_t : M \to M$ be a flow on a smooth closed connected manifold $M$ that preserves and expands a foliation $F$. We establish a theorem of propagation of regularity along the leaves of $F$ for sections of vector bundles satisfying a transport equation involving the generator of a cocycle over $φ_t$. As a consequence, we prove a regularity result for Pollicott-Ruelle resonant states: if such state is smooth in restriction to a piece of an unstable leaf, then it is in fact smooth over the entire manifold. We also announce further applications related to joint integrability of extreme bundles of partially hyperbolic diffeomorphisms. The proofs rely on a leafwise semiclassical pseudodifferential calculus adapted to a foliated space, which may be of independent interest.

math.DS↗