Search arXiv⌕ Search
Home/Archive/arXiv

arXiv · 2312.16710

Health-related Quality of life, Financial Toxicity, Productivity Loss and Catastrophic Health Expenditures After Lung Cancer Diagnosis in Argentina

Lucas Gonzalez·Andrea Alcaraz·Carolina Gabay·Monica Castro·Silvina Vigo·Eduardo Carinci·Federico Augustovski
View original source ↗Read source document ↗Export metadata ↓

Abstract

Objective: About 12,000 people are diagnosed with lung cancer (LC) each year in Argentina, and the diagnosis has a significant personal and family. The objective of this study was to characterize the Health-Related Quality of Life (HRQoL) and the economic impact in patients with LC and in their households. Methods: Observational cross-sectional study, through validated structured questionnaires to patients with a diagnosis of Non-Small Cell Lung Cancer (NSCLC) in two referral public health care centers in Argentina. Questionnaries used: Health-Related Quality of life (EuroQol EQ-5D-3L questionnaire); financial toxicity (COST questionnaire); productivity loss (WPAI-GH, Work Productivity and Activity Impairment Questionnaire: General Health), and out-of-pocket expenses. Results: We included 101 consecutive patients (mean age 67.5 years; 55.4% men; 57.4% with advanced disease -stage III/IV-). The mean EQ-VAS was 68.8 (SD:18.3), with 82.2% describing fair or poor health. The most affected dimensions were anxiety/depression, pain, and activities of daily living. Patients reported an average 59% decrease in their ability to perform regular daily activities as measured by WPAI-GH. 54.5% reported a reduction in income due to the disease, and 19.8% lost their jobs. The annual economic productivity loss was estimated at USD 2,465 per person. 70.3%) of patients reported financial toxicity. The average out-of-pocket expenditure was USD 100.38 per person per month, which represented 18.5% of household income. Catastrophic expenditures were present in 37.1% of households. When performing subgroup analysis by disease severity, all outcomes were worse in the subpopulation with advanced disease. Conclusions Patients with NSCLC treated in public hospitals in Argentina have significant health-related quality of life and economic impact, worsening in patients with advanced disease.

Explore related subjects

econ.GNq-fin.EC

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

Lucas Gonzalez, Andrea Alcaraz, Carolina Gabay, Monica Castro, Silvina Vigo, Eduardo Carinci, Federico Augustovski. 2023-12-27. Health-related Quality of life, Financial Toxicity, Productivity Loss and Catastrophic Health Expenditures After Lung Cancer Diagnosis in Argentina. https://arxiv.org/abs/2312.16710

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related papers

arXiv2026

Local Media and the Shaping of Social Norms: Evidence from the Ebola outbreak

Media's influence on norms and behavior is widely recognized. Less is known about the role played by media being local. I examine this in a high-stakes context, the Ebola outbreak in Guinea. I exploit quasi-random variation in access to radio and the timing of a public-health campaign aired on community radio. I find that 12-17% of Ebola cases could have been prevented if places with access to a neighboring community radio station had instead had their own. Impacts are driven by radio being local rather than by ethno-linguistic belonging. Local media facilitates coordination in behaviors observed and sanctioned locally.

econ.GN↗
arXiv2026

Productivity Shocks and Input Misallocation: A Decomposition

This paper asks how much input misallocation productivity uncertainty generates and at which stage of input decisions it arises. I separate revenue productivity by when each component is revealed and trace each into the gap between an input's marginal revenue product and its price. In six European countries, shocks revealed after an input is committed account for 20 percent of capital gap dispersion and 5 percent of labor gap dispersion. An unanticipated one percent rise in productivity raises the capital gap by 0.92 percent and the labor gap by 0.19 percent, because most of the shock passes into the wage.

econ.GN↗
arXiv2026

When Do Type-Specific Wages Buffer Distributional Incidence in TANK?

When do relative wages buffer the unequal incidence of aggregate shocks? I derive a consumption-gap decomposition and a present-value condition for partial offset in a TANK model. An extension separates wage-setting demand elasticity from substitution between labor segments and allows each segment to contain both financial types. With a zero inherited wage gap and a same-sign discounted wedge, substitution above one gives offsetting earnings reallocation; substitution below one gives amplification. The channel disappears when financial types have identical segment exposure. Numerical experiments assess these mechanisms, shock persistence, policy feedback, and aggregate-IRF matching. In the nested perfect-alignment monetary benchmark, the peak consumption gap is about two-fifths smaller under type-specific wages than under the common-wage closure. These are conditional model comparisons, not empirical effect estimates or welfare rankings.

econ.GN↗