Search arXiv⌕ Search
Home/Archive/arXiv

arXiv · 2411.05456

Comparative Study of Probabilistic Atlas and Deep Learning Approaches for Automatic Brain Tissue Segmentation from MRI Using N4 Bias Field Correction and Anisotropic Diffusion Pre-processing Techniques

Mohammad Imran Hossain·Muhammad Zain Amin·Daniel Tweneboah Anyimadu·Taofik Ahmed Suleiman
View original source ↗Read source document ↗Export metadata ↓

Abstract

Automatic brain tissue segmentation from Magnetic Resonance Imaging (MRI) images is vital for accurate diagnosis and further analysis in medical imaging. Despite advancements in segmentation techniques, a comprehensive comparison between traditional statistical methods and modern deep learning approaches using pre-processing techniques like N4 Bias Field Correction and Anisotropic Diffusion remains underexplored. This study provides a comparative analysis of various segmentation models, including Probabilistic ATLAS, U-Net, nnU-Net, and LinkNet, enhanced with these pre-processing techniques to segment brain tissues (white matter (WM), grey matter (GM) and cerebrospinal fluid (CSF)) on the Internet Brain Segmentation Repository (IBSR18) dataset. Our results demonstrate that the 3D nnU-Net model outperforms others, achieving the highest mean Dice Coefficient score (0.937 +- 0.012), while the 2D nnU-Net model recorded the lowest mean Hausdorff Distance (5.005 +- 0.343 mm) and the lowest mean Absolute Volumetric Difference (3.695 +- 2.931 mm) across five unseen test samples. The findings highlight the superiority of nnU-Net models in brain tissue segmentation, particularly when combined with N4 Bias Field Correction and Anisotropic Diffusion pre-processing techniques. Our implemented code can be accessed via GitHub.

Explore related subjects

eess.IVcs.CVcs.LG

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

Mohammad Imran Hossain, Muhammad Zain Amin, Daniel Tweneboah Anyimadu, Taofik Ahmed Suleiman. 2024-11-08. Comparative Study of Probabilistic Atlas and Deep Learning Approaches for Automatic Brain Tissue Segmentation from MRI Using N4 Bias Field Correction and Anisotropic Diffusion Pre-processing Techniques. https://arxiv.org/abs/2411.05456

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related papers

arXiv2026

KELP: K-space-conditioned Estimation of Learned Sampling Patterns for Scan-Adaptive Multi-Coil MRI

Deep learning techniques have gained considerable attention for accelerating MRI acquisition while maintaining image quality. In this work, we present a convolutional neural network (CNN)-based framework for predicting scan-adaptive undersampling patterns directly from low-frequency multi-coil $k$-space data. Unlike approaches that optimize sampling patterns during training or rely on nearest-neighbor search at inference, our method is trained using precomputed scan-adaptive optimized masks as supervised labels and predicts a scan-specific sampling pattern in a single forward pass. The training procedure alternates between optimizing the sampling network and a reconstruction network, allowing the learned masks to adapt to reconstruction performance. Experiments on the fastMRI multi-coil knee dataset demonstrate competitive reconstruction quality compared with existing population- and scan-adaptive sampling approaches at $4\times$ and $8\times$ acceleration factors. In addition, the proposed method enables efficient scan-specific mask prediction with inference cost independent of the training dictionary size.

eess.IV↗
arXiv2026

LaminoDiff: Generative Computed Laminography via Near-Isotropic Spectral Supervision and Anisotropic Geometry

Computed Laminography (CL) is widely used for nondestructive inspection of extended planar objects, but its restricted angular coverage produces an anisotropic point spread function, missing-cone spectral incompleteness, and severe aliasing with interlayer leakage. This paper presents LaminoDiff, a physics-constrained diffusion framework for CL reconstruction. During training, a CT-derived near-isotropic supervision target is reconstructed from full-angle Computed Tomography (CT) projections physically degraded to match CL detector noise and focal-spot blur while retaining full angular coverage; it is withheld from inference. At inference, the reverse process uses only the CL observation. An Anisotropic Representation (AR) constructs depth-aware channels from three adjacent slices: a neighbor average, a center-neighbor residual, and the retained current slice, followed by directional in-plane feature extraction. Experiments on simulated and real multilayer printed circuit board data, including ball grid array and high-frequency stub samples, show that LaminoDiff improves artifact suppression, edge preservation, and depth stratification over analytic Feldkamp--Davis--Kress and representative learning-based baselines.

eess.IV↗
arXiv2026

IViT: A Novel Interpretable Visual Transformer for Skin Disease Detection

The clinical diagnosis of skin diseases is susceptible to interference from inter-class similarity of skin lesions, and over-reliance on clinicians'experience easily leads to subjective bias. Although existing deep learning aided diagnosis methods achieve competitive accuracy, they suffer from the black-box opacity of Vision Transformer (ViT) and poor adaptability to medical few-shot scenarios. Moreover, mainstream explainable algorithms generally face the bottleneck of significant accuracy degradation when improving interpretability. This paper proposes an interpretable ViT (IViT) constrained by Quadratic Programming (QP). The introduced pre-trained transfer learning adapts to few-shot feature extraction. A discrete QP feature selection framework is constructed to screen generic and discriminative features consistent with clinical diagnostic logic. A multi-objective loss function is designed to reduce feature redundancy and optimize activation distribution while preserving classification performance. Experimental results on six standard skin disease datasets show that IViT achieves an accuracy of 93.80%, only 0.21% lower than the baseline, with feature redundancy reduced by 29.5%. Its core activation regions are consistent with clinically concerned lesion areas. The proposed model balances accuracy and interpretability, providing a reliable solution for the clinical deployment of few-shot intelligent skin disease diagnosis.

eess.IV↗