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arXiv · 2411.18586

Modeling the Effect of Sleeve Gastrectomy on Gastric Digestion in the Stomach: Insights from Multiphase Flow Modeling

Weixuan Li·Sharun Kuhar·Jung-Hee Seo·Rajat Mittal
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Abstract

The geometry and motility of the stomach play a critical role in the digestion of ingested liquid meals. Sleeve gastrectomy, a common type of bariatric surgery used to reduce the size of the stomach, significantly alters the stomach's anatomy and motility, which impacts gastric emptying and digestion. In this study, we use an imaging data-based computational model, StomachSim, to investigate the consequences of sleeve gastrectomy. The pre-operative stomach anatomy was derived from imaging data and the post-sleeve gastrectomy shapes were generated for different resection volumes. We investigate the effect of sleeve sizes and motility patterns on gastric mixing and emptying. Simulations were conducted using an immersed-boundary flow solver, modeling a liquid meal to analyze changes in gastric content mixing and emptying rates. The results reveal that different degrees of volume reduction and impaired gastric motility have complex effects on stomach's mixing and emptying functions, which are important factors in gastric health of the patient. These findings provide insights into the biomechanical effects of sleeve gastrectomy on gastric digestion and emptying functions, highlighting the potential of computational models to inform surgical planning and post-operative management.

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Weixuan Li, Sharun Kuhar, Jung-Hee Seo, Rajat Mittal. 2024-11-30. Modeling the Effect of Sleeve Gastrectomy on Gastric Digestion in the Stomach: Insights from Multiphase Flow Modeling. https://arxiv.org/abs/2411.18586

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