Search arXiv⌕ Search

arXiv · 2507.01802

The Anatomy of Evidence: An Investigation Into Explainable ICD Coding

Abstract

Automatic medical coding has the potential to ease documentation and billing processes. For this task, transparency plays an important role for medical coders and regulatory bodies, which can be achieved using explainability methods. However, the evaluation of these approaches has been mostly limited to short text and binary settings due to a scarcity of annotated data. Recent efforts by Cheng et al. (2023) have introduced the MDACE dataset, which provides a valuable resource containing code evidence in clinical records. In this work, we conduct an in-depth analysis of the MDACE dataset and perform plausibility evaluation of current explainable medical coding systems from an applied perspective. With this, we contribute to a deeper understanding of automatic medical coding and evidence extraction. Our findings reveal that ground truth evidence aligns with code descriptions to a certain degree. An investigation into state-of-the-art approaches shows a high overlap with ground truth evidence. We propose match measures and highlight success and failure cases. Based on our findings, we provide recommendations for developing and evaluating explainable medical coding systems.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

Katharina Beckh, Elisa Studeny, Sujan Sai Gannamaneni, Dario Antweiler, Stefan Rüping. 2025-07-02. The Anatomy of Evidence: An Investigation Into Explainable ICD Coding. https://arxiv.org/abs/2507.01802

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related papers

MultiViewDx: Evidence-Linked Multi-View Clinical Diagnosis

Medical multimodal large language models (MLLMs) can perform well on existing medical visual question answering (MedVQA) benchmarks, but their training data often does not match clinical diagnosis. Most supervision is organized around isolated images or short QA pairs, leaving two structures weakly specified: how evidence leads to a decision, and how views, series, modalities, and patient context from the same case are linked. We introduce MultiViewDx, a partly physician-validated multimodal instruction dataset for evidence-linked multi-view medical imaging diagnosis. MultiViewDx uses the clinical case as the supervision unit. It links imaging studies with patient context, normalizes heterogeneous reports into an evidence-linked workflow (evidence -> findings -> differential discussion -> diagnosis), and uses a unified image-text retriever to constrain instruction synthesis to source-supported evidence. It covers X-ray, CT, MRI, ultrasound, histopathology, and other clinical visual sources. We fine-tune MultiViewDx-8B-AN and evaluate it on both existing MedVQA benchmarks and real-world case-based diagnostic reasoning. Across four MedVQA benchmarks, it achieves the best average accuracy among compared systems (79.0%), outperforming HuatuoGPT-Vision-34B (66.7%) and Claude3-Opus (55.7%). Beyond MedVQA, on JAMA Clinical Challenge cases, it receives the strongest overall rating under a physician-designed rubric for key clinical points, diagnostic inference, and evidence grounding. Controlled ablations and clinician evaluation show that both case-level multi-view organization and evidence-linked reasoning targets contribute to the gain.

cs.CL↗

Enabling Approximate Joint Sampling in Diffusion LMs

In autoregressive language models, each token is sampled by conditioning on all the past tokens; the overall string has thus been sampled from the correct underlying joint distribution represented by the model. In contrast, masked diffusion language models generate text by unmasking tokens out of order and potentially in parallel. Generating an overall string sampled from the correct underlying joint distribution would (again) require exactly one token unmasking in every full-model forward pass. The more tokens unmasked in parallel, the further away the string is from the true joint; this can be seen in the resulting drop in accuracy (but, increase in speed). In this paper we devise a way to {\em approximately} sample multiple tokens from the joint distribution in a single full-model forward pass; we do so by developing a new lightweight single-layer ``sampler" on top of an existing large diffusion LM. One forward pass of the full model can now be followed by multiple forward passes of only this sampler layer, to yield multiple unmasked tokens. Our sampler is trained to mimic exact joint sampling from the (frozen) full model. We show the effectiveness of our approximate joint sampling for both pretrained-only (Dream-7B-Base, Llada-7B-Base) and instruction-tuned (Dream-7B-Instruct, Dream-7B-Coder) models on language modeling and math \& coding tasks. When four tokens are unmasked for each full-model denoising step, our sampling algorithm achieves a MAUVE score of 0.87 (vs marginal baseline of 0.31) with respect to the true joint distribution.

cs.CL↗

RapidUn: Influence-Driven Parameter Reweighting for Efficient Large Language Model Unlearning

Machine unlearning for large language models (LLMs) remains challenging because full retraining is costly, while approximate methods often struggle to remove targeted behaviors without degrading retained utility, especially under limited post-deployment supervision. We consider a practical PEFT setting for targeted behavioral contamination removal with a small forget set, a limited retain buffer, and LoRA-only updates, and propose RapidUn, an influence-guided framework that converts cross-sample influence estimates into fixed sample-specific weights for weighted LoRA unlearning. Across Llama-3-8B on Dolly-15k and Alpaca-57k, with cross-model validation on Mistral-7B + Dolly-15k, RapidUn achieves lower seen-trigger and OOD-trigger-family ASR than Fisher, GA, and LoReUn while maintaining competitive clean utility. On Llama-3-8B + Alpaca-57k, it achieves a 77x wall-clock speedup over the clean-corpus LoRA retraining reference. Complementary TOFU, semantic LLM-judge, and IFEval evaluations further support the effectiveness of influence-guided sample reweighting beyond the controlled trigger benchmark.

cs.CL↗