Search arXiv⌕ Search
Home/Archive/arXiv

arXiv · 2508.19133

Existence and long-time behavior of global strong solutions to a nonlinear model of tumor growth

Jeffrey Kuan·Konstantina Trivisa
View original source ↗Read source document ↗Export metadata ↓

Abstract

In this manuscript, we study a nonlinear model of tumor growth, described by a coupled hyperbolic-elliptic system of partial differential equations. In this model, the compressible flow of tumor cells is modeled by a transport equation for the cell density, which takes into account transport via a background flow (given by a potential solving a Brinkman-type equation), and which has a source term modeling cell growth and death. In this manuscript, we show that for sufficiently large viscosity, the tumor growth system admits nontrivial global strong solutions for positive initial data having a gradient with sufficiently small norm. This illustrates the regularizing effects of the source term representing tumor cell growth and death on the resulting transport dynamics of the equation. Furthermore, we characterize the long-time behavior of global strong solutions to the tumor growth system using a level-set analysis, in which we analyze how level sets evolve as they are transported by the flow, in terms of expansion/contraction and accretion/depletion of cells. While there has been past work on global existence of weak solutions for this tumor growth system, this manuscript opens the study of well-posedness in terms of more regular strong/classical solutions, which exist globally in time.

Explore related subjects

math.AP

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

Jeffrey Kuan, Konstantina Trivisa. 2025-08-26. Existence and long-time behavior of global strong solutions to a nonlinear model of tumor growth. https://arxiv.org/abs/2508.19133

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related papers

arXiv2026

Large friction limit of compressible Navier--Stokes equations with Navier boundary conditions in a half-space

We study the large-friction limit for the three-dimensional barotropic compressible Navier-Stokes equations in a half-space. The velocity satisfies a Navier boundary condition with friction coefficient $α>0$, while the limiting problem satisfies the no-slip boundary condition. We establish estimates for local-in-time smooth solutions that are uniform in $α$ and prove strong convergence of the density and velocity as $α\to\infty$. For weak solutions, we use the Lagrangian flow maps associated with the two velocities to compare the densities and construct suitable transported test functions. This yields weak convergence to the no-slip solution. Our results provide a compressible counterpart of the large-friction limit for incompressible flows.

math.AP↗
arXiv2026

Bochner-Riesz means for critical magnetic Schrödinger operators in ${\mathbb R^2}$

We study $L^p$-boundedness of the Bochner-Riesz means for critical magnetic Schrödinger operators $\LL_{\A}$ in ${\mathbb R^2}$, which involve the {physical} Aharonov-Bohm potential. We show that for $1\leq p\leq +\infty$ and $p\not= 2$, the Bochner-Riesz operator $S_λ^δ(\LL_{\A})$ of order $δ$ is bounded on $L^p(\R^2)$ if and only if $δ>\max\big\{0, 2\big|1/2-1/p\big|-1/2\big\}$. The new ingredient {in} the proof is to obtain the localized $L^4(\R^2)$ estimate of $S_λ^δ(\LL_{\A})$, whose kernel is heavily affected by the physical magnetic diffraction, and more singular than the classical Bochner-Riesz means $S_λ^δ(Δ)$ for the Laplacian $Δ$ in ${\mathbb R}^2$.

math.AP↗
arXiv2026

Solitons, scattering and blow-up for the nonlinear Schrödinger equation with combined power-type nonlinearities on $\mathbb{R}^d\times\mathbb{T}$

We investigate the long time dynamics of the nonlinear Schrödinger equation (NLS) with combined powers on the waveguide manifold $\mathbb{R}^d\times\mathbb{T}$. Different from the previously studied NLS-models with single power on the waveguide manifolds, where the non-scale-invariance is mainly due to the mixed nature of the underlying domain, the non-scale-invariance of the present model is both geometrical and structural. By considering different combinations of the nonlinearities, we establish both qualitative and quantitative properties of the soliton, scattering and blow-up solutions. As one of the main novelties of the paper compared to the previous results for the NLS with single power, we particularly construct two different rescaled families of variational problems, which leads to an NLS with single power in different limiting profiles respectively, to establish the periodic dependence results.

math.AP↗