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arXiv · 2509.14285

A Multi-Agent LLM Defense Pipeline Against Prompt Injection Attacks

Abstract

Prompt injection attacks represent a major vulnerability in Large Language Model (LLM) deployments, where malicious instructions embedded in user inputs can override system prompts and induce unintended behaviors. This paper presents a novel multi-agent defense framework that employs specialized LLM agents in coordinated pipelines to detect and neutralize prompt injection attacks in real-time. We evaluate our approach using two distinct architectures: a sequential chain-of-agents pipeline and a hierarchical coordinator-based system. Our comprehensive evaluation on 55 unique prompt injection attacks, grouped into 8 categories and totaling 400 attack instances across two LLM platforms (ChatGLM and Llama2), demonstrates significant security improvements. Without defense mechanisms, baseline Attack Success Rates (ASR) reached 30% for ChatGLM and 20% for Llama2. Our multi-agent pipeline achieved 100% mitigation, reducing ASR to 0% across all tested scenarios. The framework demonstrates robustness across multiple attack categories including direct overrides, code execution attempts, data exfiltration, and obfuscation techniques, while maintaining system functionality for legitimate queries.

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S M Asif Hossain, Ruksat Khan Shayoni, Mohd Ruhul Ameen, Akif Islam, M. F. Mridha, Jungpil Shin. 2025-12-17. A Multi-Agent LLM Defense Pipeline Against Prompt Injection Attacks. https://arxiv.org/abs/2509.14285

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