Search arXiv⌕ Search
Home/Archive/arXiv

arXiv · 2511.00355

Analysis of a nonlinear free-boundary tumor model with three layers

Junde Wu·Hao Xu·Yuehong Zhuang
View original source ↗Read source document ↗Export metadata ↓

Abstract

In this paper, we study a nonlinear free boundary problem modeling the growth of spherically symmetric tumors. The tumor consists of a central necrotic core, an intermediate annual quiescent-cell layer, and an outer proliferating-cell layer. The evolution of tumor layers and the movement of the tumor boundary are totally governed by external nutrient supply and conservation of mass. The three-layer structure generates three free boundaries with boundary conditions of different types. We develop a nonlinear analysis method to get over the great difficulty arising from free boundaries and the discontinuity of the nutrient-consumption rate function. By carefully studying the mutual relationships between the free boundaries, we reveal the evolutionary mechanism in tumor growth and the mutual transformation of its internal structures. The existence and uniqueness of the radial stationary solution is proved, and its globally asymptotic stability towards different dormant tumor states is established.

Explore related subjects

math.AP

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

Junde Wu, Hao Xu, Yuehong Zhuang. 2025-11-01. Analysis of a nonlinear free-boundary tumor model with three layers. https://arxiv.org/abs/2511.00355

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related papers

arXiv2026

Large friction limit of compressible Navier--Stokes equations with Navier boundary conditions in a half-space

We study the large-friction limit for the three-dimensional barotropic compressible Navier-Stokes equations in a half-space. The velocity satisfies a Navier boundary condition with friction coefficient $α>0$, while the limiting problem satisfies the no-slip boundary condition. We establish estimates for local-in-time smooth solutions that are uniform in $α$ and prove strong convergence of the density and velocity as $α\to\infty$. For weak solutions, we use the Lagrangian flow maps associated with the two velocities to compare the densities and construct suitable transported test functions. This yields weak convergence to the no-slip solution. Our results provide a compressible counterpart of the large-friction limit for incompressible flows.

math.AP↗
arXiv2026

Bochner-Riesz means for critical magnetic Schrödinger operators in ${\mathbb R^2}$

We study $L^p$-boundedness of the Bochner-Riesz means for critical magnetic Schrödinger operators $\LL_{\A}$ in ${\mathbb R^2}$, which involve the {physical} Aharonov-Bohm potential. We show that for $1\leq p\leq +\infty$ and $p\not= 2$, the Bochner-Riesz operator $S_λ^δ(\LL_{\A})$ of order $δ$ is bounded on $L^p(\R^2)$ if and only if $δ>\max\big\{0, 2\big|1/2-1/p\big|-1/2\big\}$. The new ingredient {in} the proof is to obtain the localized $L^4(\R^2)$ estimate of $S_λ^δ(\LL_{\A})$, whose kernel is heavily affected by the physical magnetic diffraction, and more singular than the classical Bochner-Riesz means $S_λ^δ(Δ)$ for the Laplacian $Δ$ in ${\mathbb R}^2$.

math.AP↗
arXiv2026

Solitons, scattering and blow-up for the nonlinear Schrödinger equation with combined power-type nonlinearities on $\mathbb{R}^d\times\mathbb{T}$

We investigate the long time dynamics of the nonlinear Schrödinger equation (NLS) with combined powers on the waveguide manifold $\mathbb{R}^d\times\mathbb{T}$. Different from the previously studied NLS-models with single power on the waveguide manifolds, where the non-scale-invariance is mainly due to the mixed nature of the underlying domain, the non-scale-invariance of the present model is both geometrical and structural. By considering different combinations of the nonlinearities, we establish both qualitative and quantitative properties of the soliton, scattering and blow-up solutions. As one of the main novelties of the paper compared to the previous results for the NLS with single power, we particularly construct two different rescaled families of variational problems, which leads to an NLS with single power in different limiting profiles respectively, to establish the periodic dependence results.

math.AP↗