Search arXiv⌕ Search
Home/Archive/arXiv

arXiv · 2601.14135

Multi-Tongue Frequency Fractal Dynamics in Hodgkin-Huxley Neurons Induced by Temporal Interference Stimulation

Madhurendra Mishra·Zhen Qi·Adarsh Ganesan
View original source ↗Read source document ↗Export metadata ↓

Abstract

We investigate neuronal excitability in the Hodgkin-Huxley model under temporal interference (TI) stimulation in a previously unexplored sub-Hz resonant regime and uncover a striking nonlinear response that we term 'multi-tongue frequency fractals'. Unlike single-frequency driving, which yields a smooth resonant valley, dual-frequency excitation fragments this response into a hierarchy of sharply modulated tongues whose number and structure grow with observation time, revealing clear self-similar architecture. These features emerge from transitions between non-cascaded and cascaded high-harmonic and sub-harmonic generation as detuning varies, and are maximized near the intrinsic ionic timescale at omega ~ 0.2 rad/s. Parameter sweeps show that the fractal count is higher for higher potassium conductances, lower sodium conductances and lower leak conductances. These results demonstrate that TI stimulation can elicit rich, hierarchically organized frequency responses even in classical excitable membranes, revealing fractal organization in Hodgkin-Huxley dynamics.

Explore related subjects

nlin.PS

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

Madhurendra Mishra, Zhen Qi, Adarsh Ganesan. 2026-01-20. Multi-Tongue Frequency Fractal Dynamics in Hodgkin-Huxley Neurons Induced by Temporal Interference Stimulation. https://arxiv.org/abs/2601.14135

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related papers

arXiv2026

Routes to chaos in a mass-conserving two-species reaction-diffusion model

Mass-conserving reaction-diffusion systems with two species correspond to a seemingly simple case where pattern formation occurs under the influence of a conservation law. Here, we first revisit their linear stability behavior and point out that generically two instabilities can occur: a stationary large-scale mass-conserving (Cahn-Hilliard) instability and an instability that combines features of a stationary large-scale non-mass-conserving (Allen-Cahn) instability and a oscillatory large-scale mass-conserving (conserved-Hopf) instability. We term it an Allen-Cahn-Hopf instability. Second, we investigate the nonlinear dynamics for a specific model related to the formation of cell polarization where only a Cahn-Hilliard instability can occur, i.e., all primary bifurcations are stationary. We analyze how secondary and further bifurcations subsequently give rise to various oscillatory states. The emerging rich spectrum of spatiotemporal behavior includes several period-doubling cascades related to different forms of spatial and temporal symmetry breaking. Beside regular states, three types of low-dimensional spatiotemporal chaos occur and involve transitions like fusion and an outer crises. Our results demonstrate the importance of nonlinear interactions in the dynamics of mass-conserving reaction-diffusion systems, and show that even a simple two-species system with primary bifurcations of Cahn-Hilliard type can show complex spatiotemporal behavior.

nlin.PS↗
arXiv2026

Duck hunting with quantum mechanics

We bridge two sides of singular perturbation theory: the classical theory of slow-fast systems and the semi-classical approach to quantum mechanical systems. For a specific but physically important class of dynamical systems, we show that purely classical and exotic objects, so-called canard solutions, are shadows of instantons in the corresponding quantum system. We demonstrate that canard solutions exist in a domain of parameter space whose boundaries are determined by an instanton action. We illustrate our statements analytically for the relevant example, the overdamped Josephson junction, and confirm them numerically. For the Josephson junction, the canard window is the exponentially narrow gap between consecutive Shapiro steps.

nlin.PS↗