arXiv · 2601.19378
Establishing dermatopathology encyclopedia DermpathNet with Artificial Intelligence-Based Workflow
Abstract
Accessing high-quality, open-access dermatopathology image datasets for learning and cross-referencing is a common challenge for clinicians and dermatopathology trainees. To establish a comprehensive open-access dermatopathology dataset for educational, cross-referencing, and machine-learning purposes, we employed a hybrid workflow to curate and categorize images from the PubMed Central (PMC) repository. We used specific keywords to extract relevant images, and classified them using a novel hybrid method that combined deep learning-based image modality classification with figure caption analyses. Validation on 651 manually annotated images demonstrated the robustness of our workflow, with an F-score of 89.6% for the deep learning approach, 61.0% for the keyword-based retrieval method, and 90.4% for the hybrid approach. We retrieved over 7,772 images across 166 diagnoses and released this fully annotated dataset, reviewed by board-certified dermatopathologists. Using our dataset as a challenging task, we found the current image analysis algorithm from OpenAI inadequate for analyzing dermatopathology images. In conclusion, we have developed a large, peer-reviewed, open-access dermatopathology image dataset, DermpathNet, which features a semi-automated curation workflow.
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Ziyang Xu, Mingquan Lin, Yiliang Zhou, Zihan Xu, Seth J. Orlow, Shane A. Meehan, Alexandra Flamm, Ata S. Moshiri, Yifan Peng. 2026-01-27. Establishing dermatopathology encyclopedia DermpathNet with Artificial Intelligence-Based Workflow. https://arxiv.org/abs/2601.19378
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