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arXiv · 2603.26530

Control of genes by self-organizing multicellular interaction networks

Kyle R. Allison
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Abstract

Multicellular self-organization drives development in biological organisms, yet a comprehensive theory is lacking as basic properties of cells can complicate common approaches. Framing such properties by dynamic graphs led to new theoretical propositions for multicellular self-organization in Escherichia coli. Here, corresponding ideas are developed from biologically-general first principles. The resulting perspective could aid both experimental and computational approaches to multicellular biology as well as efforts to control and engineer it.

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Kyle R. Allison. 2026-03-27. Control of genes by self-organizing multicellular interaction networks. https://doi.org/10.1038/s41540-026-00745-9

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