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arXiv · 2604.03224

HyperCT: Low-Rank Hypernet for Unified Chest CT Analysis

Abstract

Non-contrast chest CTs offer a rich opportunity for both conventional pulmonary and opportunistic extra-pulmonary screening. While Multi-Task Learning (MTL) can unify these diverse tasks, standard hard-parameter sharing approaches are often suboptimal for modeling distinct pathologies. We propose HyperCT, a framework that dynamically adapts a Vision Transformer backbone via a Hypernetwork. To ensure computational efficiency, we integrate Low-Rank Adaptation (LoRA), allowing the model to regress task-specific low-rank weight updates rather than full parameters. Validated on a large-scale dataset of radiological and cardiological tasks, \method{} outperforms various strong baselines, offering a unified, parameter-efficient solution for holistic patient assessment. Our code is available at https://github.com/lfb-1/HyperCT.

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Fengbei Liu, Sunwoo Kwak, Hao Phung, Nusrat Binta Nizam, Ilan Richter, Nir Uriel, Hadar Averbuch-Elor, Daborah Estrin, Mert R. Sabuncu. 2026-04-03. HyperCT: Low-Rank Hypernet for Unified Chest CT Analysis. https://arxiv.org/abs/2604.03224

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