Quasi-birth-and-death processes evolving within trees: Applications to comparative phylogenetics

Abstract

We consider a quasi-birth-and-process (QBD) that duplicates itself at some fixed times within a tree that contains information about duplication times and potentially partially observed states. We analyse a continuous trait by discretising it to obtain the QBD level variable. Then, the phase variable is used to model the dynamics of the underlying environment. Here, we extend the framework of Soewongsono et al. to enable a more general analysis. We develop an efficient recursive algorithm for computing the likelihood of an observed tree under this model and construct several numerical examples to illustrate its application potential. Through our synthetic data examples, we show a range of potential behaviours that could be modelled with this approach. Further, we apply the framework to two empirical examples from comparative phylogenetics (the evolution of range area and body size traits across a phylogeny of 49 mammals) to gain different insights into the evolution of these continuous traits. In this setting duplication of the QBD represents speciation and continuous trait evolution is modelled in a discretised state space. In our empirical examples, we explore the impact of different parameter choices on the corresponding likelihood of observing a given phylogenetic tree and the observed levels at its tips.