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arXiv · 2608.09994

SpecF2M: A Spectral-Aware Multi-task Network Estimating Axial Length and Refractive Error from Pediatric Fundus Photographs

Mengxian He·Xinyue Liu·Yunyun Sun·Wei Hao·Minqing Zhang·Lichun Wang·Shunyi Zhang·Wu Yuan
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Abstract

Spherical Equivalent Refraction (SER) and Axial Length (AL) are core indicators for pediatric myopia screening, yet their measurements require dedicated biometry and cycloplegic refraction. Fundus photography offers an accessible imaging modality, as myopia-related posterior-pole changes are visible in 45$^\circ$ fundus images. However, these cues are often low-contrast, spatially diffuse, and multi-scale. Moreover, AL, Sphere (SPH), and Cylinder (CYL) share partially overlapping but non-identical anatomical correlates. We propose SpecF2M, a spectral-aware multi-task network for estimating AL and SER components from pediatric fundus photographs. SpecF2M integrates a deterministic anatomy-guided enhancement module, a hybrid spatial--spectral backbone combining MixCNN and Hybrid Spectral Learning (HSL) blocks, and an expert-routing head for component-level estimation of AL, SPH, and CYL. On a pediatric cohort of 4,359 eligible child visits and 6,966 fundus images, SpecF2M outperforms controlled CNN/ViT baselines for AL and SPH estimation, achieving MAEs of 0.5347 mm and 0.7062 D, respectively. Component-level analysis further reveals asymmetric task coupling, where CYL exhibits weaker association with fundus-derived myopic patterns than AL/SPH. These results support fundus-based, screening-oriented estimation of pediatric myopia indicators, while external validation remains necessary before deployment.

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Mengxian He, Xinyue Liu, Yunyun Sun, Wei Hao, Minqing Zhang, Lichun Wang, Shunyi Zhang, Wu Yuan. 2026-08-07. SpecF2M: A Spectral-Aware Multi-task Network Estimating Axial Length and Refractive Error from Pediatric Fundus Photographs. https://arxiv.org/abs/2608.09994

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