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arXiv · 2608.10361

Neural implants and human safety: single-fault detection for DC-coupled recording front ends

Abstract

DC-coupled analogue front ends (AFEs) for neural implants provide a low-area solution. However, removing the coupling capacitor eliminates the intrinsic barrier that protects cortical tissue: a single-fault event, such as gate-oxide breakdown of a low-noise amplifier (LNA) input transistor, can open a direct DC path from the supply rail into the brain. On the stimulation side this hazard is well understood, and single-fault tolerance is enforced by a series DC-blocking capacitor; on the recording side, DC-coupled front ends discard the equivalent safeguard, yet their protection has gone almost unexamined. This paper presents a single-fault detection mechanism that monitors the LNA for the DC imbalance produced by such a failure and disables the amplifier before the resulting fault current can irreversibly damage tissue. The imbalance is encoded in the duty cycle of a current-starved relaxation oscillator and read out as a time-to-digital measurement. Designed in 65 nm, the mechanism resolves a worst-case fault of 6.4 nA across all corners within 0.81 ms - compliant with the ISO~14708-3 limit for an 8533 um2 electrode - opening a broader discussion of safety in DC-coupled recording.

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BibTeXRIS

Dimitris Antoniadis, Timothy Constandinou. 2026-08-11. Neural implants and human safety: single-fault detection for DC-coupled recording front ends. https://arxiv.org/abs/2608.10361

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