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arXiv · 2608.25965

Less Contouring, More Accuracy: Lesion-Guided ROI Deep Learning for Ovarian Ultrasound Classification

Mehran Ahmad·Ali Abbasian Ardakani·Afshin Mohammadi·Alisa Mohebbi·Gernot Kronreif·Sepideh Hatamikia
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Abstract

Ovarian lesion classification using transvaginal ultrasound remains challenging due to overlapping imaging characteristics and the dependence on expert interpretation. This study investigates whether lesion-guided region-of-interest (ROI) deep learning can achieve competitive diagnostic performance while reducing the annotation burden associated with pixel-level lesion segmentation. Two publicly available ovarian ultrasound datasets were evaluated: the Multi-Modality Ovarian Tumor Ultrasound (MMOTU) dataset for eight-class classification and the Ovarian Ultrasound Dataset (OUD) for binary classification. Four strategies were compared under a unified framework: global image-based deep learning, lesion-guided ROI-based deep learning, lesion contour-based deep learning, and contour-based radiomics with machine learning classifiers. Four deep learning architectures, MaxViT-Tiny, Swin Transformer, EfficientNet-B7, and ResNet18, were evaluated. Radiomics models were developed using support vector machine, k-nearest neighbors, and artificial neural network classifiers, with ANOVA-based feature selection applied for the lower-sample OUD dataset. The lesion-guided ROI strategy achieved the strongest overall performance, with MaxViT-Tiny obtaining 93.10% accuracy and an AUC of 0.99 on MMOTU and 97.56% accuracy and an AUC of 0.99 on OUD. The contour-based approach achieved comparable accuracy but required substantially higher annotation effort. These findings demonstrate that lesion-guided ROI deep learning provides an effective balance between diagnostic performance and annotation efficiency, offering a practical approach for scalable AI-assisted ovarian ultrasound analysis

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Mehran Ahmad, Ali Abbasian Ardakani, Afshin Mohammadi, Alisa Mohebbi, Gernot Kronreif, Sepideh Hatamikia. 2026-08-26. Less Contouring, More Accuracy: Lesion-Guided ROI Deep Learning for Ovarian Ultrasound Classification. https://arxiv.org/abs/2608.25965

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