Toward Workflow-Aware Benchmarking for Healthcare NLP Agents

Abstract

Large language model (LLM) agents are increasingly proposed for healthcare tasks such as clinical documentation, evidence retrieval, patient messaging, and care coordination. Yet many evaluations remain limited to static medical question answering or one-shot generation, under-representing longitudinal state, interruptions, and human handoffs. We introduce an episode-level evaluation protocol for healthcare NLP agents. The protocol separates evidence across model, agent, and simulated-workflow behavior; specifies a five-field episode schema; and defines annotation and scoring for state continuity, evidence traceability, and escalation decisions. It is instantiated as four task templates: documentation update, evidence retrieval, patient messaging, and triage handoff. The protocol does not claim to measure clinical outcomes or deployment value. Instead, it supplies a reproducible intermediate evaluation layer between static benchmarks and prospective workflow studies, with an explicit cost-sensitive treatment of missed versus unnecessary escalation.