Search arXiv⌕ Search
Home/Archive/arXiv

arXiv · 2609.28321

Long-Term Tail Modeling in Survival Analysis via Extended Generalized Pareto Distributions

Eduardo Janotti·Lígia Henriques-Rodrigues·Antonio Carlos Pedroso de Lima
View original source ↗Read source document ↗Export metadata ↓

Abstract

We propose a class of extended generalized Pareto models for right-censored survival data, with particular emphasis on tail inference and long-term extrapolation. Our framework integrates extreme value theory and survival analysis, combining a generalized Pareto distribution with a flexible perturbation distribution on the unit interval. We consider three perturbation specifications: a parametric Beta model, a Bernstein polynomial estimator, and a histogram-based estimator. To facilitate direct comparison, all three models are fitted using a unified iterative procedure adapted to right censoring through Kaplan-Meier-based pseudo-observations. A Monte Carlo study evaluates finite-sample performance across different tail indices, censoring levels, sample sizes, and model complexities. The results reveal a trade-off between flexibility and stability: the Beta specification generally performs best for tail-index estimation, whereas the histogram estimator performs particularly well for scale estimation under low censoring. The Bernstein estimator shows intermediate performance and greater sensitivity to sample size and censoring. Applications to bladder cancer recurrence and heart-failure survival data show that models with very similar in-sample fits can nevertheless produce markedly different tail-index estimates and long-term extrapolations. These findings emphasize the importance of perturbation specification when extended generalized Pareto models are used for survival extrapolation under censoring.

Explore related subjects

stat.MEmath.STstat.APstat.TH

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

Eduardo Janotti, Lígia Henriques-Rodrigues, Antonio Carlos Pedroso de Lima. 2026-09-23. Long-Term Tail Modeling in Survival Analysis via Extended Generalized Pareto Distributions. https://arxiv.org/abs/2609.28321

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related papers

arXiv2026

Bridging Impulse Control of Piecewise Deterministic Markov Processes and Markov Decision Processes: Frameworks, Extensions, and Open Challenges

Control theory plays a pivotal role in understanding and optimizing the behavior of complex dynamical systems across various scientific and engineering disciplines. Two key frameworks that have emerged for modeling and solving control problems in stochastic systems are piecewise deterministic Markov processes (PDMPs) and Markov decision processes (MDPs). Each framework has its unique strengths, and their intersection offers promising opportunities for tackling a broad class of problems, particularly in the context of impulse controls and decision-making in complex systems. The relationship between PDMPs and MDPs is a natural subject of exploration, as embedding impulse control problems for PDMPs into the MDP framework could open new avenues for their analysis and resolution. Specifically, this integration would allow leveraging the computational and theoretical tools developed for MDPs to address the challenges inherent in PDMPs. On the other hand, PDMPs can offer a versatile and simple paradigm to model continuous time problems that are often described as discrete-time MDPs parametrized by complex transition kernels. This transformation has the potential to bridge the gap between the two frameworks, enabling solutions to previously intractable problems and expanding the scope of both fields. This paper presents a comprehensive review of two research domains, illustrated through a recurring medical example. The example is revisited and progressively formalized within the framework of thevarious concepts and objects introduced

stat.ME↗
arXiv2026

Decision Theoretic Subgroup Detection With Bayesian Machine Learning

We consider the problem of identifying promising subpopulations in terms of treatment effectiveness or treatment effect heterogeneity, from a Bayesian decision theoretic perspective. We first show that a straight-forward application of Bayesian decision theory to subgroup detection leads to a counter-intuitive risk-seeking (RS) behavior. Motivated by this observation, we introduce the Bayesian Risk-Aware Inference and Detection of Subgroups (BRAIDS) utility and use it to perform subgroup selection and post selection inference. The BRAIDS utility interpolates between risk-seeking (RS) and risk-averse (RA) identifications of subgroups, with a variant of the virtual twins algorithm as its risk-neutral midpoint. We also argue that effective subgroup estimation and inference requires the use of regularization priors to safeguard inferences from the winner's curse. We provide empirical evidence that posterior credible intervals for subgroup effects can still obtain nominal coverage levels, provided that an appropriate prior distribution is chosen. The proposed framework is illustrated on data from clinical trial assessing the efficacy of canagliflozin as a treatment for type 2 diabetes.

stat.ME↗
arXiv2026

Modeling cyclostationarity in time series using ASCA

Modern data analysis across diverse disciplines increasingly relies on time series. Many of these datasets exhibit cyclostationarity, where patterns approximately repeat in a regular manner, often across multiple time scales, such as daily, weekly or yearly cycles. In this context, statistical inference is essential to distinguish genuine underlying effects from random variability. While tools like Analysis of Variance (ANOVA) provide such inference, they often lack interpretability and struggle with the complexities of multivariate data. To address these limitations, we propose a unified pipeline for the exploratory analysis of cyclostationary times series using ANOVA Simultaneous Component Analysis (ASCA). ASCA is an extension of ANOVA that is able to work in both univariate and multivariate cases. Combining inference with the visualization capabilities of Principal Component Analysis (PCA), ASCA provides powerful options for interpretability. ASCA's capabilities have been well-established in the analysis of experimental data, but they remain largely unexplored for observational data like time series. Our workflow introduces an algorithmic approach to modeling time-dependent data using ASCA, enabling control over multiple cyclostationary time scales while also accounting for the specific challenges of this type of data, such as autocorrelation. Furthermore, we observed that ASCA provides a better separation of variability across factors than ANOVA in unbalanced designs due to its multivariate nature. We demonstrate the efficacy of this methodology through two real-world case studies: water temperature trends in mountain lakes in Sierra Nevada, Spain, and airborne pollen trends over 30 years recorded in the city of Granada, Spain.

stat.ME↗