Protein Adsorption on Lipid Monolayers at their Coexistence Region

R. R. Netz; D. Andelman; H. Orland

Home/Archive/arXiv

arXiv · cond-mat/9803262

Protein Adsorption on Lipid Monolayers at their Coexistence Region

R. R. Netz·D. Andelman·H. Orland

View original source ↗Read source document ↗Export metadata ↓

Abstract

We investigate theoretically the behavior of proteins as well as other large macromolecules which are incorporated into amphiphilic monolayers at the air-water interface. We assume the monolayer to be in the coexistence region of the ``main'' transition, where domains of the liquid condensed phase coexist with the liquid expanded background. Using a simple mean-field free energy accounting for the interactions between proteins and amphiphilic molecules, we obtain the spatial protein distribution with the following characteristics. When the proteins preferentially interact with either the liquid condensed or liquid expanded domains, they will be dissolved in the respective phase. When the proteins are energetically rather indifferent to the density of the amphiphiles, they will be localized at the line boundary between the (two-dimensional) liquid expanded and condensed phases. In between these two limiting cases, a delocalization transition of the proteins takes place. This transition is accessible by changing the temperature or the amount of incorporated protein. These findings are in agreement with recent fluorescence microscopy experiments. Our results also apply to lipid multicomponent membranes showing coexistence of distinct fluid phases.

Explore related subjects

cond-mat.soft q-bio

Keep this discovery

Explore connections, maps & timelines

BibTeX RIS

R. R. Netz, D. Andelman, H. Orland. 1998-03-21. Protein Adsorption on Lipid Monolayers at their Coexistence Region. https://arxiv.org/abs/cond-mat/9803262

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related papers

arXiv2026

Controlling microalgae populations by phototactic memory

Motile microorganisms navigate environments that vary in space and time by coupling sensory inputs to internal physiological states and active motion. In photosynthetic microorganisms, such coupling can be mediated by phototaxis, yet how temporal sensing combines with spatial variations of the environment to shape population organisation remains poorly understood. To probe this coupling, we expose populations of the phototactic microalga \textit{Chlamydomonas reinhardtii} to structured light landscapes. Under ring-shaped illumination, cells robustly accumulate at the center of the illuminated region, rather than at the light-intensity maximum. Single-cell tracking shows that cells steer relative to local intensity gradients and undergo a non-trivial phototactic response, where, on average, cells outside the ring perform positive phototaxis while cells inside perform negative phototaxis. Population experiments, numerical simulations and analytical modelling show that this trapping cannot be reproduced by an instantaneous switching rule, but requires a finite phototactic memory acting on the transition between positive and negative phototaxis. This internal timescale couples to the geometry of the light field and to the persistence of active motion, enabling controllable spatial localisation without physical confinement. Our results generically show how memory in a single-cell sensory response can control population-level organisation in a living active system.

cond-mat.soft↗

arXiv2026

Emergent odd response in active chiral films

Active chiral fluids can support an anomalous transport coefficient known as odd (or Hall) viscosity. Hydrodynamic descriptions of such fluids typically introduce odd viscosity phenomenologically. How such a response emerges from specific microscopic interactions remains incompletely understood. Here, building on classical shear rheology, we microscopically derive an odd rheological response in active chiral films: thin layers of torque-exerting, elongated particles anchored to a no-slip surface. A canonical realization of such a film is the bacterial carpet, in which flagellated bacteria are tethered head-down to a solid surface while their flagella remain free to spin and inject angular momentum into the surrounding fluid. Using a Smoluchowski kinetic theory for the orientational dynamics of these anchored particles, we derive their stress response to an imposed shear flow. We reveal that shear-induced reorientation leads to a flow-aligned polarization and a transverse surface traction from which the odd-viscosity tensor follows in closed form. This approach stands in contrast with existing microscopic theories, in which the axis of torque injection is insensitive to the flow rather than set by it. Numerical solutions of the kinetic theory further highlight saturation of the transverse traction at strong shear, driven by this orientation dynamics -- signaling departure from linear response. Our results demonstrate how odd viscosity can emerge self-consistently as a coarse-grained rheological signature of active fluid-structure interaction and establish active chiral films as a new controllable setting for odd hydrodynamics.

cond-mat.soft↗

arXiv2026

Inclined surfaces bias bacterial swarming expansion and edge organization

Bacterial swarming is the collective expansion of dense populations of motile cells across hydrated soft surfaces, yet gravity is usually treated as a fixed background condition in standard horizontal assays. We used surface inclination to examine how agar-surface orientation relative to gravity affects the expansion of Enterobacter sp. SM3 swarms. At macroscopic scales, we found that colony expansion depended non-monotonically on inclination, with the strongest spreading at intermediate inclinations and weaker expansion under shallow or near-inverted conditions. Paired up-facing acute and down-facing obtuse configurations with the same tilt magnitude showed different expansion responses, suggesting that swarm expansion depended on both tilt magnitude and which side of the agar surface faced upward relative to gravity. Inclination also produced downhill-biased colony morphologies. For microscopic scales, particle image velocimetry (PIV) analysis showed generally lower mean activity under inclination than in the flat references, with a non-monotonic angular response. The downhill tip showed slower motion, shorter spatial correlations and smaller vortex cores than the upper region. To interpret the macroscopic trends, we extended a two-phase thin-film model by introducing an effective gravity coupling projected normal and tangential to the agar surface. Simulations suggest that the surface-tangential component mainly drives lateral redistribution, whereas the surface-normal component modifies film pressure and helps distinguish up-facing from down-facing configurations.

cond-mat.soft↗