arXiv subjects

Alban Redheuil

Publications and source records attributed to Alban Redheuil.

3 recordsLinked to original sources

arXiv2026

CMDiff: Left Atrial Scar Segmentation from 3D LGE MRI Using Conditional Mask Diffusion Model: A Feasibility Study

Late gadolinium enhancement (LGE) cardiac MRI enables non-invasive assessment of left atrial (LA) scar, an imaging marker associated with atrial fibrillation ablation outcome. However, automatic scar segmentation is hindered by low contrast, the thin atrial wall, scarce labels, and extreme class imbalance. Conditional diffusion offers iterative mask generation, but its suitability for sparse 3D LA scar segmentation remains unclear. To address this gap, we propose Conditional Mask Diffusion (CMDiff), which predicts clean masks using a dynamic-encoder-conditioned 3D sinusoidal UNet. We compared CMDiff with a deterministic baseline on identical cases in five-fold cross-validation of 60 scar-labelled public LASCARQS subjects, with 48 training and 12 held-out cases per fold. CMDiff achieved a scar DSC of 0.47 $\pm$ 0.08, HD95 of 12.89 $\pm$ 6.39 mm, and ASD of 1.91 $\pm$ 0.96 mm, compared with deterministic baseline values of 0.51 $\pm$ 0.08, 10.86 $\pm$ 5.39 mm, and 1.58 $\pm$ 1.03 mm, respectively. Under the same implementation, clean-mask prediction performed substantially better than the noise-prediction configuration evaluated in this study. Thus, CMDiff was technically feasible but did not improve segmentation performance: DSC was lower, and both HD95 and ASD were higher. Direct mask diffusion therefore provides an analytical alternative, but not a competitive performance advance for this task. The source code is publicly available at https://github.com/jizhang02/CMDiff.

cs.CV↗

arXiv2026

Progressive Learning with Anatomical Priors for Reliable Left Atrial Scar Segmentation from Late Gadolinium Enhancement MRI

Cardiac MRI late gadolinium enhancement (LGE) enables non-invasive identification of left atrial (LA) scar, whose spatial distribution is strongly associated with atrial fibrillation (AF) severity and recurrence. However, automatic LA scar segmentation remains challenging due to low contrast, annotation variability, and the lack of anatomical constraints, often leading to non-reliable predictions. Accordingly, our aim was to propose a progressive learning strategy to segment LA scar from LGE images inspired from a clinical workflow. A 3-stage framework based on SwinUNETR was implemented, comprising: 1) a first LA cavity pre-learning model, 2) dual-task model which further learns spatial relationship between LA geometry and scar patterns, and 3) fine-tuning on precise segmentation of the scar. Furthermore, we introduced an anatomy-aware spatially weighted loss that incorporates prior clinical knowledge by constraining scar predictions to anatomically plausible LA wall regions while mitigating annotation bias. Our preliminary results obtained on validation LGE volumes from LASCARQS public dataset after 5-fold cross validation, LA segmentation had Dice score of 0.94, LA scar segmentation achieved Dice score of 0.50, Hausdorff Distance of 11.84 mm, Average Surface Distance of 1.80 mm, outperforming only a one-stage scar segmentation with 0.49, 13.02 mm, 1.96 mm, repectively. By explicitly embedding clinical anatomical priors and diagnostic reasoning into deep learning, the proposed approach improved the accuracy and reliability of LA scar segmentation from LGE, revealing the importance of clinically informed model design.

cs.CV↗

arXiv2021

Deep Learning-based Automated Aortic Area and Distensibility Assessment: The Multi-Ethnic Study of Atherosclerosis (MESA)

This study applies convolutional neural network (CNN)-based automatic segmentation and distensibility measurement of the ascending and descending aorta from 2D phase-contrast cine magnetic resonance imaging (PC-cine MRI) within the large MESA cohort with subsequent assessment on an external cohort of thoracic aortic aneurysm (TAA) patients. 2D PC-cine MRI images of the ascending and descending aorta at the pulmonary artery bifurcation from the MESA study were included. Train, validation, and internal test sets consisted of 1123 studies (24282 images), 374 studies (8067 images), and 375 studies (8069 images), respectively. An external test set of TAAs consisted of 37 studies (3224 images). A U-Net based CNN was constructed, and performance was evaluated utilizing dice coefficient (for segmentation) and concordance correlation coefficients (CCC) of aortic geometric parameters by comparing to manual segmentation and parameter estimation. Dice coefficients for aorta segmentation were 97.6% (CI: 97.5%-97.6%) and 93.6% (84.6%-96.7%) on the internal and external test of TAAs, respectively. CCC for comparison of manual and CNN maximum and minimum ascending aortic areas were 0.97 and 0.95, respectively, on the internal test set and 0.997 and 0.995, respectively, for the external test. CCCs for maximum and minimum descending aortic areas were 0.96 and 0. 98, respectively, on the internal test set and 0.93 and 0.93, respectively, on the external test set. We successfully developed and validated a U-Net based ascending and descending aortic segmentation and distensibility quantification model in a large multi-ethnic database and in an external cohort of TAA patients.

q-bio.QM↗