Alexander L. Van Slyke | Search arXiv

arXiv2026

Determination of the Human-Robot Interaction Workspace for Robot Assisted Head Stabilization Control

Accurate head immobilization is critical for medical procedures such as neuroimaging and intracranial radiation therapy, where even minor motion can compromise precision. Traditional methods, such as rigid stereotactic frames and thermoplastic face masks, are invasive, uncomfortable for patients, and require a time-consuming setup. To overcome these limitations, a novel approach employs a 6-degree-of-freedom (6DoF) robotic head holder that is integrated with real-time optical motion tracking, enabling dynamic compensation for head movements without physical restraint. However, implementing this system requires a detailed biomechanical understanding of skull-cervical spine interactions to define safe and effective motion limits. In this study, we conduct a human volunteer investigation using a 6DoF Stewart platform robot to characterize biokinematic workspace of the head-neck system and establish foundational data for human-robot interaction in precision head stabilization.

cs.RO↗

arXiv2021

Improving the efficiency of small animal 3D printed compensator IMRT with beamlet intensity total variation regularization

Purpose: There is growing interest in the use of modern 3D printing technology to implement intensity-modulated radiation therapy (IMRT) on the preclinical scale which is analogous to clinical IMRT. However, current 3D-printed IMRT methods suffer from complex modulation patterns leading to long delivery times, excess filament usage, and inaccurate compensator fabrication. In this work, we have developed a total variation regularization (TVR) approach to address these issues. Methods: TVR-IMRT, a technique designed to minimize the intensity difference between neighboring beamlets, was used to optimize the beamlet intensity map, which was then converted to corresponding compensator thicknesses in copper-doped PLA filament. IMRT and TVR-IMRT plans using five beams were generated to treat a mouse heart while sparing lung tissue. The individual field doses and composite dose were delivered to film and compared to the corresponding planned doses using gamma analysis. Results: TVR-IMRT reduced the total variation of both the beamlet intensities and compensator thicknesses by around 50% when compared to standard 3D printed compensator IMRT. The total mass of compensator material consumed and radiation beam-on time were reduced by 20-30%, while DVHs remained comparable. Gamma analysis passing rate with 3%/0.3mm criterion was 89.07% for IMRT and 95.37% for TVR-IMRT. Conclusion: TVR can be applied to small animal IMRT beamlet intensities in order to produce fluence maps and subsequent 3D-printed compensator patterns with less total variation, simplifying 3D printing and reducing the amount of filament required. The TVR-IMRT plan required less beam-on time while maintaining the dose conformity when compared to a traditional IMRT plan.

physics.med-ph↗