Search arXivSearch

arXiv subjects

Andy Chang

Publications and source records attributed to Andy Chang.

2 recordsLinked to original sources

AsmEvo: Agentic Assembly-Level Optimization of AMD GPU Kernels with Functional Equivalence Verification

High-performance ML systems increasingly rely on GPU kernels whose editable source is unavailable, generated, or too distant from final machine code to expose remaining optimizations. Existing LLM kernel optimizers and autotuners mainly operate on CUDA, Triton, HIP, or tensor-program source and validate against reference implementations. We study a stricter setting: optimizing an already compiled AMDGPU code object, where the deployed binary is the only behavioral oracle. We present AsmEvo, an agentic assembly-level optimizer for AMD GPU kernels. Given an AMDGPU code object K0, AsmEvo reconstructs a reassemblable representation, proposes low-level edits with a long-horizon agent, rebuilds an ABI-preserving optimized object, and accepts candidates only after differential verification against K0 under identical launches. AsmEvo combines code-object recovery, metadata-aware rebuilding, profiling-guided hot-window editing, correctness-gated timing, and conservative in-place patch fallback. We conduct extensive experiments with AsmEvo on various AMD GPU kernels. On MI308X, AsmEvo improves 29 of 30 selected KernelBench kernels, reaching 1.35x geometric-mean and 3.88x maximum speedup. On MI300X production workloads, it improves all evaluated AITer binaries and vLLM/SGLang Triton assembly kernels, reaching 1.09x/1.31x and 1.18x/1.34x geometric-mean/maximum speedups, respectively, while preserving functional equivalence.

cs.CL

Federated Semantic Knowledge Graphs for Laboratory Workflows: A Structured Expert Elicitation Methodology Demonstrated Through Bioanalytical Workflow Twins

Laboratory workflows in pharmaceutical and biomedical research encode substantial tacit knowledge -- expert judgment about failure conditions, decision branching logic, and contextual dependencies -- that remains inaccessible to protocol documents, sensor streams, and existing biomedical ontologies. We present a repeatable structured expert elicitation methodology and federated Semantic Knowledge Graph (SKG) architecture for capturing and querying this knowledge, demonstrated through deployment at the Biochemical and Cellular Pharmacology Department of Genentech. Knowledge is elicited via the Protocol Intelligence Co-pilot, a purpose-built AI interview agent that applies structured elicitation lenses to surface tacit procedural knowledge with expert-assigned confidence scores, producing graph representations across three tiers: program-level decision milestones, assay protocol knowledge, and physical execution infrastructure. Separately constructed subgraphs, exemplified by immunoassay (ELISA), quantitative mass spectrometry (LC-MS/PRM), and laboratory automation, are aligned through a shared upper ontology and queried as a single federated graph. Evaluation demonstrates seven query types structurally unavailable from any individual data source, including a cross-subgraph traversal that identifies automation-masked silent failures -- conditions where execution logs report success while scientific validity is compromised. Critically, the MASKED_BY graph relationship encodes a class of laboratory risk invisible to current informatics platforms -- the structural gap that prevents existing systems from reasoning about scientific validity. This architecture provides the semantic world model that AI laboratory agents currently lack: a queryable representation of where workflows fail silently, where human judgment is irreplaceable, and which execution assets mask rather than detect failure.

cs.DB