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Augusto Garcia-Agundez

Publications and source records attributed to Augusto Garcia-Agundez.

3 recordsLinked to original sources

Learning to Detect Shifts in Unstructured Data Streams via Monitoring-by-Betting

Continuous monitoring of generative AI systems requires detecting distribution shifts in the unstructured data they ingest and generate. Existing monitoring methods typically control false alarms by requiring the discrepancy measure used to detect shifts to be *pre-specified*. However, for unstructured data, pre-specification creates a sensitivity--breadth trade-off: a narrowly defined measure is sensitive to the anticipated shift but may miss unexpected changes, whereas a broadly defined measure may detect a wider range of shifts but with reduced sensitivity. Although adaptively hypothesizing the shift direction can overcome this limitation, such data-dependent adaptation generally invalidates conventional false-alarm guarantees. We reconcile adaptivity with statistical validity through testing-by-betting, reframing sequential changepoint detection as a betting game in which the bettor continually updates its hypothesized shift direction, or witness function, as new observations arrive. We introduce *asymptotic e-detectors*, which approximate the pre-change distribution using a calibration set of size $m$, and prove that they asymptotically control the average run length to a false alarm as $m$ increases. Empirically, calibration sets as small as $m=30$ provide effective control. We then develop adaptive monitoring strategies ranging from black-box bettors that learn from embeddings to interpretable bettors based on LLM-proposed concepts. Across three real-world datasets, including data from a clinical AI scribe deployment, adaptive monitors detect shifts faster than fixed monitors at the same false-alarm level. Further, when the true shifts are sparse and interpretable, LLM-concept monitors provide the fastest and most interpretable detection, while also guiding root-cause diagnosis for complex shifts.

cs.LG↗

The Minimum Information about CLinical Artificial Intelligence Checklist for Generative Modeling Research (MI-CLAIM-GEN)

Recent advances in generative models, including large language models (LLMs), vision language models (VLMs), and diffusion models, have accelerated the field of natural language and image processing in medicine and marked a significant paradigm shift in how biomedical models can be developed and deployed. While these models are highly adaptable to new tasks, scaling and evaluating their usage presents new challenges not addressed in previous frameworks. In particular, the ability of these models to produce useful outputs with little to no specialized training data ("zero-" or "few-shot" approaches), as well as the open-ended nature of their outputs, necessitate the development of new guidelines for robust reporting of clinical generative model research. In response to gaps in standards and best practices for the development of clinical AI tools identified by US Executive Order 141103 and several emerging national networks for clinical AI evaluation, we begin to formalize some of these guidelines by building on the original MI-CLAIM checklist. The new checklist, MI-CLAIM-GEN (Table 1), aims to address differences in training, evaluation, interpretability, and reproducibility of new generative models compared to non-generative ("predictive") AI models. This MI-CLAIM-GEN checklist also seeks to clarify cohort selection reporting with unstructured clinical data and adds additional items on alignment with ethical standards for clinical AI research.

cs.CL↗

When BERT Fails -- The Limits of EHR Classification

Transformers are powerful text representation learners, useful for all kinds of clinical decision support tasks. Although they outperform baselines on readmission prediction, they are not infallible. Here, we look into one such failure case, and report patterns that lead to inferior predictive performance.

cs.CL↗