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Axel Krieger

Publications and source records attributed to Axel Krieger.

At least 19 recordsLinked to original sources

Supervised Autonomous Bimanual Suction and Cauterization for Bleeding Control in Low Grade Splenic Trauma

Uncontrolled hemorrhage remains a leading cause of preventable trauma mortality. Timely intervention is not always available, making autonomous systems that can aid in bleeding control a promising alternative. Given the safety-critical nature of the task, supervised autonomy, in which the system executes the technical steps while a human retains oversight, represents a necessary intermediate step toward this goal. In this work, we present a supervised autonomous bimanual robotic framework for injury cauterization (eletrosurgical coagulation) in low-grade splenic trauma. The system integrates real-time bleeding segmentation, markerless tool keypoint tracking, and deep tool-tissue contact detection to coordinate two robotic arms for synchronized suction and cauterization. Evaluated on a novel, cannulated ex vivo splenic hemorrhage model, the system achieved an average bleeding surface cauterization coverage of 82.9% across seven distinct injuries. This work demonstrates the feasibility of using a supervised autonomous bimanual system to deliver targeted coagulation across an injury site.

cs.RO↗

Velocity Optimization via Thermal Imaging Enhances Autonomous Tumor Resection

Objective: To demonstrate and evaluate THERMO, a thermal-velocity optimization algorithm for autonomous electrosurgery, in ex vivo porcine tissue using the UR10e-based ASTR system. Methods: Thermography for Electrosurgical Rate Modulation via Optimization (ThERMO), a closed-loop algorithm that uses real-time thermal imaging data to minimize thermal injury while ensuring accurate cut margins, was tested on ex vivo porcine tissue. Histological analysis was performed to detect thermal injury extent at a cellular level, and 3D photogrammetric measurement was used to verify margin accuracy. ThERMO's performance was compared against two previously used fixed velocity methods. Results: ThERMO outperformed both fixed velocity comparison methods without requiring data-driven training or iterative tuning, reducing thermal injury by up to 52%, improving cut accuracy by up to 59%, and maintaining task completion speed. Conclusions: Closed-loop thermal feedback via ThERMO improves autonomous robotic electrosurgery by simultaneously reducing thermal injury and improving margin accuracy, reinforcing its value over fixed velocity approaches for tumor resection applications. Significance: This work advances autonomous robotic tumor resection by demonstrating that real-time closed-loop thermal feedback control can substantially reduce collateral tissue damage and improve surgical margin accuracy.

cs.RO↗

Current validation practice undermines surgical AI development

Surgical data science (SDS) is rapidly advancing, yet clinical adoption of artificial intelligence (AI) in surgery remains limited, with inadequate validation as an important contributing factor. Existing validation practices often neglect the temporal and hierarchical structure of intraoperative videos, yielding misleading or clinically irrelevant results. We introduce a comprehensive catalogue of validation pitfalls in AI-based surgical video analysis, derived from a multi-stage Delphi process with 92 international experts. Pitfalls span three categories: (1) data, (2) metric selection/configuration, and (3) aggregation and reporting. A systematic review of surgical AI papers reveals that these pitfalls are widespread. Experiments on surgical video datasets show that ignoring temporal and hierarchical data structures can understate uncertainty, obscure critical failure modes, and alter algorithm rankings. To address these shortcomings, we provide consensus-based best practices compiled. Together, this work provides an evidence-based framework for rigorous validation of surgical video analysis algorithms, guiding benchmarking, reporting, regulatory review, and clinical translation.

q-bio.OT↗

SurgVIL: Scaling Surgical Robot Imitation Learning with Open-source Surgical Videos

Learning-based surgical robot autonomy requires large-scale demonstrations with synchronized videos and robot actions, but such data are exceedingly rare in clinical or realistic tissue settings because robot kinematics are typically inaccessible outside controlled research systems. In contrast, phantom data collected on research platforms provide accurate action labels but lack the visual diversity of real tissue. We propose SurgVIL, a framework for scaling surgical robot imitation learning using open-source surgical videos. SurgVIL combines kinematically labeled phantom robot demonstrations with surgical videos from open-source datasets and online sources for policy learning. Since these videos lack robot motion labels, we estimate approximate kinematics as weak supervision. We evaluate SurgVIL on two da Vinci robot tasks: needle pick-up and cholecystectomy cutting. Across ACT, $π_0$, and GR00T-H backbones, adding surgical videos substantially improves generalization to real-tissue and out-of-distribution settings, suggesting a scalable path from phantom training toward generalizable surgical robot policies.

cs.RO↗

LEAP-NBV: Lightweight Edge Active-Perception for Foundation-Model Next-Best-View Planning

Foundation models are endowing autonomous systems with greater intelligence, enabling a more comprehensive understanding of the environment through visual perception. A representative example is Human Mesh Recovery (HMR), which provides useful estimates of a target's 3D pose and shape that can benefit tactical missions. However, the size and power demands of such models make them difficult to run on edge platforms and limit their real-time performance, undermining the requirements of tactical edge deployment - especially for active perception, where a mobile robot must plan its next-best view on-board and cannot offload computation under contested communications. We present LEAP-NBV, a lightweight active-perception framework that runs foundation-model-driven Next-Best-View (NBV) planning on-board an edge device. To this end, we distill a family of large HMR teachers, each into a compact 32M student, with an offline mesh objective, then quantize the vision encoder to FP16 and characterize its on-device accuracy and latency. Within an occlusion-aware active perception loop, we evaluate all configurations on the same held-out benchmark and deploy the end-to-end pipeline on an NVIDIA Jetson Xavier NX, reporting measured on-device latency and energy. Distillation recovers 6-7 mm of Procrustes-aligned mean per-vertex position error (PA-MPVPE) over the undistilled student on the test set. Selecting the edge-optimal compression model brings the HMR engine to ~12 ms at a small accuracy cost and runs the full closed loop at 3.6 FPS and 2.6 J per frame, achieving a 2.0x speedup and 3.0x lower energy than the uncompressed model while nearly matching downstream task quality.

cs.AI↗

Occupancy Network-Guided Autonomous Robotic Partial Nephrectomy

Autonomous soft-tissue cancer surgery has been limited to interventions on organ surfaces, because current systems cannot perceive and adapt to anatomy once it deforms or is cut. We introduce the first vision-guided autonomous system capable of performing complete tumor resections for partial nephrectomy. Our system integrates conditional occupancy networks, trained entirely in a physics-based simulation, that infer full 3-D anatomy (tumor, margin tissue, and kidney) from single-view partial point clouds. These occupancy networks maintain intraoperative tracking even as tissue is cut and deformed, enabling adaptive planning and execution. The surgical platform combines a depth camera for capturing surface point clouds, dual robotic arms for electrosurgical cutting and vacuum-based tissue manipulation, and an autonomous control strategy for tumor resection. In patient-derived hydrogel phantoms under an open partial nephrectomy setting, the robot performed eight consecutive autonomous tumor resections comprising 77 electrosurgical cuts, with all cuts achieving negative surgical margins and 1.61 $\pm$ 0.48 mm mean absolute margin error. This work demonstrates, for the first time, a foundation for supervised autonomous closed-loop, imaging-driven, margin-negative tumor removal in phantoms.

cs.RO↗

OA-NBV: Occlusion-Aware Next-Best-View Planning for Human-Centered Active Perception on Mobile Robots

We naturally step sideways or lean to see around the obstacle when our view is blocked, and recover a more informative observation. Enabling robots to make the same kind of viewpoint choice is critical for human-centered operations, including search, triage, and disaster response, where cluttered environments and partial visibility frequently degrade downstream perception. However, many Next-Best-View (NBV) methods primarily optimize generic exploration or long-horizon coverage, and do not explicitly target the immediate goal of obtaining a single usable observation of a partially occluded person under real motion constraints. We present Occlusion-Aware Next-Best-View Planning for Human-Centered Active Perception on Mobile Robots (OA-NBV), an occlusion-aware NBV pipeline that autonomously selects the next traversable viewpoint to obtain a more complete view of an occluded human. OA-NBV integrates perception and motion planning by scoring candidate viewpoints using a target-centric visibility model that accounts for occlusion, target scale, and target completeness, while restricting candidates to feasible robot poses. OA-NBV achieves over 90% success rate in both simulation and real-world trials, while baseline NBV methods degrade sharply under occlusion. Beyond success rate, OA-NBV improves observation quality: compared to the strongest baseline, it increases normalized target area by at least 81% and keypoint visibility by at least 58% across settings, making it a drop-in view-selection module for diverse human-centered downstream tasks.

cs.RO↗

AI-based single-shot structured-light depth reconstruction for real-time laparoscopic surgical guidance

Significance. Accurate intraoperative depth perception is important for autonomous and semi-autonomous robotic laparoscopic surgery. Conventional fringe projection profilometry can achieve millimeter-scale accuracy but often requires multi-shot acquisition, digital-micromirror-device projection, and projector-camera synchronization, complicating integration into compact laparoscopic systems. Aim. To develop a synchronization-free, single-shot depth-sensing platform using a passive LED-illuminated binary mask and a VQ-VAE prior with a custom U-Net depth head. Approach. A compact projection module was coupled to one channel of a dual-channel laparoscope, while the second channel imaged the fringe-illuminated target. A Zivid 3D camera acquired reference depth for 722 paired phantom images. Zivid depth maps were reprojected into the SSLE image frame for supervised training and evaluation. The VQ-VAE encoded each input into a discrete latent representation, and a latent-space U-Net predicted depth without a separate mask-prediction branch. Results. Using a fixed train/validation/test split, the proposed model achieved an MAE of 3.70 mm, AbsRel of 0.0326, delta=1.1 accuracy of 0.962, and delta=1.1^2 accuracy of 0.970. It achieved lower MAE than the dual U-Net MaskNet + DepthNet baseline and outperformed off-the-shelf monocular depth models in MAE, AbsRel, and threshold accuracy. The pipeline operated at 26.0 Hz over 301 consecutive frames on an NVIDIA A100 GPU. Conclusions. The LED-illuminated binary-pattern platform with latent-space depth reconstruction enables synchronization-free, video-rate endoscopic depth estimation. Results demonstrate Zivid-referenced phantom reconstruction without an explicit segmentation stage, while emphasizing the importance of dataset size and SSLE-Zivid calibration accuracy.

eess.IV↗

Toward Autonomous Soft Robotic Endovascular Navigation via Imitation Learning

In endovascular surgery, endovascular interventionists push a thin tube called a catheter, guided by a thin wire to a treatment site inside the patient's blood vessels to treat various conditions such as blood clots, aneurysms, and malformations. Robotic guidewires can enhance maneuverability but are difficult to model and control. Autonomous soft robotic guidewire navigation has the potential to overcome these challenges, increasing the precision and safety of endovascular navigation. As a first step, we establish a large-scale, 2D-projected environment for autonomous navigation. In other surgical domains, end-to-end imitation learning has shown promising results. Thus, we develop a transformer-based imitation learning framework with goal conditioning, relative action outputs, and automatic contrast dye injections to enable generalizable soft robot navigation in an aneurysm targeting task. We train the policy on 36 different modular bifurcated geometries, generating 647 total demonstrations under simulated fluoroscopy, and evaluate it on three previously unseen vascular geometries. The policy reaches the aneurysm with a success rate of 83% on the unseen geometries, outperforming several baselines. In addition, ablation and baseline studies evaluate the effectiveness of each design and data collection choice. Lastly, we extend the policy to achieve 75% success on an unseen patient-derived geometry. Project website: https://softrobotnavigation.github.io/

cs.RO↗

Investigating Robot Control Policy Learning for Autonomous X-ray-guided Spine Procedures

Imitation learning-based robot control policies are enjoying renewed interest in video-based robotics. However, it remains unclear whether this approach applies to X-ray-guided procedures, such as spine instrumentation, with sparse inputs. We examine the feasibility, opportunities and challenges for imitation policy learning in bi-plane-guided cannula insertion. We develop an in silico sandbox for scalable, automated simulation of X-ray-guided spine procedures with a high degree of realism. We curate a dataset of correct trajectories and corresponding bi-planar X-ray sequences that emulate the stepwise alignment of providers. We then train imitation learning policies for planning and open-loop control that iteratively align a cannula in a vertebroplasty setting solely based on visual information. This precisely controlled setup offers insights into limitations and capabilities of this method. Our policy succeeded on the first attempt in 68.5% of cases, maintaining safe intra-pedicular trajectories across diverse vertebral levels. The policy transferred to complex anatomy, including fractures, as well as varied anatomies and initializations. Rollouts on real X-ray indicate that partial sim-to-real transfer with plausible trajectories is possible. While these preliminary results are promising, we also identify limitations, especially in entry point precision. The current results present a clear benchmark for future efforts, while with more robust priors and domain knowledge, such models may provide a foundation for future efforts toward lightweight and CT-free robotic intra-operative spinal navigation.

cs.CV↗

Robust Autonomous Control of a Magnetic Millirobot in In Vitro Cardiac Flow

Untethered magnetic millirobots offer significant potential for minimally invasive cardiac therapies; however, achieving reliable autonomous control in pulsatile cardiac flow remains challenging. This work presents a vision-guided control framework enabling precise autonomous navigation of a magnetic millirobot in an in vitro heart phantom under physiologically relevant flow conditions. The system integrates UNet-based localization, A* path planning, and a sliding mode controller with a disturbance observer (SMC-DOB) designed for multi-coil electromagnetic actuation. Although drag forces are estimated using steady-state CFD simulations, the controller compensates for transient pulsatile disturbances during closed-loop operation. In static fluid, the SMC-DOB achieved sub-millimeter accuracy (root-mean-square error, RMSE = 0.49 mm), outperforming PID and MPC baselines. Under moderate pulsatile flow (7 cm/s peak, 20 cP), it reduced RMSE by 37% and peak error by 2.4$\times$ compared to PID. It further maintained RMSE below 2 mm (0.27 body lengths) under elevated pulsatile flow (10 cm/s peak, 20 cP) and under low-viscosity conditions (4.3 cP, 7 cm/s peak), where baseline controllers exhibited unstable or failed tracking. These results demonstrate robust closed-loop magnetic control under time-varying cardiac flow disturbances and support the feasibility of autonomous millirobot navigation for targeted drug delivery.

cs.RO↗

Task-Space Singularity Avoidance for Control Affine Systems Using Control Barrier Functions

Singularities in robotic and dynamical systems arise when the mapping from control inputs to task-space motion loses rank, leading to an inability to determine inputs. This limits the system's ability to generate forces and torques in desired directions and prevents accurate trajectory tracking. This paper presents a control barrier function (CBF) framework for avoiding such singularities in control-affine systems. Singular configurations are identified through the eigenvalues of a state-dependent input-output mapping matrix, and barrier functions are constructed to maintain a safety margin from rank-deficient regions. Conditions for theoretical guarantees on safety are provided as a function of actuator dynamics. Simulations on a planar 2-link manipulator and a magnetically actuated needle demonstrate smooth trajectory tracking while avoiding singular configurations and reducing control input spikes by up to 100x compared to the nominal controller.

cs.RO↗

AIMD-L: An automated laboratory for high-throughput characterization of structural materials for extreme environments

Rapid developments in artificial intelligence and machine learning as applied to materials science are creating an urgent need for experimental data, which can be provided by high-throughput and autonomous laboratories. To date most demonstrations of such laboratories have focused on functional materials, with less attention paid to structural materials. We present here the Artificial Intelligence in Materials Design Laboratory (AIMD-L), an automated, high-throughput facility for characterizing the microstructure and properties of structural metals and ceramics, with an emphasis on materials in extreme environments. AIMD-L has two custom instruments for characterization of structural materials: HELIX for shock studies of materials, and MAXIMA for X-ray diffraction and X-ray fluorescence spectroscopy. Specifically designed for high-throughput studies, HELIX and MAXIMA are each capable of collecting data at rates two to three orders of magnitude faster than conventional systems. A third experimental station, SPHINX, is a commercial nanoindenter modified for integration into the automated workflow of AIMD-L. A user (which may be human or an AI agent) directs the experiments to be carried out by means of a centralized control program. The experimental stations are linked by a conveyance that moves samples around the lab, with a robot at each station for sample transfer in/out of the instrument. The experimental stations also communicate with a common data layer that streams data autonomously from each instrument to a data portal, where their arrival triggers automated workflows for data reduction and analysis. The processed data are immediately available to the human operator or agentic AI, forming a closed loop for rapid decision-making and experimental control.

cond-mat.mtrl-sci↗

Modeling and Control of a Pneumatic Soft Robotic Catheter Using Neural Koopman Operators

Catheter-based interventions are widely used for the diagnosis and treatment of cardiac diseases. Recently, robotic catheters have attracted attention for their ability to improve precision and stability over conventional manual approaches. However, accurate modeling and control of soft robotic catheters remain challenging due to their complex, nonlinear behavior. The Koopman operator enables lifting the original system data into a linear "lifted space", offering a data-driven framework for predictive control; however, manually chosen basis functions in the lifted space often oversimplify system behaviors and degrade control performance. To address this, we propose a neural network-enhanced Koopman operator framework that jointly learns the lifted space representation and Koopman operator in an end-to-end manner. Moreover, motivated by the need to minimize radiation exposure during X-ray fluoroscopy in cardiac ablation, we investigate open-loop control strategies using neural Koopman operators to reliably reach target poses without continuous imaging feedback. The proposed method is validated in two experimental scenarios: interactive position control and a simulated cardiac ablation task using an atrium-like cavity. Our approach achieves average errors of 2.1 +- 0.4 mm in position and 4.9 +- 0.6 degrees in orientation, outperforming not only model-based baselines but also other Koopman variants in targeting accuracy and efficiency. These results highlight the potential of the proposed framework for advancing soft robotic catheter systems and improving catheter-based interventions.

cs.RO↗

Assessing Hemodynamic Impact of Tissue-Engineered Vascular Graft Displacement: Combining Postoperative in vivo Results and Computational Modeling to Improve Surgical Planning

Tissue-engineered vascular grafts (TEVG) have shown promise in advancing vascular reconstructions. However, precise in vivo implantation is challenging, and it is unclear how deviations in location and size affect hemodynamics. This study aims to compare preoperative designs and postoperative anatomies of TEVG in an in vivo study to evaluate discrepancies and investigate the impact of graft displacement and size on hemodynamics by virtually simulating implantation scenarios that are informed by in vivo postoperative results. Designed and postoperative geometries of four porcine aortas were compared to measure the mismatch in implantation location and graft shape. These results informed a virtual TEVG implantation study. TEVG location, orientation, and size were varied to investigate the effects on the final aorta shape and hemodynamics. Anastomosis of TEVG was simulated using finite element modeling. Key hemodynamic metrics were obtained from virtual implantations and actual postoperative anatomies using computational fluid dynamics. Our in vivo study showed that TEVGs can experience up to 6.9 mm displacement and a 38 degree rotational shift post-implantation, leading to discrepancies in pressure drop (2.5 mmHg, 50%) and time-averaged wall shear stress (7.2 Pa, 72%) compared to predictions. Virtual anastomosis simulations improved aortic shape predictions by 27.5%. Our results highlight the sensitivity of key hemodynamic metrics to graft implantation location and size mismatch. By quantifying displacement ranges and their impacts during surgery, surgeons can make informed decisions.

physics.med-ph↗

Fluoroscopy-Constrained Magnetic Robot Control via Zernike-Based Field Modeling and Nonlinear MPC

Magnetic actuation enables surgical robots to navigate complex anatomical pathways while reducing tissue trauma and improving surgical precision. However, clinical deployment is limited by the challenges of controlling such systems under fluoroscopic imaging, which provides low frame rate and noisy pose feedback. This paper presents a control framework that remains accurate and stable under such conditions by combining a nonlinear model predictive control (NMPC) framework that directly outputs coil currents, an analytically differentiable magnetic field model based on Zernike polynomials, and a Kalman filter to estimate the robot state. Experimental validation is conducted with two magnetic robots in a 3D-printed fluid workspace and a spine phantom replicating drug delivery in the epidural space. Results show the proposed control method remains highly accurate when feedback is downsampled to 3 Hz with added Gaussian noise (sigma = 2 mm), mimicking clinical fluoroscopy. In the spine phantom experiments, the proposed method successfully executed a drug delivery trajectory with a root mean square (RMS) position error of 1.18 mm while maintaining safe clearance from critical anatomical boundaries.

cs.RO↗

A Mobile Magnetic Manipulation Platform for Gastrointestinal Navigation with Deep Reinforcement Learning Control

Targeted drug delivery in the gastrointestinal (GI) tract using magnetic robots offers a promising alternative to systemic treatments. However, controlling these robots is a major challenge. Stationary magnetic systems have a limited workspace, while mobile systems (e.g., coils on a robotic arm) suffer from a "model-calibration bottleneck", requiring complex, pre-calibrated physical models that are time-consuming to create and computationally expensive. This paper presents a compact, low-cost mobile magnetic manipulation platform that overcomes this limitation using Deep Reinforcement Learning (DRL). Our system features a compact four-electromagnet array mounted on a UR5 collaborative robot. A Soft Actor-Critic (SAC)-based control strategy is trained through a sim-to-real pipeline, enabling effective policy deployment within 15 minutes and significantly reducing setup time. We validated the platform by controlling a 7-mm magnetic capsule along 2D trajectories. Our DRL-based controller achieved a root-mean-square error (RMSE) of 1.18~mm for a square path and 1.50~mm for a circular path. We also demonstrated successful tracking over a clinically relevant, 30 cm * 20 cm workspace. This work demonstrates a rapidly deployable, model-free control framework capable of precise magnetic manipulation in a large workspace,validated using a 2D GI phantom.

cs.RO↗

AURA-CVC: Autonomous Ultrasound-guided Robotic Assistance for Central Venous Catheterization

Purpose: Central venous catheterization (CVC) is a critical medical procedure for vascular access, hemodynamic monitoring, and life-saving interventions. Its success remains challenging due to the need for continuous ultrasound-guided visualization of a target vessel and approaching needle, which is further complicated by anatomical variability and operator dependency. Errors in needle placement can lead to life-threatening complications. While robotic systems offer a potential solution, achieving full autonomy remains challenging. In this work, we propose an end-to-end robotic-ultrasound-guided CVC pipeline, from scan initialization to needle insertion. Methods: We introduce a deep-learning model to identify clinically relevant anatomical landmarks from a depth image of the patient's neck, obtained using RGB-D camera, to autonomously define the scanning region and paths. Then, a robot motion planning framework is proposed to scan, segment, reconstruct, and localize vessels (veins and arteries), followed by the identification of the optimal insertion zone. Finally, a needle guidance module plans the insertion under ultrasound guidance with operator's feedback. This pipeline was validated on a high-fidelity commercial phantom across 10 simulated clinical scenarios. Results: The proposed pipeline achieved 10 out of 10 successful needle placements on the first attempt. Vessels were reconstructed with a mean error of 2.15 \textit{mm}, and autonomous needle insertion was performed with an error less than or close to 1 \textit{mm}. Conclusion: To our knowledge, this is the first robotic CVC system demonstrated on a high-fidelity phantom with integrated planning, scanning, and insertion. Experimental results show its potential for clinical translation.

cs.RO↗