arXiv subjects

Changqing Gong

Publications and source records attributed to Changqing Gong.

5 recordsLinked to original sources

arXiv2026

Cross-Task Generalization in Handwriting-Based Alzheimer's Screening via Vision Language Adaptation

Alzheimer's disease (AD) is a prevalent neurodegenerative disorder for which early detection is critical. Handwriting, which can be disrupted by subtle motor and cognitive decline, provides a non-invasive and cost-effective window for AD screening. Existing handwriting-based AD studies mostly rely on online trajectories and hand-crafted features, while the influence of handwriting task type on diagnostic performance and cross-task generalization remains underexplored. Meanwhile, large-scale vision--language models have demonstrated strong transfer and adaptation ability in natural-image anomaly detection and several medical modalities, such as chest X-ray and brain MRI. However, handwriting-based disease detection remains unexplored within this paradigm. To address this gap, we introduce a lightweight Cross-Layer Fusion Adapter (CLFA) framework that repurposes Contrastive Language--Image Pre-training (CLIP) for handwriting-based AD screening. CLFA inserts multi-level adapters into a frozen visual encoder, combining cross-layer feature fusion with depthwise 2D convolution on patch grids to capture both local stroke irregularities and higher-level handwriting structure. This design progressively aligns pretrained vision--language representations with AD-related handwriting cues and supports transfer from supervised source tasks to task-disjoint unseen target tasks. On the Darwin dataset, under the subject-disjoint cross-task protocol, averaged over all 600 task-disjoint source-target pairs, CLFA achieves 74.63\% AUC, 74.85\% accuracy, and 73.72\% F1 score, outperforming the best competing model by 2.15, 1.79, and 1.87 percentage points, respectively.

cs.CV↗

arXiv2026

Segment-Level Risk Discovery in Online Handwriting for Alzheimer's Disease Detection

Online handwriting provides a non-invasive and low-cost behavioral biomarker for Alzheimer's disease (AD) detection, as it reflects both cognitive planning and fine motor control. Existing handwriting-based AD detection methods usually rely on global trajectory features or whole-sample representations, which can be strongly affected by individual writing style, task-specific variation, and acquisition noise. In this paper, we propose NormPaST-Risk, a healthy-normative Paper-Air selective trajectory state-space risk network for interpretable AD detection from online handwriting. Instead of treating the entire trajectory as a single holistic representation, our method reformulates AD handwriting detection as local disease-relevant segment discovery. Specifically, a multi-scale temporal encoder captures stroke dynamics at different temporal resolutions, while a selective Paper-Air state-space encoder models long-range handwriting progression and distinguishes on-paper motor execution from in-air planning and transition behaviors. To explicitly characterize abnormal deviations, a healthy normative branch learns normal handwriting dynamics from healthy controls, and a task-aware multi-expert segment-risk module estimates segment-level AD risk calibrated by hidden-state changes and normative deviations. A weakly supervised segment-level objective further enables high-risk segment discovery without manual segment annotations. Experiments on the DARWIN benchmark demonstrate that the proposed framework achieves superior AD/HC classification performance compared with existing methods. Moreover, the discovered high-risk segments can be projected back to the original handwriting trajectory, providing interpretable evidence associated with AD-related handwriting variations.

cs.CV↗

arXiv2024

Hybrid Transformer for Early Alzheimer's Detection: Integration of Handwriting-Based 2D Images and 1D Signal Features

Alzheimer's Disease (AD) is a prevalent neurodegenerative condition where early detection is vital. Handwriting, often affected early in AD, offers a non-invasive and cost-effective way to capture subtle motor changes. State-of-the-art research on handwriting, mostly online, based AD detection has predominantly relied on manually extracted features, fed as input to shallow machine learning models. Some recent works have proposed deep learning (DL)-based models, either 1D-CNN or 2D-CNN architectures, with performance comparing favorably to handcrafted schemes. These approaches, however, overlook the intrinsic relationship between the 2D spatial patterns of handwriting strokes and their 1D dynamic characteristics, thus limiting their capacity to capture the multimodal nature of handwriting data. Moreover, the application of Transformer models remains basically unexplored. To address these limitations, we propose a novel approach for AD detection, consisting of a learnable multimodal hybrid attention model that integrates simultaneously 2D handwriting images with 1D dynamic handwriting signals. Our model leverages a gated mechanism to combine similarity and difference attention, blending the two modalities and learning robust features by incorporating information at different scales. Our model achieved state-of-the-art performance on the DARWIN dataset, with an F1-score of 90.32\% and accuracy of 90.91\% in Task 8 ('L' writing), surpassing the previous best by 4.61% and 6.06% respectively.

cs.CV↗

arXiv2020

Quantum Ciphertext Dimension Reduction Scheme for Homomorphic Encrypted Data

At present, in the face of the huge and complex data in cloud computing, the parallel computing ability of quantum computing is particularly important. Quantum principal component analysis algorithm is used as a method of quantum state tomography. We perform feature extraction on the eigenvalue matrix of the density matrix after feature decomposition to achieve dimensionality reduction, proposed quantum principal component extraction algorithm (QPCE). Compared with the classic algorithm, this algorithm achieves an exponential speedup under certain conditions. The specific realization of the quantum circuit is given. And considering the limited computing power of the client, we propose a quantum homomorphic ciphertext dimension reduction scheme (QHEDR), the client can encrypt the quantum data and upload it to the cloud for computing. And through the quantum homomorphic encryption scheme to ensure security. After the calculation is completed, the client updates the key locally and decrypts the ciphertext result. We have implemented a quantum ciphertext dimensionality reduction scheme implemented in the quantum cloud, which does not require interaction and ensures safety. In addition, we have carried out experimental verification on the QPCE algorithm on IBM's real computing platform, and given a simple example of executing hybrid quantum circuits in the cloud to verify the correctness of our scheme. Experimental results show that the algorithm can perform ciphertext dimension reduction safely and effectively.

quant-ph↗

arXiv2020

Quantum k-means algorithm based on Trusted server in Quantum Cloud Computing

We propose a quantum k-means algorithm based on quantum cloud computing that effectively solves the problem that the client can not afford to execute the same quantum subroutine repeatedly in the face of large training samples. In the quantum k-means algorithm, the core subroutine is the Quantum minimization algorithm (GroverOptim), the client needs to repeat several Grover searches to find the minimum value in each iteration to find a new clustering center, so we use quantum homomorphic encryption scheme (QHE) to encrypt the data and upload it to the cloud for computing. After calculation, the server returns the calculation result to the client. The client uses the key to decrypt to get the plaintext result. It reduces the computing pressure for the client to repeat the same operation. In addition, when executing in the cloud, the key update of T-gate in the server is inevitable and complex. Therefore, this paper also proposes a T-gate update scheme based on trusted server in quantum ciphertext environment. In this scheme, the server is divided into trusted server and semi-trusted server. The semi-trusted server completes the calculation operation, and when the T-gate is executed in the circuit, the trusted server assists the semi-trusted server to calculate the T-gate, and then randomly generates a key and uploads it to the semi-trusted server. The trusted server assists the client to complete the key update operation, which once again reduces the pressure on the client and improves the efficiency of the quantum homomorphic encryption scheme. And on the basis of this scheme, the experiment is given by using IBM Qiskit to give the subroutine of quantum k-means. The experimental results show that the scheme can realize the corresponding computing function on the premise of ensuring security.

quant-ph↗