arXiv subjects

Chen Zhao

Publications and source records attributed to Chen Zhao.

At least 127 records · Page 7Linked to original sources

arXiv2026

New energy conversion system based on charge-exchange and inner-shell electron transitions

The rapidly growing demand for compact, high-energy power sources has outpaced the capabilities of conventional electrochemical systems that rely on outer-shell redox reactions. In this work, we present a new energy platform that utilizes inner-shell electron transitions that are previously inaccessible due to their high energy thresholds. By leveraging charge exchange processes between bare argon ions (Ar^18+) and neutral helium atoms, we provide clear evidence for the emission of soft X-ray and extreme-ultraviolet photons across a broad spectra range, resulting from inner-shell electron capture and cascade de-excitation. This strategy overcomes the limitations of radiative recombination by enhancing photon energy utilization through broader emission profiles more compatible with practical energy converters. Our design of a helium-filled chamber design enables precise control of output via pressure tuning, achieving a remarkable radiation power density of 6.29*10^8 W L^-1 and an unprecedented energy density of 2.64*10^6 Wh kg^-1. These results may provide a new and effective paradigm for energy conversion systems with ultra-high power and energy densities based on inner-shell electrons.

physics.atom-ph↗

arXiv2026

Histopathology-centered Computational Evolution of Spatial Omics: Integration, Mapping, and Foundation Models

Spatial omics (SO) technologies enable spatially resolved molecular profiling, while hematoxylin and eosin (H&E) imaging remains the gold standard for morphological assessment in clinical pathology. Recent computational advances increasingly place H&E images at the center of SO analysis, bridging morphology with transcriptomic, proteomic, and other spatial molecular modalities, and pushing resolution toward the single-cell level. In this survey, we systematically review the computational evolution of SO from a histopathology-centered perspective and organize existing methods into three paradigms: integration, which jointly models paired multimodal data; mapping, which infers molecular profiles from H&E images; and foundation models, which learn generalizable representations from large-scale spatial datasets. We analyze how the role of H&E images evolves across these paradigms from spatial context to predictive anchor and ultimately to representation backbone in response to practical constraints such as limited paired data and increasing resolution demands. We further summarize actionable modeling directions enabled by current architectures and delineate persistent gaps driven by data, biology, and technology that are unlikely to be resolved by model design alone. Together, this survey provides a histopathology-centered roadmap for developing and applying computational frameworks in SO.

q-bio.GN↗

arXiv2026

A Large Scale Empirical Analysis on the Adherence Gap between Standards and Tools in SBOM

A Software Bill of Materials (SBOM) is a machine-readable artifact that systematically organizes software information, enhancing supply chain transparency and security. To facilitate the exchange and utilization of SBOMs, organizations such as the Linux Foundation and OWASP have proposed SBOM standards. Following standards, organizations have developed tools for generating and utilizing SBOMs. However, limited research has examined the adherence of these SBOM tools to standard specifications, a gap that could lead to compliance failures and disruptions in SBOM utilization. This paper presents the first large-scale, two-stage empirical analysis of the adherence gap, using our automated evaluation framework, SAP. The evaluation, comprising a baseline evaluation and a one-year longitudinal follow-up, covers 55,444 SBOMs generated by six SBOM tools from 3,287 real-world repositories. Our analysis reveals persistent, fundamental limitations in current SBOM tools: (1) inadequate compliance support with policy requirements; (2) poor tool consistencies, including inter-tool consistency rates as low as 7.84% to 12.77% for package detection across languages, and significant longitudinal inconsistency, where tools show low consistency with their own prior versions; and (3) mediocre to poor accuracy for detailed software information, e.g., accuracy of package licenses below 20%. We analyze the root causes of these gaps and provide practical solutions. All the code, replication docker image, evaluation results are open sourced at [GitHub](https://github.com/dw763j/SAP) and [Zenodo](https://doi.org/10.5281/zenodo.14998624) for further researches.

cs.SE↗

arXiv2026

YOLO-IOD: Towards Real Time Incremental Object Detection

Current methods for incremental object detection (IOD) primarily rely on Faster R-CNN or DETR series detectors; however, these approaches do not accommodate the real-time YOLO detection frameworks. In this paper, we first identify three primary types of knowledge conflicts that contribute to catastrophic forgetting in YOLO-based incremental detectors: foreground-background confusion, parameter interference, and misaligned knowledge distillation. Subsequently, we introduce YOLO-IOD, a real-time Incremental Object Detection (IOD) framework that is constructed upon the pretrained YOLO-World model, facilitating incremental learning via a stage-wise parameter-efficient fine-tuning process. Specifically, YOLO-IOD encompasses three principal components: 1) Conflict-Aware Pseudo-Label Refinement (CPR), which mitigates the foreground-background confusion by leveraging the confidence levels of pseudo labels and identifying potential objects relevant to future tasks. 2) Importancebased Kernel Selection (IKS), which identifies and updates the pivotal convolution kernels pertinent to the current task during the current learning stage. 3) Cross-Stage Asymmetric Knowledge Distillation (CAKD), which addresses the misaligned knowledge distillation conflict by transmitting the features of the student target detector through the detection heads of both the previous and current teacher detectors, thereby facilitating asymmetric distillation between existing and newly introduced categories. We further introduce LoCo COCO, a more realistic benchmark that eliminates data leakage across stages. Experiments on both conventional and LoCo COCO benchmarks show that YOLO-IOD achieves superior performance with minimal forgetting.

cs.CV↗

arXiv2025

Anatomy Guided Coronary Artery Segmentation from CCTA Using Spatial Frequency Joint Modeling

Accurate coronary artery segmentation from coronary computed tomography angiography is essential for quantitative coronary analysis and clinical decision support. Nevertheless, reliable segmentation remains challenging because of small vessel calibers, complex branching, blurred boundaries, and myocardial interference. We propose a coronary artery segmentation framework that integrates myocardial anatomical priors, structure aware feature encoding, and three dimensional wavelet inverse wavelet transformations. Myocardial priors and residual attention based feature enhancement are incorporated during encoding to strengthen coronary structure representation. Wavelet inverse wavelet based downsampling and upsampling enable joint spatial frequency modeling and preserve multi scale structural consistency, while a multi scale feature fusion module integrates semantic and geometric information in the decoding stage. The model is trained and evaluated on the public ImageCAS dataset using a 3D overlapping patch based strategy with a 7:1:2 split for training, validation, and testing. Experimental results demonstrate that the proposed method achieves a Dice coefficient of 0.8082, Sensitivity of 0.7946, Precision of 0.8471, and an HD95 of 9.77 mm, outperforming several mainstream segmentation models. Ablation studies further confirm the complementary contributions of individual components. The proposed method enables more stable and consistent coronary artery segmentation under complex geometric conditions, providing reliable segmentation results for subsequent coronary structure analysis tasks.

cs.CV↗

arXiv2025

Capillary Filling Dynamics in Polygonal Tubes

We study the dynamics of capillary filling in tubes of regular polygon cross-section. Using Onsager variational principle, we derive a coupled ordinary differential equation and partial differential equation, which respectively describe time evolution of the bulk flow and the saturation profile of the finger flow. We obtain both numerical solution and self-similar solution to the coupled equations, and the results indicate that the bulk flow and the finger flow both follow the $t^{1/2}$ time-scaling. We show that due to the coupling effect of the finger flow, the prefactor for the bulk flow is smaller than that of the Lucas-Washburn prediction. The reduction effect is more pronounced when the side number $n$ of the regular-polygon is small, while as $n$ increases, the prefactor approaches Lucas-Washburn prediction.

physics.flu-dyn↗

arXiv2025

Blood Pressure Prediction for Coronary Artery Disease Diagnosis using Coronary Computed Tomography Angiography

Computational fluid dynamics (CFD) based simulation of coronary blood flow provides valuable hemodynamic markers, such as pressure gradients, for diagnosing coronary artery disease (CAD). However, CFD is computationally expensive, time-consuming, and difficult to integrate into large-scale clinical workflows. These limitations restrict the availability of labeled hemodynamic data for training AI models and hinder broad adoption of non-invasive, physiology based CAD assessment. To address these challenges, we develop an end to end pipeline that automates coronary geometry extraction from coronary computed tomography angiography (CCTA), streamlines simulation data generation, and enables efficient learning of coronary blood pressure distributions. The pipeline reduces the manual burden associated with traditional CFD workflows while producing consistent training data. We further introduce a diffusion-based regression model designed to predict coronary blood pressure directly from CCTA derived features, bypassing the need for slow CFD computation during inference. Evaluated on a dataset of simulated coronary hemodynamics, the proposed model achieves state of the art performance, with an R2 of 64.42%, a root mean squared error of 0.0974, and a normalized RMSE of 0.154, outperforming several baseline approaches. This work provides a scalable and accessible framework for rapid, non-invasive blood pressure prediction to support CAD diagnosis.

cs.CV↗

arXiv2025

JT-DA: Enhancing Data Analysis with Tool-Integrated Table Reasoning Large Language Models

In this work, we present JT-DA-8B (JiuTian Data Analyst 8B), a specialized large language model designed for complex table reasoning tasks across diverse real-world scenarios. To address the lack of high-quality supervision in tabular reasoning scenarios, we construct a comprehensive and diverse training corpus with 34 well-defined table reasoning tasks, by aggregating 29 public table QA datasets and 3 million tables. An automatic pipeline is proposed to generate realistic multi-step analytical tasks involving reasoning patterns. The model is trained upon open-source JT-Coder-8B model, an 8B-parameter decoder-only foundation model trained from scratch. In the training stage, we leverage LLM-based scoring and workflow-aligned filtering to distill high-quality, table-centric data. Both supervised fine-tuning (SFT) and Reinforcement learning (RL) are adopted to optimize our model. Afterwards, a four-stage table reasoning workflow is proposed, including table preprocessing, table sensing, tool-integrated reasoning, and prompt engineering, to improve model interpretability and execution accuracy. Experimental results show that JT-DA-8B achieves strong performance in various table reasoning tasks, demonstrating the effectiveness of data-centric generation and workflow-driven optimization.

cs.AI↗

arXiv2025

An Analysis of Large Language Models for Simulating User Responses in Surveys

Using Large Language Models (LLMs) to simulate user opinions has received growing attention. Yet LLMs, especially trained with reinforcement learning from human feedback (RLHF), are known to exhibit biases toward dominant viewpoints, raising concerns about their ability to represent users from diverse demographic and cultural backgrounds. In this work, we examine the extent to which LLMs can simulate human responses to cross-domain survey questions through direct prompting and chain-of-thought prompting. We further propose a claim diversification method CLAIMSIM, which elicits viewpoints from LLM parametric knowledge as contextual input. Experiments on the survey question answering task indicate that, while CLAIMSIM produces more diverse responses, both approaches struggle to accurately simulate users. Further analysis reveals two key limitations: (1) LLMs tend to maintain fixed viewpoints across varying demographic features, and generate single-perspective claims; and (2) when presented with conflicting claims, LLMs struggle to reason over nuanced differences among demographic features, limiting their ability to adapt responses to specific user profiles.

cs.CL↗

arXiv2025

UG-FedDA: Uncertainty-Guided Federated Domain Adaptation for Multi-Center Alzheimer's Disease Detection

Alzheimer's disease (AD) is an irreversible neurodegenerative disorder, and early diagnosis is critical for timely intervention. However, most existing classification frameworks face challenges in multicenter studies, as they often neglect inter-site heterogeneity and lack mechanisms to quantify uncertainty, which limits their robustness and clinical applicability. To address these issues, we proposed Uncertainty-Guided Federated Domain Adaptation (UG-FedDA), a novel multicenter AD classification framework that integrates uncertainty quantification (UQ) with federated domain adaptation to handle cross-site structure magnetic resonance imaging (MRI) heterogeneity under privacy constraints. Our approach extracts multi-template region-of-interest (RoI) features using a self-attention transformer, capturing both regional representations and their interactions. UQ is integrated to guide feature alignment, mitigating source-target distribution shifts by down-weighting uncertain samples. Experiments are conducted on three public datasets: the Alzheimer's Disease Neuroimaging Initiative (ADNI), the Australian Imaging, Biomarkers and Lifestyle study (AIBL), and the Open Access Series of Imaging Studies (OASIS). UG-FedDA achieved consistent cross-domain improvements in accuracy, sensitivity, and area under the ROC curve across three classification tasks: AD vs. normal controls (NC), mild cognitive impairment (MCI) vs. AD, and NC vs. MCI. For NC vs. AD, UG-FedDA achieves accuracies of 90.54%, 89.04%, and 77.78% on ADNI, AIBL and OASIS datasets, respectively. For MCI vs. AD, accuracies are 80.20% (ADNI), 71.91% (AIBL), and 79.73% (OASIS). For NC vs. MCI, results are 76.87% (ADNI), 73.91% (AIBL), and 83.73% (OASIS). These results demonstrate that the proposed framework not only adapts efficiently across multiple sites but also preserves strict privacy.

cs.CV↗

arXiv2025

Temporally Compressed 3D Gaussian Splatting for Dynamic Scenes

Recent advancements in high-fidelity dynamic scene reconstruction have leveraged dynamic 3D Gaussians and 4D Gaussian Splatting for realistic scene representation. However, to make these methods viable for real-time applications such as AR/VR, gaming, and rendering on low-power devices, substantial reductions in memory usage and improvements in rendering efficiency are required. While many state-of-the-art methods prioritize lightweight implementations, they struggle in handling {scenes with complex motions or long sequences}. In this work, we introduce Temporally Compressed 3D Gaussian Splatting (TC3DGS), a novel technique designed specifically to effectively compress dynamic 3D Gaussian representations. TC3DGS selectively prunes Gaussians based on their temporal relevance and employs gradient-aware mixed-precision quantization to dynamically compress Gaussian parameters. In addition, TC3DGS exploits an adapted version of the Ramer-Douglas-Peucker algorithm to further reduce storage by interpolating Gaussian trajectories across frames. Our experiments on multiple datasets demonstrate that TC3DGS achieves up to 67$\times$ compression with minimal or no degradation in visual quality. More results and videos are provided in the supplementary. Project Page: https://ahmad-jarrar.github.io/tc-3dgs/

cs.CV↗

arXiv2025

QiMeng-Kernel: Macro-Thinking Micro-Coding Paradigm for LLM-Based High-Performance GPU Kernel Generation

Developing high-performance GPU kernels is critical for AI and scientific computing, but remains challenging due to its reliance on expert crafting and poor portability. While LLMs offer promise for automation, both general-purpose and finetuned LLMs suffer from two fundamental and conflicting limitations: correctness and efficiency. The key reason is that existing LLM-based approaches directly generate the entire optimized low-level programs, requiring exploration of an extremely vast space encompassing both optimization policies and implementation codes. To address the challenge of exploring an intractable space, we propose Macro Thinking Micro Coding (MTMC), a hierarchical framework inspired by the staged optimization strategy of human experts. It decouples optimization strategy from implementation details, ensuring efficiency through high-level strategy and correctness through low-level implementation. Specifically, Macro Thinking employs reinforcement learning to guide lightweight LLMs in efficiently exploring and learning semantic optimization strategies that maximize hardware utilization. Micro Coding leverages general-purpose LLMs to incrementally implement the stepwise optimization proposals from Macro Thinking, avoiding full-kernel generation errors. Together, they effectively navigate the vast optimization space and intricate implementation details, enabling LLMs for high-performance GPU kernel generation. Comprehensive results on widely adopted benchmarks demonstrate the superior performance of MTMC on GPU kernel generation in both accuracy and running time. On KernelBench, MTMC achieves near 100% and 70% accuracy at Levels 1-2 and 3, over 50% than SOTA general-purpose and domain-finetuned LLMs, with up to 7.3x speedup over LLMs, and 2.2x over expert-optimized PyTorch Eager kernels. On the more challenging TritonBench, MTMC attains up to 59.64% accuracy and 34x speedup.

cs.DC↗

arXiv2025

SkillGen: Learning Domain Skills for In-Context Sequential Decision Making

Large language models (LLMs) are increasingly applied to sequential decision-making through in-context learning (ICL), yet their effectiveness is highly sensitive to prompt quality. Effective prompts should meet three principles: focus on decision-critical information, provide step-level granularity, and minimize reliance on expert annotations through label efficiency. However, existing ICL methods often fail to satisfy all three criteria simultaneously. Motivated by these challenges, we introduce SkillGen, a skill-based ICL framework for structured sequential reasoning. It constructs an action-centric, domain-level graph from sampled trajectories, identifies high-utility actions via temporal-difference credit assignment, and retrieves step-wise skills to generate fine-grained, context-aware prompts. We further present a theoretical analysis showing that focusing on high-utility segments supports task identifiability and informs more effective ICL prompt design. Experiments on ALFWorld, BabyAI, and ScienceWorld, using both open-source and proprietary LLMs, show that SkillGen achieves consistent gains, improving progress rate by 5.9%-16.5% on average across models.

cs.AI↗

arXiv2025

Fair In-Context Learning via Latent Concept Variables

The emerging in-context learning (ICL) ability of large language models (LLMs) has prompted their use for predictive tasks in various domains with different data types, including tabular data, facilitated by serialization methods. However, with increasing applications in high-stakes domains, it has been shown that LLMs can inherit social bias and discrimination from their pre-training data. In this work, we investigate inherent bias in LLMs during in-context learning with tabular data. We focus on an optimal demonstration selection approach that utilizes latent concept variables for resource-efficient task adaptation. We design data augmentation strategies that reduce the correlation between predictive outcomes and sensitive variables, helping promote fairness during latent concept learning. We utilize the learned concept to select demonstrations and obtain fair predictions. The latent concept variables are learned using a smaller internal LLM and generalized to larger external LLMs. We empirically verify that the fair latent variable approach improves fairness results on tabular datasets compared to multiple heuristic demonstration selection methods.

cs.LG↗

arXiv2025

Out-of-Distribution Detection with Positive and Negative Prompt Supervision Using Large Language Models

Out-of-distribution (OOD) detection is committed to delineating the classification boundaries between in-distribution (ID) and OOD images. Recent advances in vision-language models (VLMs) have demonstrated remarkable OOD detection performance by integrating both visual and textual modalities. In this context, negative prompts are introduced to emphasize the dissimilarity between image features and prompt content. However, these prompts often include a broad range of non-ID features, which may result in suboptimal outcomes due to the capture of overlapping or misleading information. To address this issue, we propose Positive and Negative Prompt Supervision, which encourages negative prompts to capture inter-class features and transfers this semantic knowledge to the visual modality to enhance OOD detection performance. Our method begins with class-specific positive and negative prompts initialized by large language models (LLMs). These prompts are subsequently optimized, with positive prompts focusing on features within each class, while negative prompts highlight features around category boundaries. Additionally, a graph-based architecture is employed to aggregate semantic-aware supervision from the optimized prompt representations and propagate it to the visual branch, thereby enhancing the performance of the energy-based OOD detector. Extensive experiments on two benchmarks, CIFAR-100 and ImageNet-1K, across eight OOD datasets and five different LLMs, demonstrate that our method outperforms state-of-the-art baselines.

cs.CV↗

arXiv2025

Robust Dynamic Coded Distributed Storage with Partially Storage Constrained Servers

We consider the problem of Robust Dynamic Coded Distributed Storage (RDCDS) with partially storage constrained servers where the goal is to enable robust (resilient to server dropouts) and efficient (as measured by the communication costs) read and update operations, subject to the constraint that the storage at $S$ out of $N$ servers is limited by $1/K_c$ the size of the message. Building upon previously established converse arguments and achievability schemes by Jia et al., in this work we develop a set of new converse arguments and coding designs that enable us to completely characterize the fundamental limits of RDCDS with partially storage constrained servers, i.e., the minimum number of available servers for feasible update operation and the minimum communication costs for read and update operations across various server dropout scenarios.

cs.IT↗

arXiv2025

Exploring the Feasibility of End-to-End Large Language Model as a Compiler

In recent years, end-to-end Large Language Model (LLM) technology has shown substantial advantages across various domains. As critical system software and infrastructure, compilers are responsible for transforming source code into target code. While LLMs have been leveraged to assist in compiler development and maintenance, their potential as an end-to-end compiler remains largely unexplored. This paper explores the feasibility of LLM as a Compiler (LaaC) and its future directions. We designed the CompilerEval dataset and framework specifically to evaluate the capabilities of mainstream LLMs in source code comprehension and assembly code generation. In the evaluation, we analyzed various errors, explored multiple methods to improve LLM-generated code, and evaluated cross-platform compilation capabilities. Experimental results demonstrate that LLMs exhibit basic capabilities as compilers but currently achieve low compilation success rates. By optimizing prompts, scaling up the model, and incorporating reasoning methods, the quality of assembly code generated by LLMs can be significantly enhanced. Based on these findings, we maintain an optimistic outlook for LaaC and propose practical architectural designs and future research directions. We believe that with targeted training, knowledge-rich prompts, and specialized infrastructure, LaaC has the potential to generate high-quality assembly code and drive a paradigm shift in the field of compilation.

cs.LG↗

arXiv2025

Fine-Tuning Vision-Language Models for Multimodal Polymer Property Prediction

Vision-Language Models (VLMs) have shown strong performance in tasks like visual question answering and multimodal text generation, but their effectiveness in scientific domains such as materials science remains limited. While some machine learning methods have addressed specific challenges in this field, there is still a lack of foundation models designed for broad tasks like polymer property prediction using multimodal data. In this work, we present a multimodal polymer dataset to fine-tune VLMs through instruction-tuning pairs and assess the impact of multimodality on prediction performance. Our fine-tuned models, using LoRA, outperform unimodal and baseline approaches, demonstrating the benefits of multimodal learning. Additionally, this approach reduces the need to train separate models for different properties, lowering deployment and maintenance costs.

cs.LG↗