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Daniel Moyer

Publications and source records attributed to Daniel Moyer.

At least 19 recordsLinked to original sources

Backbone-Informed Adaptation after EEG Pretraining: A Capacity-Controlled Study

Electroencephalography (EEG) foundation models learn representations that combine information across channels and time. This structure motivates adapters that model the same relationships during downstream learning. However, it is not clear whether such a design outperforms other candidate adapters. Moreover, in order to arrive at a fair comparison between candidate adapters, we also need to consider their trainable parameters. Here, we ask whether a backbone-informed (native) adapter makes better use of a given capacity by comparing it against a token-wise multilayer perceptron control that transforms each feature vector independently. We approximately match their trainable parameter counts and keep the pretrained encoder fixed. Across two EEG foundation models and tasks covering emotion recognition, sleep staging, and EEG event classification, the native adapter shows no consistent advantage. For one backbone, differences between the designs are small relative to variation across runs. For the other, the token-wise control performs better on emotion recognition and EEG event classification. On sleep staging, the native adapter's advantage over the token-wise control is reduced when we also train the component that processes sequences of EEG segments. The relative performance of the two adapters depends on the backbone, task, and downstream training protocol. These findings motivate evaluating backbone-informed adapters against capacity-matched alternatives.

cs.LG↗

Directionally Factorized Illumination with Spherical Harmonic Rotation

Many real-world capture scenarios involve an active light source rigidly attached to the camera: camera flashes for dark-environment imaging, underwater vehicle lights, and endoscopic/laparoscopic medical procedures. As the camera moves, the co-mounted light moves with it, causing the illumination direction at each surface point to change across views. Neural rendering methods (NeRF, Gaussian Splatting) encode this pose-dependent illumination as surface coloration, producing appearance inconsistencies and making it harder to recover the underlying scene. We present \textbf{DaFISH}, which can be plugged into any novel-view synthesis (NVS) pipeline such as NeRF. It factorizes per-point emitted color into surface albedo and a spherical harmonic (SH)-represented illumination factor. During training, the SH illumination is evaluated directly, enabling stable joint optimization of albedo, lighting, and geometry. \textbf{DaFISH} provides analytical generalization of illumination to arbitrary camera poses without retraining. Building on the closed-form SH-to-irradiance conversion, the training pipeline is fully differentiable from SH evaluation through volume rendering. Averaged over the held-out frames of the five scenes, \textbf{DaFISH} attains the best mean PSNR (38.91\,dB), SSIM (0.9613), and LPIPS (0.0582) among all compared methods. It improves over the strongest splatting baseline as well as the closest NeRF-based baseline, while recovering the scene consistently across views compared to prior methods.

cs.CV↗

Identify then Realize: Contrastive Learning of Latent Port-Hamiltonian Dynamics from Partial Observations

Identifying latent state representations and dynamics is essential when direct modeling in observation space is infeasible, particularly under partial and high-dimensional observations. In such settings, representation learning and physics-aware modeling are inherently coupled. We propose CIPHER, a two-stage identify-then-realize framework for learning latent port-Hamiltonian models of conservative and dissipative systems. First, a contrastive teacher jointly learns an encoder and a neural ODE to obtain predictive state representations from observation histories. Second, a student learns an invertible nonlinear coordinate transformation and port-Hamiltonian dynamics by matching encoded observed futures. We establish sufficient conditions for recovering the physical state up to a diffeomorphism and realizing its dynamics in port-Hamiltonian form. Across ten clean and noisy datasets, CIPHER is competitive with or outperforms state-of-the-art baselines by improving long-horizon forecast on complex systems. Further studies show robustness to over-specified latent dimensions and additional predictive gains from pH parameterization.

cs.LG↗

Differentiable Mesh State Estimation via Factor Graph Inference for Deformable Object Reconstruction

Estimating deformable object states remains a fundamental challenge in robotics and simulation. We propose a novel factor graph-based framework for probabilistic mesh state estimation of deformable objects. The method directly updates a tetrahedral mesh, a rich and physically-grounded representation of an environment, by combining physics priors, noisy sensor measurements, and temporal smoothness constraints within a unified probabilistic formulation. The estimation problem is posed as a nonlinear least-squares optimization and solved using Levenberg-Marquardt. Ex vivo central-airway obstruction experiments and simulations on deforming cube models demonstrate reliable and accurate reconstruction under both rigid motion and deformation, highlighting the potential of this probabilistic approach for principled, measurement-driven mesh state estimation in deformable object reconstruction.

cs.RO↗

Dataset-Dependent Effects of Cross-Depth Aggregation and Soft-Routed Experts in EEG Foundation Model Fine-Tuning

EEG decoding tasks can rely on different temporal dynamics and cross-channel relationships. We test whether specialized modules improve a fully fine-tuned EEG foundation model by augmenting CBraMod with cross-depth Attention Residuals (AttnRes) and two soft-routed expert banks. Across matched three-seed experiments on FACED, ISRUC, SEED-V, and PhysioNet-MI, the complete model changes mean balanced accuracy relative to full fine-tuning by -0.12, +1.27, +0.77, and -1.27 points, respectively. AttnRes alone improves mean balanced accuracy on three datasets, whereas adding experts on top of AttnRes helps only FACED and SEED-V. These gains come with substantial overhead: AttnRes requires 2.11 to 2.88x runtime and 1.78 to 2.67x memory, while the complete model requires 2.41 to 3.04x runtime and 1.86 to 2.85x memory. Overall, the added modules produce dataset-dependent, sometimes opposing effects rather than consistent gains over full fine-tuning.

cs.LG↗

Generalization and Memorization in Rectified Flow

Generative models based on the Flow Matching objective, particularly Rectified Flow, have emerged as a dominant paradigm for efficient, high-fidelity image synthesis. However, while existing research heavily prioritizes generation quality and architectural scaling, the underlying dynamics of how RF models memorize training data remain largely underexplored. In this paper, we systematically investigate the memorization behaviors of RF through the test statistics of Membership Inference Attacks (MIA). We progressively formulate three test statistics, culminating in a complexity-calibrated metric that successfully decouples intrinsic image spatial complexity from genuine memorization signals. This calibration yields a significant performance surge -- boosting attack AUC by up to 15% and the privacy-critical TPR@1%FPR metric by up to 45% -- establishing the first non-trivial MIA specifically tailored for RF. Leveraging these refined metrics, we uncover a distinct temporal pattern: under standard uniform temporal training, a model's susceptibility to MIA strictly peaks at the integration midpoint, a phenomenon we justify via the network's forced deviation from linear approximations. Finally, we demonstrate that substituting uniform timestep sampling with a Symmetric Exponential (U-shaped) distribution effectively minimizes exposure to vulnerable intermediate timesteps. Extensive evaluations across three datasets confirm that this temporal regularization suppresses memorization while preserving generative fidelity.

cs.LG↗

Score-based Membership Inference on Diffusion Models

Membership inference attacks (MIAs) against Diffusion Models (DMs) raise pressing privacy concerns by revealing whether a sample was part of the training set. While existing methods typically rely on measuring reconstruction error across multiple denoising steps as a test statistic, they often incur significant computational overhead. In this work, we present a simple yet successful attack statistic using only the predicted noise vectors from the DM's denoiser, or equivalently, the score. Specifically, we show that the expected denoiser output points toward a kernel-weighted local mean of nearby training samples, such that its norm encodes proximity to the training set and thereby reveals membership. Building on this observation, we propose SimA, a single-query attack that provides a principled, efficient alternative to existing multi-query methods. SimA consistently achieves highly competitive performance across variants of DMs and the Latent Diffusion Models (LDMs) on eight different datasets. Its Monte Carlo variant (SimA-MC) exhibits state-of-the-art performance in most experiments at 30 samples, significantly outperforming baseline methods in terms of TPR@1%FPR. These results demonstrate that complex reconstruction trajectories are unnecessary for effective membership inference, establishing SimA as a highly efficient benchmark for auditing privacy in DMs and LDMs.

cs.LG↗

IntraStyler: Intra-Domain Style Synthesis for Cross-Modality MRI Domain Adaptation

Segmentation of vestibular schwannoma and cochlea from T2 MRI is clinically important yet annotation-intensive. Domain adaptation (DA) has been widely adopted to bridge the gap between labeled contrast-enhanced T1 and unlabeled T2 datasets. While existing methods focus on cross-domain alignment, intra-domain variability within the target domain remains largely overlooked. Images from the same domain may vary substantially due to different scanners, field strengths, and acquisition protocols. Ignoring this variability produces homogeneous synthetic images that limit the generalizability of downstream segmentation models. To address this, we propose IntraStyler, a 3D unpaired image translation method that automatically discovers fine-grained intra-domain styles without any predefined sub-domains, and synthesizes diverse target domain images using per-image style references. To this end, we design a 3D style encoder trained with a novel contrastive learning objective to extract style-only embeddings disentangled from anatomy. IntraStyler is built upon the 1st place CrossMoDA challenge solution and further advances it, generating more diverse synthetic data and achieving more reliable downstream segmentation. Code is available at https://github.com/MedICL-VU/IntraStyler.

cs.CV↗

Harmonization mitigates diffusion MRI scanner effects in infancy: insights from the HEALthy Brain and Childhood Development (HBCD) study

The HEALthy Brain and Childhood Development (HBCD) Study is an ongoing longitudinal initiative to understand population-level brain maturation; however, large-scale studies must overcome site-related variance and preserve biologically relevant signal. In addition to diffusion-weighted magnetic resonance imaging images, the HBCD dataset offers analysis-ready derivatives for scientists to conduct their analysis, including scalar diffusion tensor (DTI) metrics in a predetermined set of bundles. The purpose of this study is to characterize HBCD-specific site effects in diffusion MRI data, which have not been systematically reported. In this work, we investigate the sensitivity of HBCD bundle metrics to scanner model-related variance and address these variations with ComBat-GAM harmonization within the current HBCD data release 1.1 across six scanner models. Following ComBat-GAM, we observe zero statistically significant differences between the distributions from any scanner model following FDR correction and reduce Cohen's f effect sizes across all metrics. Our work underscores the importance of rigorous harmonization efforts in large-scale studies, and we encourage future investigations of HBCD data to control for these effects.

eess.IV↗

Latent Diffusion Inversion Requires Understanding the Latent Space

The recovery of training data from generative models ("model inversion") has been extensively studied for diffusion models in the data domain as a memorization/overfitting phenomenon. Latent diffusion models (LDMs), which operate on the latent codes from encoder/decoder pairs, have been robust to prior inversion methods. In this work we describe two key findings: (1) the diffusion model exhibits non-uniform memorization across latent codes, tending to overfit samples located in high-distortion regions of the decoder pullback metric; (2) even within a single latent code, memorization contributions are unequal across representation dimensions. Our proposed method to ranks latent dimensions by their contribution to the decoder pullback metric, which in turn identifies dimensions that contribute to memorization. For score-based membership inference, a sub-task of model inversion, we find that removing less-memorizing dimensions improves performance on all tested methods and datasets, with average AUROC gains of 1-4% and substantial increases in TPR@1%FPR (1-32%) across diverse datasets including CIFAR-10, CelebA, ImageNet-1K, Pokemon, MS-COCO, and Flickr. Our results highlight the overlooked influence of the auto-encoder geometry on LDM memorization and provide a new perspective for analyzing privacy risks in diffusion-based generative models.

cs.LG↗

Personalized White Matter Bundle Segmentation for Early Childhood

White matter segmentation methods from diffusion magnetic resonance imaging range from streamline clustering-based approaches to bundle mask delineation, but none have proposed a pediatric-specific approach. We hypothesize that a deep learning model with a similar approach to TractSeg will improve similarity between an algorithm-generated mask and an expert-labeled ground truth. Given a cohort of 56 manually labelled white matter bundles, we take inspiration from TractSeg's 2D UNet architecture, and we modify inputs to match bundle definitions as determined by pediatric experts, evaluation to use k fold cross validation, the loss function to masked Dice loss. We evaluate Dice score, volume overlap, and volume overreach of 16 major regions of interest compared to the expert labeled dataset. To test whether our approach offers statistically significant improvements over TractSeg, we compare Dice voxels, volume overlap, and adjacency voxels with a Wilcoxon signed rank test followed by false discovery rate correction. We find statistical significance across all bundles for all metrics with one exception in volume overlap. After we run TractSeg and our model, we combine their output masks into a 60 label atlas to evaluate if TractSeg and our model combined can generate a robust, individualized atlas, and observe smoothed, continuous masks in cases that TractSeg did not produce an anatomically plausible output. With the improvement of white matter pathway segmentation masks, we can further understand neurodevelopment on a population level scale, and we can produce reliable estimates of individualized anatomy in pediatric white matter diseases and disorders.

eess.IV↗

Enhanced Landmark Detection Model in Pelvic Fluoroscopy using 2D/3D Registration Loss

Automated landmark detection offers an efficient approach for medical professionals to understand patient anatomic structure and positioning using intra-operative imaging. While current detection methods for pelvic fluoroscopy demonstrate promising accuracy, most assume a fixed Antero-Posterior view of the pelvis. However, orientation often deviates from this standard view, either due to repositioning of the imaging unit or of the target structure itself. To address this limitation, we propose a novel framework that incorporates 2D/3D landmark registration into the training of a U-Net landmark prediction model. We analyze the performance difference by comparing landmark detection accuracy between the baseline U-Net, U-Net trained with Pose Estimation Loss, and U-Net fine-tuned with Pose Estimation Loss under realistic intra-operative conditions where patient pose is variable.

cs.CV↗

Regression-based Pelvic Pose Initialization for Fast and Robust 2D/3D Pelvis Registration

This paper presents an approach for improving 2D/3D pelvis registration in optimization-based pose estimators using a learned initialization function. Current methods often fail to converge to the optimal solution when initialized naively. We find that even a coarse initializer greatly improves pose estimator accuracy, and improves overall computational efficiency. This approach proves to be effective also in challenging cases under more extreme pose variation. Experimental validation demonstrates that our method consistently achieves robust and accurate registration, enhancing the reliability of 2D/3D registration for clinical applications.

cs.CV↗

Fully Differentiable dMRI Streamline Propagation in PyTorch

Diffusion MRI (dMRI) provides a distinctive means to probe the microstructural architecture of living tissue, facilitating applications such as brain connectivity analysis, modeling across multiple conditions, and the estimation of macrostructural features. Tractography, which emerged in the final years of the 20th century and accelerated in the early 21st century, is a technique for visualizing white matter pathways in the brain using dMRI. Most diffusion tractography methods rely on procedural streamline propagators or global energy minimization methods. Although recent advancements in deep learning have enabled tasks that were previously challenging, existing tractography approaches are often non-differentiable, limiting their integration in end-to-end learning frameworks. While progress has been made in representing streamlines in differentiable frameworks, no existing method offers fully differentiable propagation. In this work, we propose a fully differentiable solution that retains numerical fidelity with a leading streamline algorithm. The key is that our PyTorch-engineered streamline propagator has no components that block gradient flow, making it fully differentiable. We show that our method matches standard propagators while remaining differentiable. By translating streamline propagation into a differentiable PyTorch framework, we enable deeper integration of tractography into deep learning workflows, laying the foundation for a new category of macrostructural reasoning that is not only computationally robust but also scientifically rigorous.

eess.IV↗

Pedicle Screw Pairing and Registration for Screw Pose Estimation from Dual C-arm Images Using CAD Models

Accurate matching of pedicle screws in both anteroposterior (AP) and lateral (LAT) images is critical for successful spinal decompression and stabilization during surgery. However, establishing screw correspondence, especially in LAT views, remains a significant clinical challenge. This paper introduces a method to address pedicle screw correspondence and pose estimation from dual C-arm images. By comparing screw combinations, the approach demonstrates consistent accuracy in both pairing and registration tasks. The method also employs 2D-3D alignment with screw CAD 3D models to accurately pair and estimate screw pose from dual views. Our results show that the correct screw combination consistently outperforms incorrect pairings across all test cases, even prior to registration. After registration, the correct combination further enhances alignment between projections and images, significantly reducing projection error. This approach shows promise for improving surgical outcomes in spinal procedures by providing reliable feedback on screw positioning.

cs.CV↗

Brain age identification from diffusion MRI synergistically predicts neurodegenerative disease

Estimated brain age from magnetic resonance image (MRI) and its deviation from chronological age can provide early insights into potential neurodegenerative diseases, supporting early detection and implementation of prevention strategies. Diffusion MRI (dMRI) presents an opportunity to build an earlier biomarker for neurodegenerative disease prediction because it captures subtle microstructural changes that precede more perceptible macrostructural changes. However, the coexistence of macro- and micro-structural information in dMRI raises the question of whether current dMRI-based brain age estimation models are leveraging the intended microstructural information or if they inadvertently rely on the macrostructural information. To develop a microstructure-specific brain age, we propose a method for brain age identification from dMRI that mitigates the model's use of macrostructural information by non-rigidly registering all images to a standard template. Imaging data from 13,398 participants across 12 datasets were used for the training and evaluation. We compare our brain age models, trained with and without macrostructural information mitigated, with an architecturally similar T1-weighted (T1w) MRI-based brain age model and two recent, popular, openly available T1w MRI-based brain age models that primarily use macrostructural information. We observe difference between our dMRI-based brain age and T1w MRI-based brain age across stages of neurodegeneration, with dMRI-based brain age being older than T1w MRI-based brain age in participants transitioning from cognitively normal (CN) to mild cognitive impairment (MCI), but younger in participants already diagnosed with Alzheimer's disease (AD). Furthermore, dMRI-based brain age may offer advantages over T1w MRI-based brain age in predicting the transition from CN to MCI up to five years before diagnosis.

cs.CV↗

NeuroBOLT: Resting-state EEG-to-fMRI Synthesis with Multi-dimensional Feature Mapping

Functional magnetic resonance imaging (fMRI) is an indispensable tool in modern neuroscience, providing a non-invasive window into whole-brain dynamics at millimeter-scale spatial resolution. However, fMRI is constrained by issues such as high operation costs and immobility. With the rapid advancements in cross-modality synthesis and brain decoding, the use of deep neural networks has emerged as a promising solution for inferring whole-brain, high-resolution fMRI features directly from electroencephalography (EEG), a more widely accessible and portable neuroimaging modality. Nonetheless, the complex projection from neural activity to fMRI hemodynamic responses and the spatial ambiguity of EEG pose substantial challenges both in modeling and interpretability. Relatively few studies to date have developed approaches for EEG-fMRI translation, and although they have made significant strides, the inference of fMRI signals in a given study has been limited to a small set of brain areas and to a single condition (i.e., either resting-state or a specific task). The capability to predict fMRI signals in other brain areas, as well as to generalize across conditions, remain critical gaps in the field. To tackle these challenges, we introduce a novel and generalizable framework: NeuroBOLT, i.e., Neuro-to-BOLD Transformer, which leverages multi-dimensional representation learning from temporal, spatial, and spectral domains to translate raw EEG data to the corresponding fMRI activity signals across the brain. Our experiments demonstrate that NeuroBOLT effectively reconstructs unseen resting-state fMRI signals from primary sensory, high-level cognitive areas, and deep subcortical brain regions, achieving state-of-the-art accuracy with the potential to generalize across varying conditions and sites, which significantly advances the integration of these two modalities.

eess.IV↗

Training Noise Token Pruning

In the present work we present Training Noise Token (TNT) Pruning for vision transformers. Our method relaxes the discrete token dropping condition to continuous additive noise, providing smooth optimization in training, while retaining discrete dropping computational gains in deployment settings. We provide theoretical connections to Rate-Distortion literature, and empirical evaluations on the ImageNet dataset using ViT and DeiT architectures demonstrating TNT's advantages over previous pruning methods.

cs.CV↗