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Dengdeng Yu

Publications and source records attributed to Dengdeng Yu.

8 recordsLinked to original sources

Conformalized Fairness via Quantile Regression

Algorithmic fairness has received increased attention in socially sensitive domains. While rich literature on mean fairness has been established, research on quantile fairness remains sparse but vital. To fulfill great needs and advocate the significance of quantile fairness, we propose a novel framework to learn a real-valued quantile function under the fairness requirement of Demographic Parity with respect to sensitive attributes, such as race or gender, and thereby derive a reliable fair prediction interval. Using optimal transport and functional synchronization techniques, we establish theoretical guarantees of distribution-free coverage and exact fairness for the induced prediction interval constructed by fair quantiles. A hands-on pipeline is provided to incorporate flexible quantile regressions with an efficient fairness adjustment post-processing algorithm. We demonstrate the superior empirical performance of this approach on several benchmark datasets. Our results show the model's ability to uncover the mechanism underlying the fairness-accuracy trade-off in a wide range of societal and medical applications.

stat.ML

Word Embeddings via Causal Inference: Gender Bias Reducing and Semantic Information Preserving

With widening deployments of natural language processing (NLP) in daily life, inherited social biases from NLP models have become more severe and problematic. Previous studies have shown that word embeddings trained on human-generated corpora have strong gender biases that can produce discriminative results in downstream tasks. Previous debiasing methods focus mainly on modeling bias and only implicitly consider semantic information while completely overlooking the complex underlying causal structure among bias and semantic components. To address these issues, we propose a novel methodology that leverages a causal inference framework to effectively remove gender bias. The proposed method allows us to construct and analyze the complex causal mechanisms facilitating gender information flow while retaining oracle semantic information within word embeddings. Our comprehensive experiments show that the proposed method achieves state-of-the-art results in gender-debiasing tasks. In addition, our methods yield better performance in word similarity evaluation and various extrinsic downstream NLP tasks.

cs.CL

Multivariate functional responses low rank regression with an application to brain imaging data

We propose a multivariate functional responses low rank regression model with possible high dimensional functional responses and scalar covariates. By expanding the slope functions on a set of sieve basis, we reconstruct the basis coefficients as a matrix. To estimate these coefficients, we propose an efficient procedure using nuclear norm regularization. We also derive error bounds for our estimates and evaluate our method using simulations. We further apply our method to the Human Connectome Project neuroimaging data to predict cortical surface motor task-evoked functional magnetic resonance imaging signals using various clinical covariates to illustrate the usefulness of our results.

stat.ME

Mapping the Genetic-Imaging-Clinical Pathway with Applications to Alzheimer's Disease

Alzheimer's disease is a progressive form of dementia that results in problems with memory, thinking, and behavior. It often starts with abnormal aggregation and deposition of beta amyloid and tau, followed by neuronal damage such as atrophy of the hippocampi, leading to Alzheimer's Disease (AD). The aim of this paper is to map the genetic-imaging-clinical pathway for AD in order to delineate the genetically regulated brain changes that drive disease progression based on the Alzheimer's Disease Neuroimaging Initiative (ADNI) dataset. We develop a novel two-step approach to delineate the association between high-dimensional 2D hippocampal surface exposures and the Alzheimer's Disease Assessment Scale (ADAS) cognitive score, while taking into account the ultra-high dimensional clinical and genetic covariates at baseline. Analysis results suggest that the radial distance of each pixel of both hippocampi is negatively associated with the severity of behavioral deficits conditional on observed clinical and genetic covariates. These associations are stronger in Cornu Ammonis region 1 (CA1) and subiculum subregions compared to Cornu Ammonis region 2 (CA2) and Cornu Ammonis region 3 (CA3) subregions.

stat.AP

Nonparametric principal subspace regression

In scientific applications, multivariate observations often come in tandem with temporal or spatial covariates, with which the underlying signals vary smoothly. The standard approaches such as principal component analysis and factor analysis neglect the smoothness of the data, while multivariate linear or nonparametric regression fail to leverage the correlation information among multivariate response variables. We propose a novel approach named nonparametric principal subspace regression to overcome these issues. By decoupling the model discrepancy, a simple and general two-step framework is introduced, which leaves much flexibility in choice of model fitting. We establish theoretical property of the general framework, and offer implementation procedures that fulfill requirements and enjoy the theoretical guarantee. We demonstrate the favorable finite-sample performance of the proposed method through simulations and a real data application from an electroencephalogram study.

math.ST

An Alternative Approach to Functional Linear Partial Quantile Regression

Functional data such as curves and surfaces have become more and more common with modern technological advancements. The use of functional predictors remains challenging due to its inherent infinite-dimensionality. The common practice is to project functional data into a finite dimensional space. The popular partial least square (PLS) method has been well studied for the functional linear model [1]. As an alternative, quantile regression provides a robust and more comprehensive picture of the conditional distribution of a response when it is non-normal, heavy-tailed, or contaminated by outliers. While partial quantile regression (PQR) was proposed in [2], no theoretical guarantees were provided due to the iterative nature of the algorithm and the non-smoothness of quantile loss function. To address these issues, we propose an alternative PQR (APQR) formulation with guaranteed convergence. This novel formulation motivates new theories and allows us to establish asymptotic properties. Numerical studies on a benchmark dataset show the superiority of our new approach. We also apply our novel method to a functional magnetic resonance imaging (fMRI) data to predict attention deficit hyperactivity disorder (ADHD) and a diffusion tensor imaging (DTI) dataset to predict Alzheimer's disease (AD).

math.ST

Sparse Wavelet Estimation in Quantile Regression with Multiple Functional Predictors

In this manuscript, we study quantile regression in partial functional linear model where response is scalar and predictors include both scalars and multiple functions. Wavelet basis are adopted to better approximate functional slopes while effectively detect local features. The sparse group lasso penalty is imposed to select important functional predictors while capture shared information among them. The estimation problem can be reformulated into a standard second-order cone program and then solved by an interior point method. We also give a novel algorithm by using alternating direction method of multipliers (ADMM) which was recently employed by many researchers in solving penalized quantile regression problems. The asymptotic properties such as the convergence rate and prediction error bound have been established. Simulations and a real data from ADHD-200 fMRI data are investigated to show the superiority of our proposed method.

math.ST

Partial Functional Linear Quantile Regression for Neuroimaging Data Analysis

We propose a prediction procedure for the functional linear quantile regression model by using partial quantile covariance techniques and develop a simple partial quantile regression (SIMPQR) algorithm to efficiently extract partial quantile regression (PQR) basis for estimating functional coefficients. We further extend our partial quantile covariance techniques to functional composite quantile regression (CQR) defining partial composite quantile covariance. There are three major contributions. (1) We define partial quantile covariance between two scalar variables through linear quantile regression. We compute PQR basis by sequentially maximizing the partial quantile covariance between the response and projections of functional covariates. (2) In order to efficiently extract PQR basis, we develop a SIMPQR algorithm analogous to simple partial least squares (SIMPLS). (3) Under the homoscedasticity assumption, we extend our techniques to partial composite quantile covariance and use it to find the partial composite quantile regression (PCQR) basis. The SIMPQR algorithm is then modified to obtain the SIMPCQR algorithm. Two simulation studies show the superiority of our proposed methods. Two real data from ADHD-200 sample and ADNI are analyzed using our proposed methods.

stat.ME