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Fan Ma

Publications and source records attributed to Fan Ma.

At least 19 recordsLinked to original sources
arXiv2026

Backbone-Informed Adaptation after EEG Pretraining: A Capacity-Controlled Study

Electroencephalography (EEG) foundation models learn representations that combine information across channels and time. This structure motivates adapters that model the same relationships during downstream learning. However, it is not clear whether such a design outperforms other candidate adapters. Moreover, in order to arrive at a fair comparison between candidate adapters, we also need to consider their trainable parameters. Here, we ask whether a backbone-informed (native) adapter makes better use of a given capacity by comparing it against a token-wise multilayer perceptron control that transforms each feature vector independently. We approximately match their trainable parameter counts and keep the pretrained encoder fixed. Across two EEG foundation models and tasks covering emotion recognition, sleep staging, and EEG event classification, the native adapter shows no consistent advantage. For one backbone, differences between the designs are small relative to variation across runs. For the other, the token-wise control performs better on emotion recognition and EEG event classification. On sleep staging, the native adapter's advantage over the token-wise control is reduced when we also train the component that processes sequences of EEG segments. The relative performance of the two adapters depends on the backbone, task, and downstream training protocol. These findings motivate evaluating backbone-informed adapters against capacity-matched alternatives.

cs.LG↗
arXiv2026

Foundation Models to Unlock Real-World Evidence from Nationwide Medical Claims

Real-world data increasingly inform regulatory and clinical decisions. Administrative claims, among their major sources, continuously track care and its cost across providers throughout enrollment, yet remain largely unexplored for healthcare foundation models. Here we present ReClaim, a family of generative foundation models built on 43.8 billion claims records from more than 200 million enrollees in the MarketScan Research Databases. ReClaim learns diagnoses, procedures, medications and expenditure jointly through pre-training from scratch, then specializes for downstream prediction tasks through post-training, with a training cutoff at the end of 2022. In predicting more than 1,000 diseases, ReClaim achieved a mean ROC-AUC of 0.769, outperforming disease-specific gradient-boosted models (0.663) and a transformer-based baseline (0.694), and retained this advantage when generalizing to two independent cross-domain electronic health record datasets. ReClaim also outperformed gradient-boosted models in forecasting next-year expenditure and in identifying high-need, high-cost enrollees. ReClaim maintained its advantage in disease prediction and expenditure forecasting on post-cutoff data (2023-2024). Beyond prediction, ReClaim representations used as covariates resulted in improved effect estimates compared with algorithm-derived covariates, when benchmarked against results expected from randomized controlled trials. Together, these results establish nationwide insurance claims as a scalable substrate for healthcare foundation models supporting disease prediction, expenditure forecasting and confounding adjustment in real-world evidence studies. Code is available at https://github.com/BIDS-Xu-Lab/ReClaim.

cs.AI↗
arXiv2026

Dataset-Dependent Effects of Cross-Depth Aggregation and Soft-Routed Experts in EEG Foundation Model Fine-Tuning

EEG decoding tasks can rely on different temporal dynamics and cross-channel relationships. We test whether specialized modules improve a fully fine-tuned EEG foundation model by augmenting CBraMod with cross-depth Attention Residuals (AttnRes) and two soft-routed expert banks. Across matched three-seed experiments on FACED, ISRUC, SEED-V, and PhysioNet-MI, the complete model changes mean balanced accuracy relative to full fine-tuning by -0.12, +1.27, +0.77, and -1.27 points, respectively. AttnRes alone improves mean balanced accuracy on three datasets, whereas adding experts on top of AttnRes helps only FACED and SEED-V. These gains come with substantial overhead: AttnRes requires 2.11 to 2.88x runtime and 1.78 to 2.67x memory, while the complete model requires 2.41 to 3.04x runtime and 1.86 to 2.85x memory. Overall, the added modules produce dataset-dependent, sometimes opposing effects rather than consistent gains over full fine-tuning.

cs.LG↗
arXiv2026

Teaching agentic AI to generalize expert diagnostic reasoning in rare diseases

Rare disease diagnosis depends on expert reasoning that is scarce and difficult to transfer. Large language models rank the correct disease first in only 35.4% of benchmark cases and often rely on learned phenotype-disease associations rather than reusable diagnostic reasoning strategies. We developed liteOdyssey through Policy Iteration with Human Feedback, a process in which model failures and expert corrections are iteratively consolidated into a clinician-gated, natural-language policy executed by a language model. Across 1,243 public benchmark cases spanning 722 rare diseases, liteOdyssey ranked the correct disease first in 59.3% of cases versus 26.5% without the policy, with comparable gains in cases involving diseases excluded from policy development. The same policy transferred across model families and sizes without retraining. Adaptation of the policy to the Undiagnosed Diseases Network (UDN) improved diagnostic accuracy among 515 UDN patients, with gains confirmed by blinded physician adjudication. These results show that expert reasoning can be externalized into an inspectable and revisable natural-language policy that generalizes across rare diseases, transfers across model backbones, and adapts to a real-world patient cohort.

cs.AI↗
arXiv2026

Velocity-coupled Representation Refinement for Satellite Orbit Prediction

Satellite orbit prediction, which aims to forecast future orbital trajectories from historical observations, is important for collision warning and safe space operations. With advances in time-series forecasting, learning-based methods have emerged as a promising solution for satellite prediction. In orbital dynamics, a satellite state is typically described by position and velocity, where position characterizes trajectory geometry and velocity reflects its instantaneous direction and rate of change. However, most existing methods mainly focus on temporal dependencies within position sequences while rarely exploiting the intrinsic coupling between position and velocity, which is essential for modeling satellite motion. To this end, we propose OrbitNet, a velocity-aware representation learning method for accurate satellite orbit prediction. It lifts conventional position-sequence forecasting to a position-velocity coupled representation learning paradigm by exploiting relationships among satellite state variables. Specifically, we develop a velocity-coupled representation refinement strategy to enhance positional representations through cross-variable interactions between position and velocity. We further introduce orbital segment modeling, which partitions historical trajectories into temporal segments and performs segment-level temporal learning to capture local motion variations and long-range evolution patterns. Extensive experiments show that OrbitNet outperforms large time-series foundation models and representative general forecasting methods under both in-domain evaluation on Starlink and zero-shot evaluation across six unseen satellite constellations. We expect this work to encourage further exploration of satellite-aware representation learning for trajectory time-series forecasting.

cs.CV↗
arXiv2026

PhyEdit: Towards Real-World Object Manipulation via Physically-Grounded Image Editing

Achieving physically accurate object manipulation in image editing is essential for its potential applications in interactive world models. However, existing visual generative models often fail at precise spatial manipulation, resulting in incorrect scaling and positioning of objects. This limitation primarily stems from the lack of explicit mechanisms to incorporate 3D geometry and perspective projection. To achieve accurate manipulation, we develop PhyEdit, an image editing framework that leverages explicit geometric simulation as contextual 3D-aware visual guidance. By combining this plug-and-play 3D prior with joint 2D--3D supervision, our method effectively improves physical accuracy and manipulation consistency. To support this method and evaluate performance, we present a real-world dataset, RealManip-40K, for 3D-aware object manipulation featuring paired images and depth annotations. We also propose ManipEval, a benchmark with multi-dimensional metrics to evaluate 3D spatial control and geometric consistency. Extensive experiments show that our approach outperforms existing methods, including strong closed-source models, in both 3D geometric accuracy and manipulation consistency.

cs.CV↗
arXiv2026

A safety-oriented hypothetico-deductive framework for AI-assisted differential diagnosis

Diagnostic error is a major threat to patient safety, yet current large language model (LLM) systems often treat diagnosis as a one-shot prediction task, lacking safeguards against missed high-risk alternatives or rigorous verification of their reasoning. Here, we present AegisDx, a safety-oriented framework for hypothetico-deductive clinical reasoning. AegisDx coordinates specialized LLM components through role-specific contracts, structured intermediate outputs, evidence-retrieval interfaces, and verification gates to generate broad differential diagnoses, enforce explicit screening for dangerous "must-not-miss" conditions, verify reasoning against grounded medical evidence, and structure actionable next steps. We evaluated AegisDx across three layers. On literature-derived case reports from NEJM and JAMA, with GPT-oss-120B as the shared backbone, Top-3 diagnostic accuracy was 59.9% versus 52.1% for the standalone LLM on JAMA cases and 62.7% versus 51.4% on NEJM cases. On cases from Annals of Emergency Medicine, Top-3 accuracy was 85.7% versus 68.6%; against physician-consensus must-not-miss diagnosis sets, AegisDx captured at least one such condition among its top three diagnoses in 78.0% of cases versus 52.0%. In a blinded physician evaluation of 43 real-world emergency department notes from the Yale New Haven Health System compared against GPT-5, AegisDx improved the physician-rated composite safety score from 4.31 to 4.55 on a 5-point scale (adjusted p = 2.1x10^-4), with qualitative gains in must-not-miss identification and reasoning safety. Our findings suggest that engineering diagnostic AI as a safety-oriented reasoning framework, rather than optimizing raw predictive accuracy alone, can provide a safer, more transparent, and clinically meaningful layer of bedside decision support for acute care workflows.

cs.AI↗
arXiv2026

TRACE: Temporal Routing with Autoregressive Cross-channel Experts for EEG Representation Learning

Learning transferable representations for electroencephalography (EEG) remains challenging because EEG signals are inherently multi-channel and non-stationary. Channels observed at the same time provide coupled measurements of neural activity, while the relevant temporal dynamics vary across contexts. This structure is poorly matched by architectures that apply uniform computation across time or route each channel patch independently. To this end, we propose TRACE, an autoregressive EEG pre-training framework that predicts future EEG patches from causal context while performing temporally adaptive and cross-channel coherent computation. At each temporal step, TRACE derives an expert routing decision from the causal cross-channel history and applies it jointly to all channels at that step. This preserves instantaneous cross-channel coherence while allowing different temporal regimes to activate different computation. Since routing is defined over the available channel set and causal temporal context, TRACE is compatible with heterogeneous pre-training across corpora with different channel counts, montages, sequence lengths, and recording domains. Across eight downstream EEG benchmarks, TRACE is evaluated in both settings: when downstream domains are seen only as unlabeled pre-training data and when downstream datasets are completely unseen during pre-training. It obtains the best results on several benchmarks while remaining competitive on motor imagery and clinical event classification tasks, with ablations supporting the importance of cross-channel temporal routing.

cs.LG↗
arXiv2026

FoleyDirector: Fine-Grained Temporal Steering for Video-to-Audio Generation via Structured Scripts

Recent Video-to-Audio (V2A) methods have achieved remarkable progress, enabling the synthesis of realistic, high-quality audio. However, they struggle with fine-grained temporal control in multi-event scenarios or when visual cues are insufficient, such as small regions, off-screen sounds, or occluded or partially visible objects. In this paper, we propose FoleyDirector, a framework that, for the first time, enables precise temporal guidance in DiT-based V2A generation while preserving the base model's audio quality and allowing seamless switching between V2A generation and temporally controlled synthesis. FoleyDirector introduces Structured Temporal Scripts (STS), a set of captions corresponding to short temporal segments, to provide richer temporal information. These features are integrated via the Script-Guided Temporal Fusion Module, which employs Temporal Script Attention to fuse STS features coherently. To handle complex multi-event scenarios, we further propose Bi-Frame Sound Synthesis, enabling parallel in-frame and out-of-frame audio generation and improving controllability. To support training and evaluation, we construct the DirectorSound dataset and introduce VGGSoundDirector and DirectorBench. Experiments demonstrate that FoleyDirector substantially enhances temporal controllability while maintaining high audio fidelity, empowering users to act as Foley directors and advancing V2A toward more expressive and controllable generation.

cs.SD↗
arXiv2026

LogiStory: A Logic-Aware Framework for Multi-Image Story Visualization

Generating coherent and communicative visual sequences, such as image sequences and videos, remains a significant challenge for current multimodal systems. Despite advances in visual quality and the integration of world knowledge, existing models still struggle to maintain logical flow, often resulting in disjointed actions, fragmented narratives, and unclear storylines. We attribute these issues to the lack of attention to visual logic, a critical yet underexplored dimension of visual sequence generation that we define as the perceptual and causal coherence among characters, actions, and scenes over time. To bridge this gap, we propose a logic-aware multi-image story visualization framework, LogiStory. The framework is built around the central innovation of explicitly modeling visual logic in story visualization. To realize this idea, we design a multi-agent system that grounds roles, extracts causal chains, and verifies story-level consistency, transforming narrative coherence from an implicit byproduct of image generation into an explicit modeling objective. This design effectively bridges structured story planning with visual generation, enhancing both narrative clarity and visual quality in story visualization. Furthermore, to evaluate the generation capacity, we construct LogicTale, a benchmark comprising richly annotated stories, emphasizing causal reasoning, and visual logic interpretability. We establish comprehensive automatic and human evaluation protocols designed to measure both visual logic and perceptual quality. Experiments demonstrate that our approach significantly improves the narrative logic of generated visual stories. This work provides a foundational step towards modeling and enforcing visual logic in general image sequence and video generation tasks.

cs.CV↗
arXiv2026

Echoes of ownership: Adversarial-guided dual injection for copyright protection in MLLMs

With the rapid deployment of multimodal large language models (MLLMs), disputes regarding model ownership have become increasingly frequent, raising significant concerns about intellectual property protection. In this paper, we propose a framework for generating copyright triggers for MLLMs, enabling model publishers to embed verifiable ownership information into the model. The goal is to construct trigger images that elicit ownership-related textual responses exclusively in fine-tuned derivatives, while remaining inert in other non-derivative models. Our method constructs a tracking trigger image by treating the image as a learnable tensor, performing adversarial optimization with dual-injection of ownership-relevant semantic information. The first injection is achieved by enforcing textual consistency between the output of an auxiliary MLLM and a predefined ownership-relevant target text; the consistency loss is backpropagated to inject this ownership-related information into the image. The second injection is performed at the semantic-level by minimizing the distance between the CLIP features of the image and those of the target text. Furthermore, we introduce an additional adversarial training stage involving the auxiliary model. It is specifically trained to resist generating ownership-relevant target text, thereby enhancing robustness in heavily fine-tuned derivative models. Extensive experiments demonstrate the effectiveness of our dual-injection approach in tracking model lineage under various fine-tuning and domain-shift scenarios. Code is at https://github.com/kunzhan/AGDI

cs.CV↗
arXiv2026

ContextGen: Contextual Layout Anchoring for Identity-Consistent Multi-Instance Generation

Multi-instance image generation (MIG) remains a significant challenge for modern diffusion models due to key limitations in achieving precise control over object layout and preserving the identity of multiple distinct subjects. To address these limitations, we introduce ContextGen, a novel Diffusion Transformer framework for multi-instance generation that is guided by both layout and reference images. Our approach integrates two key technical contributions: a Contextual Layout Anchoring (CLA) mechanism that incorporates the composite layout image into the generation context to robustly anchor the objects in their desired positions, and Identity Consistency Attention (ICA), an innovative attention mechanism that leverages contextual reference images to ensure the identity consistency of multiple instances. To address the absence of a large-scale, high-quality dataset for this task, we introduce IMIG-100K, the first dataset to provide detailed layout and identity annotations specifically designed for Multi-Instance Generation. Extensive experiments demonstrate that ContextGen sets a new state-of-the-art, outperforming existing methods especially in layout control and identity fidelity.

cs.CV↗
arXiv2026

EHRNavigator: A Multi-Agent System for Patient-Level Clinical Question Answering over Heterogeneous Electronic Health Records

Clinical decision-making increasingly relies on timely and context-aware access to patient information within Electronic Health Records (EHRs), yet most existing natural language question-answering (QA) systems are evaluated solely on benchmark datasets, limiting their practical relevance. To overcome this limitation, we introduce EHRNavigator, a multi-agent framework that harnesses AI agents to perform patient-level question answering across heterogeneous and multimodal EHR data. We assessed its performance using both public benchmark and institutional datasets under realistic hospital conditions characterized by diverse schemas, temporal reasoning demands, and multimodal evidence integration. Through quantitative evaluation and clinician-validated chart review, EHRNavigator demonstrated strong generalization, achieving 86% accuracy on real-world cases while maintaining clinically acceptable response times. Overall, these findings confirm that EHRNavigator effectively bridges the gap between benchmark evaluation and clinical deployment, offering a robust, adaptive, and efficient solution for real-world EHR question answering.

cs.CL↗
arXiv2025

AnchorFlow: Training-Free 3D Editing via Latent Anchor-Aligned Flows

Training-free 3D editing aims to modify 3D shapes based on human instructions without model finetuning. It plays a crucial role in 3D content creation. However, existing approaches often struggle to produce strong or geometrically stable edits, largely due to inconsistent latent anchors introduced by timestep-dependent noise during diffusion sampling. To address these limitations, we introduce AnchorFlow, which is built upon the principle of latent anchor consistency. Specifically, AnchorFlow establishes a global latent anchor shared between the source and target trajectories, and enforces coherence using a relaxed anchor-alignment loss together with an anchor-aligned update rule. This design ensures that transformations remain stable and semantically faithful throughout the editing process. By stabilizing the latent reference space, AnchorFlow enables more pronounced semantic modifications. Moreover, AnchorFlow is mask-free. Without mask supervision, it effectively preserves geometric fidelity. Experiments on the Eval3DEdit benchmark show that AnchorFlow consistently delivers semantically aligned and structurally robust edits across diverse editing types. Code is at https://github.com/ZhenglinZhou/AnchorFlow.

cs.CV↗
arXiv2025

ITS3D: Inference-Time Scaling for Text-Guided 3D Diffusion Models

We explore inference-time scaling in text-guided 3D diffusion models to enhance generative quality without additional training. To this end, we introduce ITS3D, a framework that formulates the task as an optimization problem to identify the most effective Gaussian noise input. The framework is driven by a verifier-guided search algorithm, where the search algorithm iteratively refines noise candidates based on verifier feedback. To address the inherent challenges of 3D generation, we introduce three techniques for improved stability, efficiency, and exploration capability. 1) Gaussian normalization is applied to stabilize the search process. It corrects distribution shifts when noise candidates deviate from a standard Gaussian distribution during iterative updates. 2) The high-dimensional nature of the 3D search space increases computational complexity. To mitigate this, a singular value decomposition-based compression technique is employed to reduce dimensionality while preserving effective search directions. 3) To further prevent convergence to suboptimal local minima, a singular space reset mechanism dynamically updates the search space based on diversity measures. Extensive experiments demonstrate that ITS3D enhances text-to-3D generation quality, which shows the potential of computationally efficient search methods in generative processes. The source code is available at https://github.com/ZhenglinZhou/ITS3D.

cs.CV↗
arXiv2025

InfiniDreamer: Arbitrarily Long Human Motion Generation via Segment Score Distillation

We present InfiniDreamer, a novel framework for arbitrarily long human motion generation. InfiniDreamer addresses the limitations of current motion generation methods, which are typically restricted to short sequences due to the lack of long motion training data. To achieve this, we first generate sub-motions corresponding to each textual description and then assemble them into a coarse, extended sequence using randomly initialized transition segments. We then introduce an optimization-based method called Segment Score Distillation (SSD) to refine the entire long motion sequence. SSD is designed to utilize an existing motion prior, which is trained only on short clips, in a training-free manner. Specifically, SSD iteratively refines overlapping short segments sampled from the coarsely extended long motion sequence, progressively aligning them with the pre-trained motion diffusion prior. This process ensures local coherence within each segment, while the refined transitions between segments maintain global consistency across the entire sequence. Extensive qualitative and quantitative experiments validate the superiority of our framework, showcasing its ability to generate coherent, contextually aware motion sequences of arbitrary length.

cs.CV↗
arXiv2025

Dynamic Experts Search: Enhancing Reasoning in Mixture-of-Experts LLMs at Test Time

Test-Time Scaling (TTS) enhances the reasoning ability of large language models (LLMs) by allocating additional computation during inference. However, existing approaches primarily rely on output-level sampling while overlooking the role of model architecture. In mainstream Mixture-of-Experts (MoE) LLMs, we observe that varying the number of activated experts yields complementary solution sets with stable accuracy, revealing a new and underexplored source of diversity. Motivated by this observation, we propose Dynamic Experts Search (DES), a TTS strategy that elevates expert activation into a controllable dimension of the search space. DES integrates two key components: (1) Dynamic MoE, which enables direct control of expert counts during inference to generate diverse reasoning trajectories without additional cost; and (2) Expert Configuration Inheritance, which preserves consistent expert counts within a reasoning path while varying them across runs, thereby balancing stability and diversity throughout the search. Extensive experiments across MoE architectures, verifiers and reasoning benchmarks (i.e., math, code and knowledge) demonstrate that DES reliably outperforms TTS baselines, enhancing accuracy and stability without additional cost. These results highlight DES as a practical and scalable form of architecture-aware TTS, illustrating how structural flexibility in modern LLMs can advance reasoning.

cs.AI↗
arXiv2025

Adversarial-Guided Diffusion for Multimodal LLM Attacks

This paper addresses the challenge of generating adversarial image using a diffusion model to deceive multimodal large language models (MLLMs) into generating the targeted responses, while avoiding significant distortion of the clean image. To address the above challenges, we propose an adversarial-guided diffusion (AGD) approach for adversarial attack MLLMs. We introduce adversarial-guided noise to ensure attack efficacy. A key observation in our design is that, unlike most traditional adversarial attacks which embed high-frequency perturbations directly into the clean image, AGD injects target semantics into the noise component of the reverse diffusion. Since the added noise in a diffusion model spans the entire frequency spectrum, the adversarial signal embedded within it also inherits this full-spectrum property. Importantly, during reverse diffusion, the adversarial image is formed as a linear combination of the clean image and the noise. Thus, when applying defenses such as a simple low-pass filtering, which act independently on each component, the adversarial image within the noise component is less likely to be suppressed, as it is not confined to the high-frequency band. This makes AGD inherently robust to variety defenses. Extensive experiments demonstrate that our AGD outperforms state-of-the-art methods in attack performance as well as in model robustness to some defenses.

cs.CV↗