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Hans A. Kestler

Publications and source records attributed to Hans A. Kestler.

3 recordsLinked to original sources

Few-Shot Learning for Personalised Automated Pain Assessment

Pain perception varies substantially across individuals, making it difficult for population-based classifiers to generalise across all subjects in a dataset. One way to account for subject variability is to train personalised classifiers. In this work, we evaluate Few-Shot Learning, a sub-area of Meta-Learning, as an approach to personalisation in automated pain assessment. We re-interpret the shift from population-level to subject-level evaluation as a task-domain shift, where the observed classes remain fixed but the target subject changes. We evaluate our method on the BioVid Pain Database, the SenseEmotion Database, and the PainMonit Experimental Dataset (PMED), reaching 85.75% and 35.49% accuracy on BioVid and 82.37% and 41.88% on SenseEmotion in the binary and multi-class settings under a Leave-One-Subject-Out CV protocol respectively, and 90.47% on PMED, for which only a binary benchmark exists. Using samples to implement k-shot conditioning, the accuracies can be improved to 86.25%, 40.06%, 83.43%, 44.08%, and 91.25%, respectively. To further evaluate the effects and robustness of our method, we provide additional ablation experiments and investigate the personalisation effects. Our results suggest that support-conditioned few-shot adaptation can improve average performance under inter-subject variability.

cs.LG↗

A Novel Quantum Algorithm for Efficient Attractor Search in Gene Regulatory Networks

The description of gene interactions that constantly occur in the cellular environment is an extremely challenging task due to an immense number of degrees of freedom and incomplete knowledge about microscopic details. Hence, a coarse-grained and rather powerful modeling of such dynamics is provided by Boolean Networks (BNs). BNs are dynamical systems composed of Boolean agents and a record of their possible interactions over time. Stable states in these systems are called attractors which are closely related to the cellular expression of biological phenotypes. Identifying the full set of attractors is, therefore, of substantial biological interest. However, for conventional high-performance computing, this problem is plagued by an exponential growth of the dynamic state space. Here, we demonstrate a novel quantum search algorithm inspired by Grover's algorithm to be implemented on quantum computing platforms. The algorithm performs an iterative suppression of states belonging to basins of previously discovered attractors from a uniform superposition, thus increasing the amplitudes of states in basins of yet unknown attractors. This approach guarantees that a new attractor state is measured with each iteration of the algorithm, an optimization not currently achieved by any other algorithm in the literature. Tests of its resistance to noise have also shown promising performance on devices from the current Noise Intermediate Scale Quantum Computing (NISQ) era.

quant-ph↗

Corona Health -- A Study- and Sensor-based Mobile App Platform Exploring Aspects of the COVID-19 Pandemic

Physical and mental well-being during the COVID-19 pandemic is typically assessed via surveys, which might make it difficult to conduct longitudinal studies and might lead to data suffering from recall bias. Ecological momentary assessment (EMA) driven smartphone apps can help alleviate such issues, allowing for in situ recordings. Implementing such an app is not trivial, necessitates strict regulatory and legal requirements, and requires short development cycles to appropriately react to abrupt changes in the pandemic. Based on an existing app framework, we developed Corona Health, an app that serves as a platform for deploying questionnaire-based studies in combination with recordings of mobile sensors. In this paper, we present the technical details of Corona Health and provide first insights into the collected data. Through collaborative efforts from experts from public health, medicine, psychology, and computer science, we released Corona Health publicly on Google Play and the Apple App Store (in July, 2020) in 8 languages and attracted 7,290 installations so far. Currently, five studies related to physical and mental well-being are deployed and 17,241 questionnaires have been filled out. Corona Health proves to be a viable tool for conducting research related to the COVID-19 pandemic and can serve as a blueprint for future EMA-based studies. The data we collected will substantially improve our knowledge on mental and physical health states, traits and trajectories as well as its risk and protective factors over the course of the COVID-19 pandemic and its diverse prevention measures.

cs.CY↗