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Jason Lee

Publications and source records attributed to Jason Lee.

At least 19 recordsLinked to original sources

BixBench3: Benchmarking AI agents on research-study-scale computational biology tasks

Artificial intelligence (AI) promises to accelerate biological research by automating computational analyses. Yet the ability of AI agents to carry out computational biology at the scale of complete research studies has not been systematically evaluated. Here we introduce BixBench3, a benchmark that measures the capacity of AI agents to process raw biological data through to scientific results. We designed BixBench3 tasks to mirror the delegation of work from a scientist to an agent: the scientist chooses the research question and high-level methods, then delegates implementation of all analyses to the agent. In each task, an agent receives a research objective, methodological guidance, and raw data derived from a published scientific study, and must execute a sequence of analyses to achieve the research objective. The data artifacts resulting from these analyses - such as peak call matrices or differential expression tables - are programmatically graded against the corresponding artifacts generated and reported in the original study. Across 20 BixBench3 tasks encompassing the generation of 138 unique artifacts, we find that 13 frontier models achieve scores ranging from 0.00 for Gemini 3.1 Flash Lite to 0.48 for GPT 5.6 Sol. Agents perform worse on tasks with larger raw datasets (0.36 on tasks with <100 GB versus 0.10 on tasks with >100 GB) and on analyses requiring more sequential steps (0.36 at 1-2 steps vs 0.24 at 3+). On average, agents use 6.8 hours, 102 million tokens, and $43 to complete each task, with the longest attempts consuming 24 hours, 1.07 billion tokens, and $525. Notably, the highest-scoring agents used fewer tokens and were cheaper than less performant options. These results reveal that LLMs vary substantially in their ability to (1) execute multiple sequential analysis steps coherently, (2) manage large quantities of raw data, and (3) work across scientific domains.

cs.AI

A broadband, individually addressing two- and three-dimensional photonic integrated circuit for trapped-ion qubit control

Trapped ions provide a high-fidelity platform for quantum information processing, yet delivery of multiple, distinct wavelengths across large networks of interaction zones remains a bottleneck. Conventional free-space light delivery lacks scalability, while on-chip grating couplers suffer from narrow operational bandwidth that increases circuit footprint and optical interfacing complexity. Here we show a broadband photonic integrated circuit capable of addressing individual ions. The circuit combines a planar waveguide lens with a micromirror fabricated using two-photon polymerization at wafer scale. This implementation can address three individual ions from $\lambda$ = 405 - 880 nm with -27 dB average intensity crosstalk at $5\,\mu\mathrm{m}$ pitch. We trap $^{40}\mathrm{Ca}^{+}$ and $^{138}\mathrm{Ba}^{+}$ ions above such devices, characterize optical crosstalk with barium ions, and demonstrate individual repumping of calcium ions. This monolithic photonic architecture brings broadband addressing in an on-chip modality to trapped-ion technology. More generally, integrating additive manufacturing into quantum devices is poised to unlock expanded design space for implementing novel quantum architectures.

quant-ph

TAM: Torque Adaptation Module for Robust Motion Transfer in Manipulation

A policy tuned for one robot often behaves differently on another, whether due to the sim-to-real gap, unknown payloads, or the differing dynamics of two instances of the same robot. In contact-rich, dynamic manipulation, even small motion discrepancies can result in failure to track reference motion, since they disrupt the timing and modes of contact. Common remedies, such as domain randomization or system identification, either produce overly conservative task policies or require data that must be recollected for each robot or payload. We introduce the Torque Adaptation Module (TAM), a learned module that adapts the torque commands sent to the robot to match the behavior of an ideal robot. TAM operates between the low-level controller that tracks the policy's actions and the robot's torque interface. It includes a history encoder that embeds proprioceptive history into a latent state and a torque adaptor that computes residual torque corrections. Because TAM depends only on proprioceptive history and not on policy observations, or the action space, the same TAM weights can be reused to adapt policies with different action spaces (joint targets, end-effector targets, or direct torques). The policies themselves do not need to be trained with domain randomization of robot parameters. Instead, we offload the need for domain randomization to TAM by training it entirely in randomized simulation, using multi-robot pretraining followed by a robot-specific fine-tuning step that still requires no real-robot data. We evaluate TAM zero-shot on a real Franka Panda robot across dynamic manipulation tasks that include a vision-based box pushing policy (from RL), a flip policy (from BC), and an MPC ball-on-plate balancing. Our experiments show that TAM improves zero-shot real-robot execution compared to online system identification and RMA baselines and enables robust dynamic manipulation performance.

cs.RO

20/20 Vision Language Models: A Prescription for Better VLMs through Data Curation Alone

Data curation has shifted the quality-compute frontier for language-model and contrastive image-text pretraining, but its role for vision-language models (VLMs) is far less established. We ask how far data curation alone can take VLM performance, holding architecture, training recipe, and compute fixed and varying only the training data. Our pipeline, applied to the MAmmoTH-VL single-image subset, lifts performance by +11.7pp on average across 20 public VLM benchmarks (spanning grounding, VQA, OCR/documents, captioning, spatial/3D, counting, charts, math, brand-ID, and multi-image reasoning) and by +11.3pp on average across all nine capability axes of DatBench, our high-fidelity VLM eval suite. At 2B, our curated model surpasses InternVL3.5-2B by 9.9pp at ~17x less training compute and closes the gap to Qwen3-VL-2B to within 1.8pp at ~87x less compute, from pretraining alone. Beyond accuracy, curation delivers four further properties: (1) Reliability: per-capability std across training seeds drops by ~67% and the lift survives a 4k-to-16k context-length sweep; (2) OOD generalization: the 9-eval OOD average rises by +7.2pp, and multi-image BLINK rises by +3.09pp despite single-image-only training, with Visual Correspondence gaining +11.8pp; (3) Behavioral gains beyond benchmarks: across ~1,100 open-ended queries the curated 2B is more honest and more specific than the matched-compute baseline, and more concise and less refusal-prone than a frontier 2B reference; (4) Pareto-dominance on inference cost: at every scale (1B, 2B, 4B) the curated model raises accuracy while lowering response FLOPs vs. the matched-compute baseline, and the curated 4B matches near-frontier accuracy at 3.3x lower response FLOPs than Qwen3-VL-4B. Data curation is a high-leverage tool for building better VLMs, reaching near-frontier accuracy at up to ~150x less training compute.

cs.LG

\"UberWeb: Insights from Multilingual Curation for a 20-Trillion-Token Dataset

Multilinguality is a core capability for modern foundation models, yet training high-quality multilingual models remains challenging due to uneven data availability across languages. A further challenge is the performance interference that can arise from joint multilingual training, commonly referred to as the "curse of multilinguality". We study multilingual data curation across thirteen languages and find that many reported regressions are not inherent to multilingual scaling but instead stem from correctable deficiencies in data quality and composition rather than fundamental capacity limits. In controlled bilingual experiments, improving data quality for any single language benefits others: curating English improves non-English performance in 12 of 13 languages, while curating non-English yields reciprocal improvements in English. Bespoke per-language curation produces substantially larger within-language improvements. Extending these findings to large-scale general-purpose training mixtures, we show that curated multilingual allocations comprising under 8% of total tokens remain remarkably effective. We operationalize this approach within an effort that produced a 20T-token pretraining corpus derived entirely from public sources. Models with 3B and 8B parameters trained on a 1T-token random subset achieve competitive multilingual accuracy with 4-10x fewer training FLOPs than strong public baselines, establishing a new Pareto frontier in multilingual performance versus compute. Moreover, these benefits extend to frontier model scale: the 20T-token corpus served as part of the pretraining dataset for Trinity Large (400B/A13B), which exhibits strong multilingual performance relative to its training FLOPs. These results show that targeted, per-language data curation mitigates multilingual interference and enables compute-efficient multilingual scaling.

cs.LG

DatBench: Discriminative, Faithful, and Efficient VLM Evaluations

Empirical evaluation serves as the primary compass guiding research progress in foundation models. Despite a large body of work focused on training frontier vision-language models (VLMs), approaches to their evaluation remain nascent. To guide their maturation, we propose three desiderata that evaluations should satisfy: (1) faithfulness to the modality and application, (2) discriminability between models of varying quality, and (3) efficiency in compute. Through this lens, we identify critical failure modes that violate faithfulness and discriminability, misrepresenting model capabilities: (i) multiple-choice formats reward guessing, poorly reflect downstream use cases, and saturate early as models improve; (ii) blindly solvable questions, which can be answered without images, constitute up to 70% of some evaluations; and (iii) mislabeled or ambiguous samples compromise up to 42% of examples in certain datasets. Regarding efficiency, the computational burden of evaluating frontier models has become prohibitive: by some accounts, nearly 20% of development compute is devoted to evaluation alone. Rather than discarding existing benchmarks, we curate them via transformation and filtering to maximize fidelity and discriminability. We find that converting multiple-choice questions to generative tasks reveals sharp capability drops of up to 35%. In addition, filtering blindly solvable and mislabeled samples improves discriminative power while simultaneously reducing computational cost. We release DatBench-Full, a cleaned evaluation suite of 33 datasets spanning nine VLM capabilities, and DatBench, a discriminative subset that achieves 13x average speedup (up to 50x) while closely matching the discriminative power of the original datasets. Our work outlines a path toward evaluation practices that are both rigorous and sustainable as VLMs continue to scale.

cs.LG

Luxical: High-Speed Lexical-Dense Text Embeddings

Frontier language model quality increasingly hinges on our ability to organize web-scale text corpora for training. Today's dominant tools trade off speed and flexibility: lexical classifiers (e.g., FastText) are fast but limited to producing classification output scores, while the vector-valued outputs of transformer text embedding models flexibly support numerous workflows (e.g., clustering, classification, and retrieval) but are computationally expensive to produce. We introduce Luxical, a library for high-speed "lexical-dense" text embeddings that aims to recover the best properties of both approaches for web-scale text organization. Luxical combines sparse TF--IDF features, a small ReLU network, and a knowledge distillation training regimen to approximate large transformer embedding models at a fraction of their operational cost. In this technical report, we describe the Luxical architecture and training objective and evaluate a concrete Luxical model in two disparate applications: a targeted webcrawl document retrieval test and an end-to-end language model data curation task grounded in text classification. In these tasks we demonstrate speedups ranging from 3x to 100x over varying-sized neural baselines, and comparable to FastText model inference during the data curation task. On these evaluations, the tested Luxical model illustrates favorable compute/quality trade-offs for large-scale text organization, matching the quality of neural baselines. Luxical is available as open-source software at https://github.com/datologyai/luxical.

cs.CL

MolmoAct: Action Reasoning Models that can Reason in Space

Reasoning is central to purposeful action, yet most robotic foundation models map perception and instructions directly to control, which limits adaptability, generalization, and semantic grounding. We introduce Action Reasoning Models (ARMs), a class of robotic foundation models that integrate perception, planning, and control through a structured three-stage pipeline. Our model, MolmoAct, encodes observations and instructions into depth-aware perception tokens, generates mid-level spatial plans as editable trajectory traces, and predicts precise low-level actions, enabling explainable and steerable behavior. MolmoAct-7B-D achieves strong performance across simulation and real-world settings: 70.5% zero-shot accuracy on SimplerEnv Visual Matching tasks, surpassing closed-source Pi-0 and GR00T N1.5; 86.6% average success on LIBERO, including an additional 6.3% gain over ThinkAct on long-horizon tasks; and in real-world fine-tuning, an additional 10% (single-arm) and an additional 22.7% (bimanual) task progression over Pi-0-FAST. It also outperforms baselines by an additional 23.3% on out-of-distribution generalization and achieves top human-preference scores for open-ended instruction following and trajectory steering. Furthermore, we release, for the first time, the MolmoAct Dataset -- a mid-training robot dataset comprising over 10,000 high quality robot trajectories across diverse scenarios and tasks. Training with this dataset yields an average 5.5% improvement in general performance over the base model. We release all model weights, training code, our collected dataset, and our action reasoning dataset, establishing MolmoAct as both a state-of-the-art robotics foundation model and an open blueprint for building ARMs that transform perception into purposeful action through structured reasoning. Blogpost: https://allenai.org/blog/molmoact

cs.RO

Scalable contribution bounding to achieve privacy

In modern datasets, where single records can have multiple owners, enforcing user-level differential privacy requires capping each user's total contribution. This "contribution bounding" becomes a significant combinatorial challenge. Existing sequential algorithms for this task are computationally intensive and do not scale to the massive datasets prevalent today. To address this scalability bottleneck, we propose a novel and efficient distributed algorithm. Our approach models the complex ownership structure as a hypergraph, where users are vertices and records are hyperedges. The algorithm proceeds in rounds, allowing users to propose records in parallel. A record is added to the final dataset only if all its owners unanimously agree, thereby ensuring that no user's predefined contribution limit is violated. This method aims to maximize the size of the resulting dataset for high utility while providing a practical, scalable solution for implementing user-level privacy in large, real-world systems.

cs.DS

PointArena: Probing Multimodal Grounding Through Language-Guided Pointing

Pointing serves as a fundamental and intuitive mechanism for grounding language within visual contexts, with applications spanning robotics, assistive technologies, and interactive AI systems. While recent multimodal models have started to support pointing capabilities, existing benchmarks typically focus only on referential object localization tasks. We introduce PointArena, a comprehensive platform for evaluating multimodal pointing across diverse reasoning scenarios. PointArena comprises three components: (1) Point-Bench, a curated dataset containing approximately 1,000 pointing tasks across five reasoning categories; (2) Point-Battle, an interactive, web-based arena facilitating blind, pairwise model comparisons, which has already gathered over 4,500 anonymized votes; and (3) Point-Act, a real-world robotic manipulation system allowing users to directly evaluate multimodal model pointing capabilities in practical settings. We conducted extensive evaluations of both state-of-the-art open-source and proprietary multimodal models. Results indicate that Molmo-72B consistently outperforms other models, though proprietary models increasingly demonstrate comparable performance. Additionally, we find that supervised training specifically targeting pointing tasks significantly enhances model performance. Across our multi-stage evaluation pipeline, we also observe strong correlations, underscoring the critical role of precise pointing capabilities in enabling multimodal models to effectively bridge abstract reasoning with concrete, real-world actions. Project page: https://pointarena.github.io/

cs.CV

LZ Penalty: An information-theoretic repetition penalty for autoregressive language models

We introduce the LZ penalty, a penalty specialized for reducing degenerate repetitions in autoregressive language models without loss of capability. The penalty is based on the codelengths in the LZ77 universal lossless compression algorithm. Through the lens of the prediction-compression duality, decoding the LZ penalty has the interpretation of sampling from the residual distribution after removing the information that is highly compressible. We demonstrate the LZ penalty enables state-of-the-art open-source reasoning models to operate with greedy (temperature zero) decoding without loss of capability and without instances of degenerate repetition. Both the industry-standard frequency penalty and repetition penalty are ineffective, incurring degenerate repetition rates of up to 4%.

cs.LG

Response to recent comments on Phys. Rev. B 107, 245423 (2023) and Subsection S4.3 of the Supp. Info. for Nature 638, 651-655 (2025)

The topological gap protocol (TGP) is a statistical test designed to identify a topological phase with high confidence and without human bias. It is used to determine a promising parameter regime for operating topological qubits. The protocol's key metric is the probability of incorrectly identifying a trivial region as topological, referred to as the false discovery rate (FDR). Two recent manuscripts [arXiv:2502.19560, arXiv:2503.08944] engage with the topological gap protocol and its use in Phys. Rev. B 107, 245423 (2023) and Subsection S4.3 of the Supplementary Information for Nature 638, 651-655 (2025), although they do not explicitly dispute the main results of either one. We demonstrate that the objections in arXiv:2502.19560 and arXiv:2503.08944 are unfounded, and we uphold the conclusions of Phys. Rev. B 107, 245423 (2023) and Nature 638, 651-655 (2025). Specifically, we show that no flaws have been identified in our estimate of the false discovery rate (FDR). We provide a point-by-point rebuttal of the comments in arXiv:2502.19560 and arXiv:2503.08944.

cond-mat.mes-hall

Cross-Modal State-Space Graph Reasoning for Structured Summarization

The ability to extract compact, meaningful summaries from large-scale and multimodal data is critical for numerous applications, ranging from video analytics to medical reports. Prior methods in cross-modal summarization have often suffered from high computational overheads and limited interpretability. In this paper, we propose a \textit{Cross-Modal State-Space Graph Reasoning} (\textbf{CSS-GR}) framework that incorporates a state-space model with graph-based message passing, inspired by prior work on efficient state-space models. Unlike existing approaches relying on purely sequential models, our method constructs a graph that captures inter- and intra-modal relationships, allowing more holistic reasoning over both textual and visual streams. We demonstrate that our approach significantly improves summarization quality and interpretability while maintaining computational efficiency, as validated on standard multimodal summarization benchmarks. We also provide a thorough ablation study to highlight the contributions of each component.

cs.CL

Roadmap to fault tolerant quantum computation using topological qubit arrays

We describe a concrete device roadmap towards a fault-tolerant quantum computing architecture based on noise-resilient, topologically protected Majorana-based qubits. Our roadmap encompasses four generations of devices: a single-qubit device that enables a measurement-based qubit benchmarking protocol; a two-qubit device that uses measurement-based braiding to perform single-qubit Clifford operations; an eight-qubit device that can be used to show an improvement of a two-qubit operation when performed on logical qubits rather than directly on physical qubits; and a topological qubit array supporting lattice surgery demonstrations on two logical qubits. Devices that enable this path require a superconductor-semiconductor heterostructure that supports a topological phase, quantum dots and coupling between those quantum dots that can create the appropriate loops for interferometric measurements, and a microwave readout system that can perform fast, low-error single-shot measurements. We describe the key design components of these qubit devices, along with the associated protocols for demonstrations of single-qubit benchmarking, Clifford gate execution, quantum error detection, and quantum error correction, which differ greatly from those in more conventional qubits. Finally, we comment on implications and advantages of this architecture for utility-scale quantum computation.

quant-ph

Shifting Attention to You: Personalized Brain-Inspired AI Models

The integration of human and artificial intelligence offers a powerful avenue for advancing our understanding of information processing, as each system provides unique computational insights. However, despite the promise of human-AI integration, current AI models are largely trained on massive datasets, optimized for population-level performance, lacking mechanisms to align their computations with individual users' perceptual semantics and neural dynamics. Here we show that integrating human behavioral insights and millisecond scale neural data within a fine tuned CLIP based model not only captures generalized and individualized aspects of perception but also over doubles behavioral performance compared to the unmodified CLIP baseline. By embedding human inductive biases and mirroring dynamic neural processes during training, personalized neural fine tuning improves predictions of human similarity judgments and tracks the temporal evolution of individual neural responses. Our work establishes a novel, interpretable framework for designing adaptive AI systems, with broad implications for neuroscience, personalized medicine, and human-computer interaction.

q-bio.NC

Metastable Dynamics of Chain-of-Thought Reasoning: Provable Benefits of Search, RL and Distillation

A key paradigm to improve the reasoning capabilities of large language models (LLMs) is to allocate more inference-time compute to search against a verifier or reward model. This process can then be utilized to refine the pretrained model or distill its reasoning patterns into more efficient models. In this paper, we study inference-time compute by viewing chain-of-thought (CoT) generation as a metastable Markov process: easy reasoning steps (e.g., algebraic manipulations) form densely connected clusters, while hard reasoning steps (e.g., applying a relevant theorem) create sparse, low-probability edges between clusters, leading to phase transitions at longer timescales. Under this framework, we prove that implementing a search protocol that rewards sparse edges improves CoT by decreasing the expected number of steps to reach different clusters. In contrast, we establish a limit on reasoning capability when the model is restricted to local information of the pretrained graph. We also show that the information gained by search can be utilized to obtain a better reasoning model: (1) the pretrained model can be directly finetuned to favor sparse edges via policy gradient methods, and moreover (2) a compressed metastable representation of the reasoning dynamics can be distilled into a smaller, more efficient model.

cs.AI

Asynchronous Tool Usage for Real-Time Agents

While frontier large language models (LLMs) are capable tool-using agents, current AI systems still operate in a strict turn-based fashion, oblivious to passage of time. This synchronous design forces user queries and tool-use to occur sequentially, preventing the systems from multitasking and reducing interactivity. To address this limitation, we introduce asynchronous AI agents capable of parallel processing and real-time tool-use. Our key contribution is an event-driven finite-state machine architecture for agent execution and prompting, integrated with automatic speech recognition and text-to-speech. Drawing inspiration from the concepts originally developed for real-time operating systems, this work presents both a conceptual framework and practical tools for creating AI agents capable of fluid, multitasking interactions.

cs.AI

Constraints on compact objects from the Dark Energy Survey five-year supernova sample

Gravitational lensing magnification of Type Ia supernovae (SNe Ia) allows information to be obtained about the distribution of matter on small scales. In this paper, we derive limits on the fraction $\alpha$ of the total matter density in compact objects (which comprise stars, stellar remnants, small stellar groupings and primordial black holes) of mass $M > 0.03 M_{\odot}$ over cosmological distances. Using 1,532 SNe Ia from the Dark Energy Survey Year 5 sample (DES-SN5YR) combined with a Bayesian prior for the absolute magnitude $M$, we obtain $\alpha < 0.12$ at the 95\% confidence level after marginalisation over cosmological parameters, lensing due to large-scale structure, and intrinsic non-Gaussianity. Similar results are obtained using priors from the cosmic microwave background, baryon acoustic oscillations and galaxy weak lensing, indicating our results do not depend on the background cosmology. We argue our constraints are likely to be conservative (in the sense of the values we quote being higher than the truth), but discuss scenarios in which they could be weakened by systematics of the order of $\Delta \alpha \sim 0.04$

astro-ph.CO