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Jiazhen Pan

Publications and source records attributed to Jiazhen Pan.

3 recordsLinked to original sources

Agentic Large Language Models for Training-Free Neuro-Radiological Image Analysis

State-of-the-art large language models (LLMs) show high performance in general visual question answering. However, a fundamental limitation remains: current architectures lack the native 3D spatial reasoning required to directly analyze volumetric medical imaging, such as CT or MRI. Emerging agentic AI offers a new solution, eliminating the need for intrinsic 3D processing by enabling LLMs to orchestrate and leverage specialized external tools. Yet, the feasibility of such agentic frameworks in complex, multi-step radiological workflows remains underexplored. In this work, we present a training-free agentic pipeline for automated brain MRI analysis. Validating our methodology on several LLMs (GPT-5.4, Gemini 3.1 Pro, Claude Sonnet 4.6) with off-the-shelf domain-specific tools, our system autonomously executes complex end-to-end workflows, including preprocessing (skull stripping, registration), pathology segmentation (glioma, meningioma, metastases), and volumetric reasoning. We evaluate our framework across increasingly complex radiological tasks, from single-scan tumor and anatomy analysis to longitudinal response assessment requiring multi-timepoint comparisons. We analyze the impact of architectural design by comparing single-agent models against multi-agent "domain-expert" collaborations. To support rigorous evaluation of future agentic systems, we release a benchmark dataset of image-prompt-answer tuples derived from public data. Our results demonstrate that agentic AI can solve highly neuro-radiological image analysis tasks through tool use without the need for training or fine-tuning.

cs.CV

Are LLMs Ready to Assist Physicians? PhysAssistBench for Interactive Doctor-Patient-EHR Assistance

The most plausible near-term role of medical LLMs is to assist rather than replace physicians, yet current evaluations often test isolated capabilities: clinical knowledge, EHR system interaction, or patient communication. Physician assistance instead requires coordinating these capabilities within the same interaction, where physicians issue underspecified requests, patients describe symptoms ambiguously, and EHR systems demand precise tool use. We introduce PhysAssistBench, a benchmark for interactive doctor-patient-EHR assistance. Built from real MIMIC-IV cases, PhysAssistBench uses a scalable pipeline to construct agentic patients: interactive, record-grounded agents that turn static EHR records into multi-turn clinical scenarios while preserving clinical factuality. PhysAssistBench provides a curated bilingual evaluation set of 1,296 manually reviewed and physician-validated turns. Experiments with leading LLMs show that current models remain unreliable in this setting, which exposes a key bottleneck for clinical LLMs: reliable assistance requires coordination across knowledge, communication, and systems, not isolated gains in any of them.

cs.CL

AI Can Be Easily Persuaded in Clinical Decision Making

As AI becomes increasingly integrated into clinical practice, it is playing a growing role in medical decision making. Medicine, however, is a high stakes and evidence based field, where decisions can directly affect patients' lives. It is therefore important to understand whether AI can maintain objective judgment when others try to persuade it. In this paper, we study how easily AI can be persuaded through controlled experiments. We find that professional authority, national background, institutional affiliation, claimed past performance, multiple physicians, supported clinician views, and repeated pressure can all affect AI decisions. Surprisingly, the same persuasive input changes about 10% more cases when it comes from a senior clinician than from a medical student. Simply claiming a better performance history consistently makes the physician more persuasive. More strikingly, a plausible clinician view can persuade AI away from a correct decision even when it is fabricated to support an incorrect answer. This indicates that AI can be strongly influenced by convincing support without reliably determining whether this view from the clinician is correct. Together, these findings suggest that AI can be easily persuaded by what people say, who says it, and how the opinion is presented. Therefore, it is essential for AI to maintain sound judgment under persuasion, enabling its safe and reliable use in high stakes medical decision making.

cs.CL