arXiv subjects

Jie Xu

Publications and source records attributed to Jie Xu.

At least 145 records · Page 8Linked to original sources

arXiv2025

Global-Graph Guided and Local-Graph Weighted Contrastive Learning for Unified Clustering on Incomplete and Noise Multi-View Data

Recently, contrastive learning (CL) plays an important role in exploring complementary information for multi-view clustering (MVC) and has attracted increasing attention. Nevertheless, real-world multi-view data suffer from data incompleteness or noise, resulting in rare-paired samples or mis-paired samples which significantly challenges the effectiveness of CL-based MVC. That is, rare-paired issue prevents MVC from extracting sufficient multi-view complementary information, and mis-paired issue causes contrastive learning to optimize the model in the wrong direction. To address these issues, we propose a unified CL-based MVC framework for enhancing clustering effectiveness on incomplete and noise multi-view data. First, to overcome the rare-paired issue, we design a global-graph guided contrastive learning, where all view samples construct a global-view affinity graph to form new sample pairs for fully exploring complementary information. Second, to mitigate the mis-paired issue, we propose a local-graph weighted contrastive learning, which leverages local neighbors to generate pair-wise weights to adaptively strength or weaken the pair-wise contrastive learning. Our method is imputation-free and can be integrated into a unified global-local graph-guided contrastive learning framework. Extensive experiments on both incomplete and noise settings of multi-view data demonstrate that our method achieves superior performance compared with state-of-the-art approaches.

cs.LG↗

arXiv2025

Multi-Agent Intelligence for Multidisciplinary Decision-Making in Gastrointestinal Oncology

Multimodal clinical reasoning in the field of gastrointestinal (GI) oncology necessitates the integrated interpretation of endoscopic imagery, radiological data, and biochemical markers. Despite the evident potential exhibited by Multimodal Large Language Models (MLLMs), they frequently encounter challenges such as context dilution and hallucination when confronted with intricate, heterogeneous medical histories. In order to address these limitations, a hierarchical Multi-Agent Framework is proposed, which emulates the collaborative workflow of a human Multidisciplinary Team (MDT). The system attained a composite expert evaluation score of 4.60/5.00, thereby demonstrating a substantial improvement over the monolithic baseline. It is noteworthy that the agent-based architecture yielded the most substantial enhancements in reasoning logic and medical accuracy. The findings indicate that mimetic, agent-based collaboration provides a scalable, interpretable, and clinically robust paradigm for automated decision support in oncology.

cs.AI↗

arXiv2025

Native Intelligence Emerges from Large-Scale Clinical Practice: A Retinal Foundation Model with Deployment Efficiency

Current retinal foundation models remain constrained by curated research datasets that lack authentic clinical context, and require extensive task-specific optimization for each application, limiting their deployment efficiency in low-resource settings. Here, we show that these barriers can be overcome by building clinical native intelligence directly from real-world medical practice. Our key insight is that large-scale telemedicine programs, where expert centers provide remote consultations across distributed facilities, represent a natural reservoir for learning clinical image interpretation. We present ReVision, a retinal foundation model that learns from the natural alignment between 485,980 color fundus photographs and their corresponding diagnostic reports, accumulated through a decade-long telemedicine program spanning 162 medical institutions across China. Through extensive evaluation across 27 ophthalmic benchmarks, we demonstrate that ReVison enables deployment efficiency with minimal local resources. Without any task-specific training, ReVision achieves zero-shot disease detection with an average AUROC of 0.946 across 12 public benchmarks and 0.952 on 3 independent clinical cohorts. When minimal adaptation is feasible, ReVision matches extensively fine-tuned alternatives while requiring orders of magnitude fewer trainable parameters and labeled examples. The learned representations also transfer effectively to new clinical sites, imaging domains, imaging modalities, and systemic health prediction tasks. In a prospective reader study with 33 ophthalmologists, ReVision's zero-shot assistance improved diagnostic accuracy by 14.8% across all experience levels. These results demonstrate that clinical native intelligence can be directly extracted from clinical archives without any further annotation to build medical AI systems suited to various low-resource settings.

cs.CV↗

arXiv2025

Channel Knowledge Map Enabled Low-Altitude ISAC Networks: Joint Air Corridor Planning and Base Station Deployment

This letter addresses the joint air corridor planning and base station (BS) deployment problem for low-altitude integrated sensing and communication (ISAC) networks. In the considered system, unmanned aerial vehicles (UAVs) operate within a structured air corridor composed of connected cubic segments, and multiple BSs need to be selectively deployed at a set of candidate locations to ensure both sensing and communication coverage throughout the corridor. In particular, we leverage the channel knowledge map (CKM) to characterize wireless channels for candidate BS sites prior to deployment, thereby facilitating the offline planning. Under this setup, we minimize the system cost in terms of the weighted sum of the air corridor length and the number of deployed BSs, subject to the constraints on both sensing and communication performance across the corridor. To solve the formulated large-scale nonconvex integer programming problem, we develop a hierarchical coarse-to-fine grid decomposition algorithm. Simulation results demonstrate the benefit of the proposed joint design in reducing the overall deployment cost while ensuring the coverage of the low-altitude ISAC networks.

eess.SP↗

arXiv2025

EpiPlanAgent: Agentic Automated Epidemic Response Planning

Epidemic response planning is essential yet traditionally reliant on labor-intensive manual methods. This study aimed to design and evaluate EpiPlanAgent, an agent-based system using large language models (LLMs) to automate the generation and validation of digital emergency response plans. The multi-agent framework integrated task decomposition, knowledge grounding, and simulation modules. Public health professionals tested the system using real-world outbreak scenarios in a controlled evaluation. Results demonstrated that EpiPlanAgent significantly improved the completeness and guideline alignment of plans while drastically reducing development time compared to manual workflows. Expert evaluation confirmed high consistency between AI-generated and human-authored content. User feedback indicated strong perceived utility. In conclusion, EpiPlanAgent provides an effective, scalable solution for intelligent epidemic response planning, demonstrating the potential of agentic AI to transform public health preparedness.

cs.AI↗

arXiv2025

Numerical approximations to invariant measures of hybrid stochastic differential equations with superlinear coefficients via the backward Euler-Maruyama method

For stochastic differential equations (SDEs) with Markovian switching, whose drift and diffusion coefficients are allowed to contain superlinear terms, the backward Euler-Maruyama (BEM) method is proposed to approximate the invariant measure. The existence and uniqueness of the invariant measure of the numerical solution generated by the BEM method is proved. Then the convergence of the numerical invariant measure to its underlying counterpart is shown. Those results obtained in this work release the requirement of the global Lipschitz condition on the diffusion coefficient in [X. Li et al. SIAM J. Numer. Anal. 56(3)(2018), pp. 1435-1455] and can also be regarded as a non-trivial extension of [W. Liu et al. Appl. Numer. Math. 184(2023), pp. 137-150] to the case of hybrid SDEs.

math.NA↗

arXiv2025

Closing the Generalization Gap in Parameter-efficient Federated Edge Learning

Federated edge learning (FEEL) provides a promising foundation for edge artificial intelligence (AI) by enabling collaborative model training while preserving data privacy. However, limited and heterogeneous local datasets, as well as resource-constrained deployment, severely degrade both model generalization and resource utilization, leading to a compromised learning performance. Therefore, we propose a parameter-efficient FEEL framework that jointly leverages model pruning and client selection to tackle such challenges. First, we derive an information-theoretic generalization statement that characterizes the discrepancy between training and testing function losses and embed it into the convergence analysis. It reveals that a larger local generalization statement can undermine the global convergence. Then, we formulate a generalization-aware average squared gradient norm bound minimization problem, by jointly optimizing the pruning ratios, client selection, and communication-computation resources under energy and delay constraints. Despite its non-convexity, the resulting mixed-integer problem is efficiently solved via an alternating optimization algorithm. Extensive experiments demonstrate that the proposed design achieves superior learning performance than state-of-the-art baselines, validating the effectiveness of coupling generalization-aware analysis with system-level optimization for efficient FEEL.

cs.LG↗

arXiv2025

Late-decoupled 3D Hierarchical Semantic Segmentation with Semantic Prototype Discrimination based Bi-branch Supervision

3D hierarchical semantic segmentation (3DHS) is crucial for embodied intelligence applications that demand a multi-grained and multi-hierarchy understanding of 3D scenes. Despite the progress, previous 3DHS methods have overlooked following two challenges: I) multi-label learning with a parameter-sharing model can lead to multi-hierarchy conflicts in cross-hierarchy optimization, and II) the class imbalance issue is inevitable across multiple hierarchies of 3D scenes, which makes the model performance become dominated by major classes. To address these issues, we propose a novel framework with a primary 3DHS branch and an auxiliary discrimination branch. Specifically, to alleviate the multi-hierarchy conflicts, we propose a late-decoupled 3DHS framework which employs multiple decoders with the coarse-to-fine hierarchical guidance and consistency. The late-decoupled architecture can mitigate the underfitting and overfitting conflicts among multiple hierarchies and can also constrain the class imbalance problem in each individual hierarchy. Moreover, we introduce a 3DHS-oriented semantic prototype based bi-branch supervision mechanism, which additionally learns class-wise discriminative point cloud features and performs mutual supervision between the auxiliary and 3DHS branches, to enhance the class-imbalance segmentation. Extensive experiments on multiple datasets and backbones demonstrate that our approach achieves state-of-the-art 3DHS performance, and its core components can also be used as a plug-and-play enhancement to improve previous methods.

cs.CV↗

arXiv2025

Self-Supervised Discriminative Feature Learning for Deep Multi-View Clustering

Multi-view clustering is an important research topic due to its capability to utilize complementary information from multiple views. However, there are few methods to consider the negative impact caused by certain views with unclear clustering structures, resulting in poor multi-view clustering performance. To address this drawback, we propose self-supervised discriminative feature learning for deep multi-view clustering (SDMVC). Concretely, deep autoencoders are applied to learn embedded features for each view independently. To leverage the multi-view complementary information, we concatenate all views' embedded features to form the global features, which can overcome the negative impact of some views' unclear clustering structures. In a self-supervised manner, pseudo-labels are obtained to build a unified target distribution to perform multi-view discriminative feature learning. During this process, global discriminative information can be mined to supervise all views to learn more discriminative features, which in turn are used to update the target distribution. Besides, this unified target distribution can make SDMVC learn consistent cluster assignments, which accomplishes the clustering consistency of multiple views while preserving their features' diversity. Experiments on various types of multi-view datasets show that SDMVC outperforms 14 competitors including classic and state-of-the-art methods. The code is available at https://github.com/SubmissionsIn/SDMVC.

cs.LG↗

arXiv2025

MedBench v4: A Robust and Scalable Benchmark for Evaluating Chinese Medical Language Models, Multimodal Models, and Intelligent Agents

Recent advances in medical large language models (LLMs), multimodal models, and agents demand evaluation frameworks that reflect real clinical workflows and safety constraints. We present MedBench v4, a nationwide, cloud-based benchmarking infrastructure comprising over 700,000 expert-curated tasks spanning 24 primary and 91 secondary specialties, with dedicated tracks for LLMs, multimodal models, and agents. Items undergo multi-stage refinement and multi-round review by clinicians from more than 500 institutions, and open-ended responses are scored by an LLM-as-a-judge calibrated to human ratings. We evaluate 15 frontier models. Base LLMs reach a mean overall score of 54.1/100 (best: Claude Sonnet 4.5, 62.5/100), but safety and ethics remain low (18.4/100). Multimodal models perform worse overall (mean 47.5/100; best: GPT-5, 54.9/100), with solid perception yet weaker cross-modal reasoning. Agents built on the same backbones substantially improve end-to-end performance (mean 79.8/100), with Claude Sonnet 4.5-based agents achieving up to 85.3/100 overall and 88.9/100 on safety tasks. MedBench v4 thus reveals persisting gaps in multimodal reasoning and safety for base models, while showing that governance-aware agentic orchestration can markedly enhance benchmarked clinical readiness without sacrificing capability. By aligning tasks with Chinese clinical guidelines and regulatory priorities, the platform offers a practical reference for hospitals, developers, and policymakers auditing medical AI.

cs.CL↗

arXiv2025

Evaluating the Ability of Large Language Models to Identify Adherence to CONSORT Reporting Guidelines in Randomized Controlled Trials: A Methodological Evaluation Study

The Consolidated Standards of Reporting Trials statement is the global benchmark for transparent and high-quality reporting of randomized controlled trials. Manual verification of CONSORT adherence is a laborious, time-intensive process that constitutes a significant bottleneck in peer review and evidence synthesis. This study aimed to systematically evaluate the accuracy and reliability of contemporary LLMs in identifying the adherence of published RCTs to the CONSORT 2010 statement under a zero-shot setting. We constructed a golden standard dataset of 150 published RCTs spanning diverse medical specialties. The primary outcome was the macro-averaged F1-score for the three-class classification task, supplemented by item-wise performance metrics and qualitative error analysis. Overall model performance was modest. The top-performing models, Gemini-2.5-Flash and DeepSeek-R1, achieved nearly identical macro F1 scores of 0.634 and Cohen's Kappa coefficients of 0.280 and 0.282, respectively, indicating only fair agreement with expert consensus. A striking performance disparity was observed across classes: while most models could identify compliant items with high accuracy (F1 score > 0.850), they struggled profoundly with identifying non-compliant and not applicable items, where F1 scores rarely exceeded 0.400. Notably, some high-profile models like GPT-4o underperformed, achieving a macro F1-score of only 0.521. LLMs show potential as preliminary screening assistants for CONSORT checks, capably identifying well-reported items. However, their current inability to reliably detect reporting omissions or methodological flaws makes them unsuitable for replacing human expertise in the critical appraisal of trial quality.

cs.CL↗

arXiv2025

TCM-5CEval: Extended Deep Evaluation Benchmark for LLM's Comprehensive Clinical Research Competence in Traditional Chinese Medicine

Large language models (LLMs) have demonstrated exceptional capabilities in general domains, yet their application in highly specialized and culturally-rich fields like Traditional Chinese Medicine (TCM) requires rigorous and nuanced evaluation. Building upon prior foundational work such as TCM-3CEval, which highlighted systemic knowledge gaps and the importance of cultural-contextual alignment, we introduce TCM-5CEval, a more granular and comprehensive benchmark. TCM-5CEval is designed to assess LLMs across five critical dimensions: (1) Core Knowledge (TCM-Exam), (2) Classical Literacy (TCM-LitQA), (3) Clinical Decision-making (TCM-MRCD), (4) Chinese Materia Medica (TCM-CMM), and (5) Clinical Non-pharmacological Therapy (TCM-ClinNPT). We conducted a thorough evaluation of fifteen prominent LLMs, revealing significant performance disparities and identifying top-performing models like deepseek\_r1 and gemini\_2\_5\_pro. Our findings show that while models exhibit proficiency in recalling foundational knowledge, they struggle with the interpretative complexities of classical texts. Critically, permutation-based consistency testing reveals widespread fragilities in model inference. All evaluated models, including the highest-scoring ones, displayed a substantial performance degradation when faced with varied question option ordering, indicating a pervasive sensitivity to positional bias and a lack of robust understanding. TCM-5CEval not only provides a more detailed diagnostic tool for LLM capabilities in TCM but aldso exposes fundamental weaknesses in their reasoning stability. To promote further research and standardized comparison, TCM-5CEval has been uploaded to the Medbench platform, joining its predecessor in the "In-depth Challenge for Comprehensive TCM Abilities" special track.

cs.CL↗

arXiv2025

Can Large Language Models Function as Qualified Pediatricians? A Systematic Evaluation in Real-World Clinical Contexts

With the rapid rise of large language models (LLMs) in medicine, a key question is whether they can function as competent pediatricians in real-world clinical settings. We developed PEDIASBench, a systematic evaluation framework centered on a knowledge-system framework and tailored to realistic clinical environments. PEDIASBench assesses LLMs across three dimensions: application of basic knowledge, dynamic diagnosis and treatment capability, and pediatric medical safety and medical ethics. We evaluated 12 representative models released over the past two years, including GPT-4o, Qwen3-235B-A22B, and DeepSeek-V3, covering 19 pediatric subspecialties and 211 prototypical diseases. State-of-the-art models performed well on foundational knowledge, with Qwen3-235B-A22B achieving over 90% accuracy on licensing-level questions, but performance declined ~15% as task complexity increased, revealing limitations in complex reasoning. Multiple-choice assessments highlighted weaknesses in integrative reasoning and knowledge recall. In dynamic diagnosis and treatment scenarios, DeepSeek-R1 scored highest in case reasoning (mean 0.58), yet most models struggled to adapt to real-time patient changes. On pediatric medical ethics and safety tasks, Qwen2.5-72B performed best (accuracy 92.05%), though humanistic sensitivity remained limited. These findings indicate that pediatric LLMs are constrained by limited dynamic decision-making and underdeveloped humanistic care. Future development should focus on multimodal integration and a clinical feedback-model iteration loop to enhance safety, interpretability, and human-AI collaboration. While current LLMs cannot independently perform pediatric care, they hold promise for decision support, medical education, and patient communication, laying the groundwork for a safe, trustworthy, and collaborative intelligent pediatric healthcare system.

cs.CL↗

arXiv2025

Human-Level and Beyond: Benchmarking Large Language Models Against Clinical Pharmacists in Prescription Review

The rapid advancement of large language models (LLMs) has accelerated their integration into clinical decision support, particularly in prescription review. To enable systematic and fine-grained evaluation, we developed RxBench, a comprehensive benchmark that covers common prescription review categories and consolidates 14 frequent types of prescription errors drawn from authoritative pharmacy references. RxBench consists of 1,150 single-choice, 230 multiple-choice, and 879 short-answer items, all reviewed by experienced clinical pharmacists. We benchmarked 18 state-of-the-art LLMs and identified clear stratification of performance across tasks. Notably, Gemini-2.5-pro-preview-05-06, Grok-4-0709, and DeepSeek-R1-0528 consistently formed the first tier, outperforming other models in both accuracy and robustness. Comparisons with licensed pharmacists indicated that leading LLMs can match or exceed human performance in certain tasks. Furthermore, building on insights from our benchmark evaluation, we performed targeted fine-tuning on a mid-tier model, resulting in a specialized model that rivals leading general-purpose LLMs in performance on short-answer question tasks. The main contribution of RxBench lies in establishing a standardized, error-type-oriented framework that not only reveals the capabilities and limitations of frontier LLMs in prescription review but also provides a foundational resource for building more reliable and specialized clinical tools.

cs.CL↗

arXiv2025

FedALT: Federated Fine-Tuning through Adaptive Local Training with Rest-of-World LoRA

Fine-tuning large language models (LLMs) in federated settings enables privacy-preserving adaptation but suffers from cross-client interference due to model aggregation. Existing federated LoRA fine-tuning methods, primarily based on FedAvg, struggle with data heterogeneity, leading to harmful cross-client interference and suboptimal personalization. In this work, we propose \textbf{FedALT}, a novel personalized federated LoRA fine-tuning algorithm that fundamentally departs from FedAvg. Instead of using an aggregated model to initialize local training, each client continues training its individual LoRA while incorporating shared knowledge through a separate Rest-of-World (RoW) LoRA component. To effectively balance local adaptation and global information, FedALT introduces an adaptive mixer that dynamically learns input-specific weightings between the individual and RoW LoRA components, drawing conceptual foundations from the Mixture-of-Experts (MoE) paradigm. Through extensive experiments on NLP benchmarks, we demonstrate that FedALT significantly outperforms state-of-the-art personalized federated LoRA fine-tuning methods, achieving superior local adaptation without sacrificing computational efficiency.

cs.LG↗

arXiv2025

Detection in Bistatic ISAC with Deterministic Sensing and Gaussian Information Signals

Integrated sensing and communications (ISAC) is a disruptive technology enabling future sixth-generation (6G) networks. This paper investigates target detection in a bistatic ISAC system, in which the base station (BS) transmits superimposed ISAC signals comprising both Gaussian information-bearing and deterministic sensing components to simultaneously provide communication and sensing functionalities. First, we develop a Neyman-Pearson (NP)-based detector that effectively utilizes both the deterministic sensing and random communication signals. Closed-form analysis reveals that both signal components contribute to improving the overall detection performance. Subsequently, we optimize the BS transmit beamforming to maximize the detection probability, subject to a minimum signal-to-interference-plus-noise ratio (SINR) constraint for the communication user (CU) and a total transmit power budget at the BS. The resulting non-convex beamforming optimization problem is addressed via semi-definite relaxation (SDR) and successive convex approximation (SCA) techniques. Simulation results demonstrate the superiority of the proposed NP-based detector, which leverages both types of signals, over benchmark schemes that treat information signals as interference. They also reveal that a higher communication-rate threshold directs more transmit power to Gaussian information-bearing signals, thereby diminishing deterministic-signal power and weakening detection performance.

eess.SP↗

arXiv2025

Channel Knowledge Map Construction: Recent Advances and Open Challenges

Channel knowledge map (CKM) has emerged as a pivotal technology for environment-aware wireless communications and sensing, which provides a priori location-specific channel knowledge to facilitate network optimization. Efficient CKM construction is an important technical problem for its effective implementation. This article provides a comprehensive overview of recent advances in CKM construction. First, we examine classical interpolation-based CKM construction methods, highlighting their limitations in practical deployments. Next, we explore image processing and generative artificial intelligence (AI) techniques, which leverage feature extraction to construct CKMs based on environmental knowledge. Furthermore, we present emerging wireless radiance field (WRF) frameworks that exploit neural radiance fields or Gaussian splatting to construct high-fidelity CKMs from sparse measurement data. Finally, we outline various future research directions in real-time and cross-domain CKM construction, as well as cost-efficient deployment of CKMs.

eess.SP↗

arXiv2025

Strong approximation for the intersection of two quadrics

We study strong approximation for the intersection of two affine quadrics. As its application, we prove the fibration method for weak approximation over number fields of rank four with nonsplit fibers split by quadratic extensions.

math.AG↗